BICRA Chromosome 19
BRD4 interacting chromatin remodeling complex associated protein
Upload your DNA to see your personal genotypes for variants in BICRA.
What This Gene Does
Enables transcription regulator activator activity. Involved in positive regulation of DNA-templated transcription. Located in nucleus. Part of SWI/SNF complex. Implicated in Coffin-Siris syndrome 12. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
GBAF complex subunits
Locus Type
gene with protein product
Location
19q13.33
Ensembl
ENSG00000063169
Associated Conditions (3)
BICRA-related disorder
Coffin-Siris syndrome 12
Intellectual disability
Key Variants
RS1037664603
Conflicting classifications of pathogenicity
Health Risk
RS199973579
Conflicting classifications of pathogenicity
BICRA-related disorder, BICRA-related disorder
Health Risk
RS200735162
Conflicting classifications of pathogenicity
Health Risk
RS200856502
Conflicting classifications of pathogenicity
Health Risk
RS370979982
Conflicting classifications of pathogenicity
Health Risk
RS375127933
Conflicting classifications of pathogenicity
Health Risk
RS376735528
Conflicting classifications of pathogenicity
Health Risk
RS377108443
Conflicting classifications of pathogenicity
Health Risk
RS545666349
Conflicting classifications of pathogenicity
BICRA-related disorder, BICRA-related disorder
Health Risk
RS550911676
Conflicting classifications of pathogenicity
Health Risk
RS566879134
Conflicting classifications of pathogenicity
Health Risk
RS748949915
Conflicting classifications of pathogenicity
Health Risk
All Variants (37)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1037664603 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS199973579 | Health Risk | Conflicting classifications of pathogenicity | BICRA-related disorder, BICRA-related disorder |
| RS200735162 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200856502 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS370979982 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS375127933 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS376735528 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS377108443 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS545666349 | Health Risk | Conflicting classifications of pathogenicity | BICRA-related disorder, BICRA-related disorder |
| RS550911676 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS566879134 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS748949915 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS756990560 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1210103414 | Health Risk | Likely pathogenic | — |
| RS1375723922 | Health Risk | Likely pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS1424525709 | Health Risk | Likely pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2123584685 | Health Risk | Likely pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514110530 | Health Risk | Likely pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514111692 | Health Risk | Likely pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514126893 | Health Risk | Likely pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514130905 | Health Risk | Likely pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514138366 | Health Risk | Likely pathogenic | BICRA-related disorder, BICRA-related disorder |
| RS755506199 | Health Risk | Likely pathogenic | — |
| RS1229548274 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS1490477251 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS1973345860 | Health Risk | Pathogenic | Intellectual disability, Coffin-Siris syndrome 12, Intellectual disability |
| RS1973387849 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2123584339 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2123585052 | Health Risk | Pathogenic | — |
| RS2123588988 | Health Risk | Pathogenic | — |
| RS2123606076 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514108449 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514109185 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514109782 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514111647 | Health Risk | Pathogenic | Coffin-Siris syndrome 12, Coffin-Siris syndrome 12 |
| RS2514111941 | Health Risk | Pathogenic | — |
| RS2514137674 | Health Risk | Pathogenic | — |