| RS748917147 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, 11 conditions |
| RS748917509 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Elliptocytosis 2, Hereditary spherocytosis type 3 |
| RS748919077 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748919606 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, Inborn genetic diseases |
| RS748919727 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS748919988 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, POLG-related disorder |
| RS748920885 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS748922513 |
VPS13A
|
Health Risk |
Pathogenic |
Chorea-acanthocytosis, Inborn genetic diseases |
| RS748922639 |
CDC14A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748922857 |
ST3GAL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS748922882 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS748924063 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS748924248 |
TAT
|
Health Risk |
Likely pathogenic |
Tyrosinemia type II, Tyrosinemia type II |
| RS748924643 |
COQ4
|
Health Risk |
Pathogenic/Likely pathogenic |
Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome, COQ4-related disorder |
| RS748925635 |
ALDH18A1
|
Health Risk |
Pathogenic/Likely pathogenic |
ALDH18A1-related de Barsy syndrome, de Barsy syndrome |
| RS748926071 |
DLL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748926167 |
PRF1
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Aplastic anemia |
| RS748926400 |
TYRP1
|
Health Risk |
Likely pathogenic |
— |
| RS748926444 |
SETD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748926718 |
F11
|
Health Risk |
Pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS748926816 |
EGLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrocytosis, familial |
| RS748926976 |
UBE4A
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with hypotonia and gross motor and speech delay, Neurodevelopmental disorder with hypotonia and gross motor and speech delay |
| RS748927280 |
CRB1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 12, Leber congenital amaurosis 8 |
| RS748927298 |
ORC6
|
Health Risk |
Likely pathogenic |
— |
| RS748927848 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS748928044 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS748928605 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748928863 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, Inborn genetic diseases |
| RS748929117 |
DNAI1
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748930248 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS748930384 |
SLX4
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group P |
| RS748930609 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS748930854 |
SKIC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748931188 |
G6PC3
|
Health Risk |
Pathogenic |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
| RS748933560 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748933873 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS748934203 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS748935500 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748935741 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS748936007 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
CREBBP-related disorder, CREBBP-related disorder |
| RS748936034 |
SGCA
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy |
| RS748936457 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Periventricular nodular heterotopia 7, Colon adenocarcinoma |
| RS748936673 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS748936767 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS748937055 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS748937483 |
TMEM67
|
Health Risk |
Pathogenic |
Meckel syndrome, type 3 |
| RS748937501 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS748937918 |
EIF2B3
|
Health Risk |
Likely pathogenic |
— |
| RS748938385 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS748939090 |
HPS1
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome |
| RS748940147 |
COL7A1
|
Health Risk |
Pathogenic |
COL7A1-related disorder, Recessive dystrophic epidermolysis bullosa |
| RS748940418 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS748941040 |
YARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Myopathy, lactic acidosis |
| RS748941459 |
VPS13A
|
Health Risk |
Pathogenic |
— |
| RS748942718 |
PRLR
|
Health Risk |
Likely pathogenic |
Premature ovarian failure, Premature ovarian failure |
| RS748943724 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS748944452 |
NRXN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins-like syndrome 2, Pitt-Hopkins-like syndrome 2 |
| RS748944640 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS748946310 |
ASXL1
|
Health Risk |
Likely pathogenic |
Bohring-Opitz syndrome, Bohring-Opitz syndrome |
| RS748946433 |
DOK7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 10, Fetal akinesia deformation sequence 1 |
| RS748946434 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss, MYH9-related disorder |
| RS748946491 |
PDE6A
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 43 |
| RS748947620 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Porokeratosis 3, disseminated superficial actinic type |
| RS748947682 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS748947919 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS748949261 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital ichthyosis of skin, Congenital ichthyosis of skin |
| RS748949478 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS748949603 |
GNE
|
Health Risk |
Pathogenic |
GNE myopathy, Sialuria |
| RS748949915 |
BICRA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748950533 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS748950751 |
DNAH11
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748950922 |
NPHP4
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS748950933 |
SLC13A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 25 |
| RS748951253 |
TCTN2
|
Health Risk |
Pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS748951603 |
KIZ
|
Health Risk |
Likely pathogenic |
Papillary renal cell carcinoma type 1, Papillary renal cell carcinoma type 1 |
| RS748951777 |
SPTBN1
|
Health Risk |
Likely pathogenic |
Developmental delay, impaired speech |
| RS748952554 |
PTPN11
|
Health Risk |
Likely pathogenic |
RASopathy, RASopathy |
| RS748952768 |
LIFR
|
Health Risk |
Conflicting classifications of pathogenicity |
Stüve-Wiedemann syndrome 1, Stüve-Wiedemann syndrome 1 |
| RS748953233 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency, Rubinstein-Taybi syndrome due to EP300 haploinsufficiency |
| RS748954661 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS748955039 |
SUZ12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748956593 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS748956654 |
PEX5
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 2B, Peroxisome biogenesis disorder 2B |
| RS748958265 |
FANCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS748959693 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS748961218 |
USH2A
|
Health Risk |
Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS748961276 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Ehlers-Danlos syndrome |
| RS748961800 |
FANCI
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group I |
| RS748962730 |
BRIP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group J, Familial cancer of breast |
| RS748962880 |
ALG8
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG8 congenital disorder of glycosylation, ALG8-related disorder |
| RS748963082 |
KIF21A
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital fibrosis of extraocular muscles type 1, Inborn genetic diseases |
| RS748964205 |
GCK
|
Health Risk |
Likely pathogenic |
— |
| RS748964279 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS748964975 |
LARGE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy type B6, LARGE1-related disorder |
| RS748965227 |
STXBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS748965398 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS748965468 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial focal epilepsy with variable foci, DEPDC5-related disorder |
| RS748966916 |
COL6A3
|
Health Risk |
Likely pathogenic |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS748967139 |
CLCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Thyroid cancer, nonmedullary |
| RS748967395 |
CYP11B2
|
Health Risk |
Pathogenic |
CYP11B2-related disorder, CYP11B2-related disorder |