| RS749294509 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Renal cyst |
| RS749295454 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS749296628 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Cornelia de Lange syndrome 1 |
| RS749297006 |
WNT10A
|
Health Risk |
Pathogenic |
Tooth agenesis, selective |
| RS749297332 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS749298208 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pancreatic cancer, susceptibility to |
| RS749298368 |
GCK
|
Health Risk |
Likely pathogenic |
Monogenic diabetes, Monogenic diabetes |
| RS749299119 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS749299357 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS749301742 |
TRPM1
|
Health Risk |
Pathogenic |
— |
| RS749301835 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonus, intractable |
| RS749302505 |
DNAI1
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Kartagener syndrome |
| RS749303140 |
PKLR
|
Health Risk |
Pathogenic |
— |
| RS749304523 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Alstrom syndrome |
| RS749304751 |
SPATA7
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 3, Leber congenital amaurosis 3 |
| RS749305408 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, Hereditary cancer-predisposing syndrome |
| RS749305586 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Dilated cardiomyopathy 1G |
| RS749305814 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS749306669 |
CLCN7
|
Health Risk |
Pathogenic |
— |
| RS749307006 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS749307327 |
MPDZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749308557 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS749308804 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS749309384 |
EXPH5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 4, localized or generalized intermediate |
| RS749309440 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS749309577 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Li-Fraumeni syndrome, Hereditary cancer-predisposing syndrome |
| RS749309938 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 39, Retinal dystrophy |
| RS74931017 |
DNAH9
|
Health Risk |
Conflicting classifications of pathogenicity |
DNAH9-related disorder, Inborn genetic diseases |
| RS749310275 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 4, Cardiovascular phenotype |
| RS749311817 |
PCNT
|
Health Risk |
Pathogenic |
— |
| RS749312983 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS749313133 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749314857 |
CEP250
|
Health Risk |
Pathogenic/Likely pathogenic |
Cone-rod dystrophy and hearing loss 2, Usher syndrome |
| RS749315029 |
HOGA1
|
Health Risk |
Likely pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS749315126 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Coffin-Siris syndrome 1, Coffin-Siris syndrome 1 |
| RS749315193 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RAI1-related disorder |
| RS749315456 |
CLCN7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749315686 |
MFSD8
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 7, Late-infantile neuronal ceroid lipofuscinosis |
| RS749316923 |
FH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fumarase deficiency |
| RS749317169 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS749317646 |
SCN1A
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS749317721 |
CTNS
|
Health Risk |
Pathogenic |
Ocular cystinosis, Juvenile nephropathic cystinosis |
| RS749318218 |
MED17
|
Health Risk |
Pathogenic |
— |
| RS749319044 |
PDHA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS749319334 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital nephrotic syndrome, Congenital nephrotic syndrome |
| RS749319462 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749319838 |
CHD5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749320057 |
MME
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2T, Spinocerebellar ataxia 43 |
| RS749320093 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, 6 conditions |
| RS749320240 |
SLC6A3
|
Health Risk |
Likely pathogenic |
— |
| RS749321625 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749322788 |
PPP2R1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749322793 |
BBS9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 9 |
| RS749323139 |
G6PC1
|
Health Risk |
Pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS749323787 |
TREX1
|
Health Risk |
Conflicting classifications of pathogenicity |
TREX1-related disorder, Aicardi-Goutieres syndrome 1 |
| RS749325776 |
SLC26A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 4, Autosomal recessive nonsyndromic hearing loss 4 |
| RS749326176 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS749326394 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Alternating hemiplegia of childhood 1 |
| RS749326729 |
DOCK2
|
Health Risk |
Conflicting classifications of pathogenicity |
DOCK2 deficiency, See cases |
| RS749326764 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS749327297 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS749327820 |
CYFIP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 65 |
| RS749328536 |
ERCC1
|
Health Risk |
Likely pathogenic |
— |
| RS749329916 |
RTN4IP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749330035 |
IFT140
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS749330118 |
TTC21B
|
Health Risk |
Likely pathogenic |
Nephronophthisis 12, TTC21B-related disorder |
| RS749330477 |
D2HGDH
|
Health Risk |
Pathogenic |
D-2-hydroxyglutaric aciduria 1, D-2-hydroxyglutaric aciduria 1 |
| RS749331348 |
CEP290
|
Health Risk |
Pathogenic |
Nephronophthisis, Joubert syndrome |
| RS749331637 |
RTEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal recessive 5 |
| RS749331668 |
ANO10
|
Health Risk |
Likely pathogenic |
— |
| RS749332339 |
POMGNT1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS749334082 |
PIGN
|
Health Risk |
Pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 1, Multiple congenital anomalies-hypotonia-seizures syndrome 1 |
| RS749334182 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS749334262 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS749336034 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS749336515 |
SLC12A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 34 |
| RS749337189 |
SKIC3
|
Health Risk |
Pathogenic |
— |
| RS749337566 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Inborn genetic diseases |
| RS749337739 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS749338434 |
BRD4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749338526 |
NAGLU
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-B |
| RS749338996 |
ADGRG1
|
Health Risk |
Pathogenic |
— |
| RS749339594 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS749339741 |
STIL
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 7, primary |
| RS749339938 |
ALMS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Alstrom syndrome |
| RS749339972 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749340193 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Malignant tumor of esophagus |
| RS749340561 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 11, Cardiovascular phenotype |
| RS749341977 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS749342175 |
PEX5
|
Health Risk |
Likely pathogenic |
Rhizomelic chondrodysplasia punctata type 5, Peroxisome biogenesis disorder 2B |
| RS749343808 |
CPAP
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly 6, primary |
| RS749343954 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal spinal muscular atrophy 1, Charcot-Marie-Tooth disease axonal type 2S |
| RS749345054 |
TWNK
|
Health Risk |
Likely pathogenic |
— |
| RS749345540 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS749345577 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Idiopathic generalized epilepsy |
| RS749346618 |
MYOM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS749346955 |
MEIS2
|
Health Risk |
Pathogenic |
Cardiac malformation, cleft lip/palate |
| RS749347602 |
HEXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Sandhoff disease, Inborn genetic diseases |
| RS749348004 |
COL4A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive Alport syndrome, Autosomal dominant Alport syndrome |
| RS749349816 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |