| RS748759848 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome due to tenascin-X deficiency, Cardiovascular phenotype |
| RS748759945 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748761213 |
PSAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Sphingolipid activator protein 1 deficiency, Combined PSAP deficiency |
| RS748762287 |
HSPB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2F, Charcot-Marie-Tooth disease axonal type 2F |
| RS748762580 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Lynch syndrome 1 |
| RS748763015 |
NFKB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS748763466 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS748763552 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS748763892 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS74876396 |
TREX1
|
Health Risk |
Likely pathogenic |
Aicardi-Goutieres syndrome 1, Aicardi-Goutieres syndrome 1 |
| RS748765057 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS748766312 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748766458 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease due to ABCA3 deficiency, Hereditary pulmonary alveolar proteinosis |
| RS74876702 |
RNASEH2B
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 2, Aicardi-Goutieres syndrome 2 |
| RS748767112 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Haddad syndrome, Hereditary cancer-predisposing syndrome |
| RS748767202 |
CEP152
|
Health Risk |
Likely pathogenic |
Seckel syndrome 5, Microcephaly 9 |
| RS748767737 |
SCN1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Generalized epilepsy with febrile seizures plus, type 2 |
| RS748768461 |
NLRP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cryopyrin associated periodic syndrome, Chronic infantile neurological |
| RS748768672 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS748769354 |
WHRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 31, Usher syndrome type 2D |
| RS748769566 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Dilated cardiomyopathy 3B |
| RS748772899 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant cerebellar ataxia, Charcot-Marie-Tooth disease axonal type 2O |
| RS748772971 |
PLK4
|
Health Risk |
Pathogenic |
— |
| RS748773142 |
MIA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748774036 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Periventricular nodular heterotopia 7, Periventricular nodular heterotopia 7 |
| RS748774784 |
AP4B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 47, Hereditary spastic paraplegia |
| RS748776990 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS748777325 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
FGFR2-related disorder, FGFR2-related disorder |
| RS748777382 |
TSEN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontoneocerebellar hypoplasia, Pontoneocerebellar hypoplasia |
| RS748777581 |
COL10A1
|
Health Risk |
Likely pathogenic |
— |
| RS748777783 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS748778102 |
ZNF341
|
Health Risk |
Likely pathogenic |
— |
| RS748778907 |
RAD9B
|
Health Risk |
Pathogenic |
Neural tube defect, Neural tube defect |
| RS748779058 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
8 conditions, 8 conditions |
| RS748779390 |
SLC6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy with myoclonic atonic seizures, Epilepsy with myoclonic atonic seizures |
| RS748779475 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Peroxisome biogenesis disorder |
| RS748779965 |
NARS2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 24, Combined oxidative phosphorylation defect type 24 |
| RS748780206 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS748780943 |
GSS
|
Health Risk |
Pathogenic |
Glutathione synthetase deficiency with 5-oxoprolinuria, Glutathione synthetase deficiency with 5-oxoprolinuria |
| RS748781625 |
CTNNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748783182 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS748783975 |
ALDH5A1
|
Health Risk |
Likely pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS748784115 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS748785128 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS748785284 |
AAGAB
|
Health Risk |
Pathogenic |
Palmoplantar keratoderma, punctate type 1A |
| RS748785824 |
BBS1;ZDHHC24
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS748786108 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 3B, Duchenne muscular dystrophy |
| RS748787050 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Shprintzen-Goldberg syndrome |
| RS748787177 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748787734 |
TUBB4A
|
Health Risk |
Likely pathogenic |
Hypomyelinating leukodystrophy 6, Hypomyelinating leukodystrophy 6 |
| RS748787779 |
DIS3L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Perlman syndrome, Perlman syndrome |
| RS748788136 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS748788377 |
ELAC2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 17, Combined oxidative phosphorylation defect type 17 |
| RS74878897 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, POLE-related disorder |
| RS748789700 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS748789925 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 77, Autosomal recessive nonsyndromic hearing loss 77 |
| RS748790230 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Cardiomyopathy |
| RS748790273 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS748791414 |
CFH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Malignant lymphoma |
| RS748791502 |
MGAT2
|
Health Risk |
Likely pathogenic |
— |
| RS748792378 |
PHEX
|
Health Risk |
Pathogenic |
Familial X-linked hypophosphatemic vitamin D refractory rickets, Familial X-linked hypophosphatemic vitamin D refractory rickets |
| RS748793138 |
SMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type A |
| RS748793270 |
WDR81
|
Health Risk |
Conflicting classifications of pathogenicity |
Hydrocephalus, congenital |
| RS748793969 |
DUOX2
|
Health Risk |
Likely pathogenic |
Nongoitrous Euthyroid Hyperthyrotropinemia, Thyroid dyshormonogenesis 6 |
| RS748795143 |
MFAP5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS748797209 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS748798133 |
FKRP
|
Health Risk |
Pathogenic |
Walker-Warburg congenital muscular dystrophy, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS748798324 |
GUCY2D
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 6, Choroidal dystrophy |
| RS748798523 |
TBC1D32
|
Health Risk |
Likely pathogenic |
Joubert syndrome 36, Joubert syndrome 36 |
| RS748798632 |
ENPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Arterial calcification, generalized |
| RS748799148 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS748799656 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS748801701 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS748801711 |
ABCC2
|
Health Risk |
Pathogenic |
— |
| RS748801798 |
IL7R
|
Health Risk |
Pathogenic |
Immunodeficiency 104, Immunodeficiency 104 |
| RS748801869 |
SNTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 12, Long QT syndrome |
| RS748802577 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS748804342 |
AHI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Inborn genetic diseases |
| RS74880446 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 1 |
| RS748805008 |
TCOF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Treacher Collins syndrome 1, Treacher Collins syndrome 1 |
| RS748805290 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Arrhythmogenic right ventricular dysplasia 2 |
| RS748806220 |
EDAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypohidrotic ectodermal dysplasia, Ectodermal dysplasia 10A |
| RS748808582 |
CARD14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Pityriasis rubra pilaris |
| RS748809209 |
RXYLT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a |
| RS748809300 |
MYL11
|
Health Risk |
Pathogenic/Likely pathogenic |
Distal arthrogryposis, Arthrogryposis |
| RS748809560 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS748809573 |
MYOZ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS748809628 |
GFM1
|
Health Risk |
Likely pathogenic |
— |
| RS748809831 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, RYR1-related disorder |
| RS748809942 |
GNPTAB
|
Health Risk |
Pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS748809996 |
PDZRN3
|
Health Risk |
Likely pathogenic |
Childhood-onset schizophrenia, Childhood-onset schizophrenia |
| RS748810004 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS748810619 |
ADA
|
Health Risk |
Likely pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS748810737 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS748811222 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS748811241 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS748811826 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748811873 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS748812251 |
FAM111A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748812609 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |