| RS748583869 |
CNGA3
|
Health Risk |
Pathogenic |
Achromatopsia 2, Achromatopsia 2 |
| RS748584140 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS748584848 |
SLC27A5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748586810 |
METTL8;DCAF17
|
Health Risk |
Conflicting classifications of pathogenicity |
Woodhouse-Sakati syndrome, Nonpapillary renal cell carcinoma |
| RS748587720 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS748587973 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 5, Autosomal recessive spinocerebellar ataxia 14 |
| RS748588125 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Gastrointestinal stromal tumor |
| RS748589398 |
RAD51C
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS748589919 |
SMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type A |
| RS748590408 |
RXYLT1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS748590759 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, CHARGE syndrome |
| RS748591104 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS748592523 |
PDE6C
|
Health Risk |
Likely pathogenic |
— |
| RS748592740 |
ACTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Actin accumulation myopathy, Actin accumulation myopathy |
| RS748594806 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS748595405 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS748595772 |
HAX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Kostmann syndrome, Kostmann syndrome |
| RS748597382 |
KCNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 26 |
| RS748597500 |
DGUOK
|
Health Risk |
Pathogenic |
Mitochondrial DNA depletion syndrome 3 (hepatocerebral type), Portal hypertension |
| RS748597598 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Sotos syndrome |
| RS748598334 |
TTC21B
|
Health Risk |
Likely pathogenic |
Nephronophthisis, Jeune thoracic dystrophy |
| RS748598593 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS748599073 |
CEP120
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 13 with or without polydactyly, Inborn genetic diseases |
| RS748600162 |
SPG7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748600370 |
DNAAF3
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748600834 |
GATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Arginine:glycine amidinotransferase deficiency, Fanconi renotubular syndrome 1 |
| RS748601201 |
BBS10
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 10 |
| RS748601646 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS748601675 |
BBS9
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 9 |
| RS748602445 |
SGCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2E, Autosomal recessive limb-girdle muscular dystrophy type 2E |
| RS748602773 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS748603087 |
AKT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cowden syndrome 6 |
| RS748603743 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS748604051 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS748604898 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS748606221 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome |
| RS748607156 |
PPP2R5D
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748609458 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS748610273 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS748610718 |
TGM5
|
Health Risk |
Pathogenic |
Acral peeling skin syndrome, Acral peeling skin syndrome |
| RS748611349 |
PCDH19
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 9 |
| RS748612396 |
DNAH1
|
Health Risk |
Likely pathogenic |
— |
| RS748613519 |
ATR
|
Health Risk |
Conflicting classifications of pathogenicity |
Seckel syndrome 1, Seckel syndrome 1 |
| RS748613561 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS748614674 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Haddad syndrome, Hereditary cancer-predisposing syndrome |
| RS748615072 |
TBCD
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS748616468 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS748616891 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, Cardiovascular phenotype |
| RS74861744 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Autoinflammatory syndrome |
| RS748617459 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS748617936 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS74861804 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, COL7A1-related disorder |
| RS748618094 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Male infertility |
| RS74861823 |
ZNF407
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748618811 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Werner syndrome |
| RS748619096 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS748619848 |
ACTN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 1, Focal segmental glomerulosclerosis 1 |
| RS748621056 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS748621675 |
ADAMTSL4
|
Health Risk |
Pathogenic |
— |
| RS748622028 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Juvenile polyposis syndrome |
| RS748622672 |
SMAD6
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic valve disease 2, Inborn genetic diseases |
| RS748623569 |
HADH
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of 3-hydroxyacyl-CoA dehydrogenase, Hyperinsulinemic hypoglycemia |
| RS748624161 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Alstrom syndrome |
| RS748624682 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Autoinflammatory syndrome |
| RS748624754 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS748624980 |
CHRNE
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome, Congenital myasthenic syndrome 4A |
| RS748625715 |
LAMB1
|
Health Risk |
Pathogenic |
— |
| RS748628129 |
SLC1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748629190 |
CREB3L3
|
Health Risk |
Pathogenic |
— |
| RS748629721 |
MPDZ
|
Health Risk |
Pathogenic |
— |
| RS748632114 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Oligodontia-cancer predisposition syndrome |
| RS748632850 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS748634340 |
TDRD9
|
Health Risk |
Likely pathogenic |
Male infertility, Male infertility |
| RS748634683 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial focal epilepsy with variable foci, Inborn genetic diseases |
| RS748634900 |
ATM
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS748635133 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS748635750 |
CELSR1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748635985 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Familial cancer of breast |
| RS748636033 |
MINPP1
|
Health Risk |
Likely pathogenic |
Pontocerebellar hypoplasia, type 16 |
| RS748636047 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS748636051 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome and Noonan-related syndrome, Cardiovascular phenotype |
| RS748636216 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS748637278 |
UBE3B
|
Health Risk |
Pathogenic |
Oculocerebrofacial syndrome, Kaufman type |
| RS748637480 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS748639083 |
PREPL
|
Health Risk |
Pathogenic |
Myasthenic syndrome, congenital |
| RS748639289 |
AP4M1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 50, Hereditary spastic paraplegia 50 |
| RS748639603 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS748639813 |
HRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Costello syndrome, 6 conditions |
| RS748640706 |
ETFDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS748641028 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Brain abnormalities, neurodegeneration |
| RS748641277 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS748641688 |
SERAC1
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria with deafness, encephalopathy |
| RS748642981 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS748643212 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, seizures |
| RS748643448 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS748643562 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS748643694 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS748643730 |
OFD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rare genetic intellectual disability, Joubert syndrome |
| RS748644115 |
MITF
|
Health Risk |
Conflicting classifications of pathogenicity |
Waardenburg syndrome type 2A, Tietz syndrome |
| RS748644391 |
ATP7B
|
Health Risk |
Likely pathogenic |
Wilson disease, Wilson disease |