| RS749094914 |
VAC14
|
Health Risk |
Conflicting classifications of pathogenicity |
Striatonigral degeneration, childhood-onset |
| RS749096548 |
VPS13D
|
Health Risk |
Likely pathogenic |
— |
| RS749096874 |
TYR
|
Health Risk |
Likely pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1B |
| RS749098014 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS749098397 |
RPGRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 13, Leber congenital amaurosis 6 |
| RS749099493 |
CAPN3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS749099779 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS749100905 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS749103517 |
MFF
|
Health Risk |
Likely pathogenic |
— |
| RS749103588 |
CTSC
|
Health Risk |
Pathogenic |
Periodontitis, aggressive 1 |
| RS749103801 |
EYS
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 25 |
| RS749104500 |
GPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Inborn genetic diseases |
| RS749104931 |
RTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS749106645 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS749107412 |
BBS12
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS749108651 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Myopathy |
| RS749110441 |
TMPRSS5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749110767 |
FOXRED1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 19 |
| RS749111054 |
PTH1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Metaphyseal chondrodysplasia, Jansen type |
| RS749111647 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS749112240 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS749114363 |
CEP164
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephronophthisis 15, Nephronophthisis 15 |
| RS749114664 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, Inborn genetic diseases |
| RS749115647 |
ZNF699
|
Health Risk |
Conflicting classifications of pathogenicity |
Diamond-Blackfan anemia, DEGCAGS syndrome |
| RS749116256 |
ADAMTS17
|
Health Risk |
Pathogenic/Likely pathogenic |
Weill-Marchesani 4 syndrome, recessive |
| RS749117997 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Intrauterine growth retardation |
| RS749118285 |
IMPDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Leber congenital amaurosis 11 |
| RS749118441 |
LCT
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lactase deficiency, Congenital lactase deficiency |
| RS749120592 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS749121941 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS749122105 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS749123022 |
AURKC
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749123392 |
TK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome, myopathic form |
| RS749124508 |
ALDH1A2
|
Health Risk |
Pathogenic |
Diaphragmatic hernia 4, with cardiovascular defects |
| RS749124581 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS749124658 |
MICU1
|
Health Risk |
Pathogenic/Likely pathogenic |
Proximal myopathy with extrapyramidal signs, Inborn genetic diseases |
| RS749125197 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS749125278 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS749125299 |
SEC63
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic liver disease 2, Polycystic liver disease 2 |
| RS749126116 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS749126200 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS749127574 |
MMAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblB type |
| RS749127600 |
ATP8B1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749129928 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS749130556 |
SHANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749130573 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS749131549 |
KIF14
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome and related disorders, Joubert syndrome and related disorders |
| RS749132753 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS749133312 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS749134354 |
GNPTAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudo-Hurler polydystrophy, Mucolipidosis type II |
| RS749134845 |
PHGDH
|
Health Risk |
Pathogenic/Likely pathogenic |
PHGDH deficiency, Neu-Laxova syndrome 1 |
| RS749136456 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Rare genetic deafness |
| RS749138071 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS749138739 |
REV3L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749138783 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS749139836 |
SI
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749140168 |
NAGLU
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-B |
| RS749141162 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS749141299 |
GATAD2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome, Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome |
| RS749141857 |
LSS
|
Health Risk |
Pathogenic |
Cataract 44, Cataract 44 |
| RS749142395 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS749142500 |
NOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Regional enteritis |
| RS749144109 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS749145120 |
CASQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy due to calsequestrin and SERCA1 protein overload, Myopathy due to calsequestrin and SERCA1 protein overload |
| RS749145939 |
COL3A1
|
Health Risk |
Likely pathogenic |
Ehlers-Danlos syndrome, type 4 |
| RS749146264 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS749146534 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749147803 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Inborn genetic diseases |
| RS749147965 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS749150627 |
MME
|
Health Risk |
Pathogenic |
— |
| RS749151163 |
ACAN
|
Health Risk |
Pathogenic |
— |
| RS749151809 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS749153163 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Breast and/or ovarian cancer |
| RS749154041 |
TLR4
|
Health Risk |
Conflicting classifications of pathogenicity |
Susceptibility to severe COVID-19, Susceptibility to severe COVID-19 |
| RS749154513 |
ACTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1R, Atrial septal defect 5 |
| RS749154605 |
LAMB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pierson syndrome, LAMB2-related infantile-onset nephrotic syndrome |
| RS749154726 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, Charcot-Marie-Tooth disease |
| RS749154761 |
ADCY5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749154860 |
CHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749155089 |
CASK
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, CASK-related |
| RS749155619 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS749156010 |
MFRP
|
Health Risk |
Likely pathogenic |
Isolated microphthalmia 5, Isolated microphthalmia 5 |
| RS749156425 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS749156618 |
ALG12
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG12-congenital disorder of glycosylation, ALG12-congenital disorder of glycosylation |
| RS749156731 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749157868 |
XIAP
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked lymphoproliferative disease due to XIAP deficiency, Inborn genetic diseases |
| RS749159160 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS749159544 |
SDHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Pheochromocytoma/paraganglioma syndrome 3 |
| RS749159573 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, ACADVL-related disorder |
| RS749160366 |
BPTF
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749160734 |
TGM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS749161770 |
TCF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins syndrome, Pitt-Hopkins syndrome |
| RS749162150 |
LAMA2
|
Health Risk |
Likely pathogenic |
LAMA2-related muscular dystrophy, Merosin deficient congenital muscular dystrophy |
| RS749162303 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS749162799 |
BTD
|
Health Risk |
Pathogenic/Likely pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS749162833 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS749163361 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS749163517 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial infantile myoclonic epilepsy, Inborn genetic diseases |
| RS749163856 |
CFAP251
|
Health Risk |
Pathogenic |
Non-syndromic male infertility due to sperm motility disorder, Male infertility with teratozoospermia due to single gene mutation |
| RS749165759 |
HSD17B4
|
Health Risk |
Conflicting classifications of pathogenicity |
Perrault syndrome, Bifunctional peroxisomal enzyme deficiency |