| RS748968538 |
SLC35A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autism spectrum disorder - epilepsy - arthrogryposis syndrome, Autism spectrum disorder - epilepsy - arthrogryposis syndrome |
| RS748968589 |
ATP6V0A4
|
Health Risk |
Pathogenic |
— |
| RS748969699 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS748969707 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS748970719 |
SLC34A3
|
Health Risk |
Conflicting classifications of pathogenicity |
SLC34A3-related disorder, SLC34A3-related disorder |
| RS748970759 |
TNNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Dilated cardiomyopathy 1D |
| RS748972176 |
HESX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Septo-optic dysplasia sequence, GROWTH HORMONE DEFICIENCY WITH PITUITARY ANOMALIES |
| RS748972179 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS748972748 |
TULP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 15, Retinitis pigmentosa 14 |
| RS748974113 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS748974194 |
DPYD
|
Health Risk |
Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS748974541 |
UNG
|
Health Risk |
Likely pathogenic |
Hyper-IgM syndrome type 5, Colorectal cancer |
| RS748974608 |
PROM1
|
Health Risk |
Pathogenic |
— |
| RS748977074 |
ATP6AP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability Hedera type, Inborn genetic diseases |
| RS748977292 |
EYS
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 25, Retinitis pigmentosa 25 |
| RS748977698 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS748978134 |
SPINK5
|
Health Risk |
Likely pathogenic |
Netherton syndrome, Ichthyosis linearis circumflexa |
| RS748978993 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS748979061 |
GRM6
|
Health Risk |
Pathogenic |
— |
| RS748980218 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS748980441 |
TPP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Evans syndrome, immunodeficiency |
| RS748980961 |
PMM2
|
Health Risk |
Conflicting classifications of pathogenicity |
PMM2-congenital disorder of glycosylation, PMM2-related disorder |
| RS748981591 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS748981899 |
GNAT2
|
Health Risk |
Pathogenic |
Achromatopsia 4, Achromatopsia 4 |
| RS748982784 |
ALG11
|
Health Risk |
Pathogenic |
ALG11-congenital disorder of glycosylation, ALG11-congenital disorder of glycosylation |
| RS748983205 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748983257 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Encephalopathy due to GLUT1 deficiency, Dystonia 9 |
| RS748983904 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 39, Retinal dystrophy |
| RS748984540 |
STUB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Spinocerebellar ataxia 48, Spinocerebellar ataxia 48 |
| RS748984657 |
RP1L1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 88, Retinitis pigmentosa 88 |
| RS748985164 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS748985200 |
FYCO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cataract 18, Cataract 18 |
| RS748986619 |
DEPDC5
|
Health Risk |
Pathogenic |
Familial focal epilepsy with variable foci, Familial focal epilepsy with variable foci |
| RS748986705 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS748987495 |
PC
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate carboxylase deficiency, Inborn genetic diseases |
| RS748988275 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS748989557 |
FLVCR1
|
Health Risk |
Likely pathogenic |
Stargardt disease, Stargardt disease |
| RS748990736 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS748991295 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS748991956 |
LGI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant epilepsy with auditory features, Inborn genetic diseases |
| RS748993057 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748993388 |
CNGB3
|
Health Risk |
Pathogenic |
Achromatopsia 3, Achromatopsia 3 |
| RS748993808 |
STAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 47 |
| RS748994888 |
TRMT10A
|
Health Risk |
Pathogenic/Likely pathogenic |
See cases, Microcephaly |
| RS748997539 |
NBAS
|
Health Risk |
Pathogenic |
— |
| RS748997622 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS748997644 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures, Inborn genetic diseases |
| RS748998633 |
MYLK3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748999002 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS748999076 |
VPS13A
|
Health Risk |
Pathogenic/Likely pathogenic |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS748999850 |
PRG4
|
Health Risk |
Pathogenic |
Camptodactyly-arthropathy-coxa vara-pericarditis syndrome, Camptodactyly-arthropathy-coxa vara-pericarditis syndrome |
| RS749000334 |
TTN
|
Health Risk |
Likely pathogenic |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1G |
| RS749000689 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS749000879 |
DPM3
|
Health Risk |
Pathogenic |
DPM3-congenital disorder of glycosylation, DPM3-congenital disorder of glycosylation |
| RS749001381 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS749001511 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS749001958 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749002214 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS749003041 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749003514 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marshall syndrome, Stickler syndrome type 2 |
| RS749004212 |
PKD2
|
Health Risk |
Pathogenic |
Autosomal dominant polycystic kidney disease, Polycystic kidney disease |
| RS749004984 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS749005373 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS749005420 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS74900634 |
POR
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital adrenal hyperplasia, Congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency |
| RS749007253 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS749007293 |
MYH7
|
Health Risk |
Pathogenic |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS749008572 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS749008952 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS749009273 |
TJP2
|
Health Risk |
Pathogenic |
Cholestasis, progressive familial intrahepatic |
| RS749009747 |
COL18A1
|
Health Risk |
Pathogenic |
Knobloch syndrome, Knobloch syndrome 1 |
| RS749011772 |
KIZ
|
Health Risk |
Pathogenic |
— |
| RS749012012 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS749012133 |
CNGA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 49, Retinal dystrophy |
| RS749012180 |
GPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749012588 |
NPC1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type C1 |
| RS749012756 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS749012928 |
LRSAM1
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2P, Inborn genetic diseases |
| RS749012938 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS749013429 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS749013749 |
GUCA1A
|
Health Risk |
Pathogenic |
Cone dystrophy 3, Retinal dystrophy |
| RS749013790 |
SI
|
Health Risk |
Likely pathogenic |
— |
| RS749013931 |
ACTA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS749014065 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS749014188 |
GBA1
|
Health Risk |
Likely pathogenic |
Gaucher disease, Gaucher disease type I |
| RS749015246 |
ARSB
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS749017489 |
BBS4
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS749017984 |
TNFRSF13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS749018114 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Myopathy |
| RS749018115 |
MYO5B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital microvillous atrophy, Congenital microvillous atrophy |
| RS749018170 |
POMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS749018985 |
TCTN3
|
Health Risk |
Pathogenic |
Orofacial-digital syndrome IV, Joubert syndrome 18 |
| RS749019037 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Periventricular nodular heterotopia 7, Periventricular nodular heterotopia 7 |
| RS749019340 |
FBXO7
|
Health Risk |
Pathogenic/Likely pathogenic |
Parkinsonian-pyramidal syndrome, Parkinsonian-pyramidal syndrome |
| RS749019982 |
SEPTIN9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749020375 |
GLB1
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-IV-B |
| RS749020872 |
SLC4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
11 conditions, 11 conditions |
| RS749022707 |
TRPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Trichorhinophalangeal syndrome, type III |
| RS749024135 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS749025131 |
OBSCN
|
Health Risk |
Pathogenic |
Hearing loss, autosomal recessive 120 |