| RS748394046 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS748394238 |
CERKL
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 26, Retinal dystrophy |
| RS748394297 |
MTO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency, Inborn genetic diseases |
| RS748394417 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, FG syndrome |
| RS748394731 |
SLC25A20
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine acylcarnitine translocase deficiency, SLC25A20-related disorder |
| RS748396067 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS748396149 |
PLEKHG2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748396645 |
PCARE
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 54 |
| RS748397131 |
RTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 12, Spastic paraplegia |
| RS748397580 |
MTHFR
|
Health Risk |
Likely pathogenic |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, Neural tube defects |
| RS748398268 |
HOXD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Skeletal dysplasia, Skeletal dysplasia |
| RS748398314 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Inborn genetic diseases |
| RS748398869 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS748398941 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS748399477 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Dilated cardiomyopathy 1C |
| RS748399766 |
SLC24A1
|
Health Risk |
Pathogenic |
Malignant tumor of urinary bladder, Malignant tumor of urinary bladder |
| RS748399924 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748400155 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Continuous spike and waves during slow sleep |
| RS748400535 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS748400605 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS748401794 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant cerebellar ataxia, Autosomal dominant cerebellar ataxia |
| RS748402153 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia 10 |
| RS748402163 |
HARS2
|
Health Risk |
Likely pathogenic |
Perrault syndrome 2, Perrault syndrome 2 |
| RS748402420 |
SLC7A9
|
Health Risk |
Likely pathogenic |
Cystinuria, Cystinuria |
| RS748402485 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS748402637 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital ichthyosis of skin, Congenital ichthyosis of skin |
| RS748404277 |
VPS13B
|
Health Risk |
Pathogenic |
Cohen syndrome, Abnormality of the eye |
| RS748404777 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS748404878 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, FBXL4-related disorder |
| RS748407052 |
CUBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Imerslund-Grasbeck syndrome, Imerslund-Grasbeck syndrome |
| RS748407996 |
PRPF8
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS748408098 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS748408459 |
SRD5A3
|
Health Risk |
Conflicting classifications of pathogenicity |
SRD5A3-congenital disorder of glycosylation, Inborn genetic diseases |
| RS748410422 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS748411156 |
SMPD1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type A |
| RS748412274 |
CDHR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 15, Cone-rod dystrophy 15 |
| RS748412471 |
TDRD7
|
Health Risk |
Likely pathogenic |
Cataract 36, Cataract 36 |
| RS748412838 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Myopathy |
| RS748413058 |
DMXL2
|
Health Risk |
Likely pathogenic |
— |
| RS748413124 |
ABCA12
|
Health Risk |
Pathogenic |
Autosomal recessive congenital ichthyosis 4A, Autosomal recessive congenital ichthyosis 4B |
| RS748413646 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease type 4 |
| RS748413985 |
TBC1D8B
|
Health Risk |
Pathogenic |
Nephrotic syndrome, type 20 |
| RS748414191 |
LRBA
|
Health Risk |
Pathogenic |
Combined immunodeficiency due to LRBA deficiency, Combined immunodeficiency due to LRBA deficiency |
| RS748415049 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS748416710 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Inborn genetic diseases |
| RS748416758 |
FLNC
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Cardiomyopathy |
| RS748416799 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome with C3 anomaly, Age related macular degeneration 9 |
| RS748417604 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS748417793 |
ZFX
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, X-linked |
| RS748418658 |
CD27
|
Health Risk |
Pathogenic |
Lymphoproliferative syndrome 2, Lymphoproliferative syndrome 2 |
| RS748419325 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Congenital contractural arachnodactyly |
| RS748419907 |
PRRT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic kinesigenic dyskinesia, Episodic kinesigenic dyskinesia |
| RS748420513 |
OCRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Lowe syndrome, Nephrolithiasis/nephrocalcinosis |
| RS748422794 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748423430 |
MLH1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS748423645 |
ERCC6
|
Health Risk |
Likely pathogenic |
— |
| RS748424210 |
ACVR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myositis ossificans, Progressive myositis ossificans |
| RS748424414 |
DVL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748424712 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS748424949 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS748425041 |
ACAT1
|
Health Risk |
Likely pathogenic |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS748427000 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS748427458 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS748428531 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 4 |
| RS748428663 |
SLC4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 4, Hemolytic anemia |
| RS748430513 |
NEK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 9, Nephronophthisis 9 |
| RS748430621 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS748431296 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS748431584 |
CD36
|
Health Risk |
Pathogenic |
CD36-related disorder, Platelet-type bleeding disorder 10 |
| RS748431827 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS748432349 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS748432685 |
GHRHR
|
Health Risk |
Pathogenic |
— |
| RS748433510 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Cardiovascular phenotype |
| RS748436283 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH3-related disorder, MYH3-related disorder |
| RS748436953 |
WASHC4
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal recessive 43 |
| RS748437548 |
PCK1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748438266 |
C8A
|
Health Risk |
Pathogenic |
— |
| RS748438350 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome |
| RS748439275 |
DDC
|
Health Risk |
Likely pathogenic |
Deficiency of aromatic-L-amino-acid decarboxylase, Deficiency of aromatic-L-amino-acid decarboxylase |
| RS748440351 |
COL11A2
|
Health Risk |
Pathogenic |
Heart, malformation of |
| RS748440695 |
DNAAF4
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS748440817 |
SDHC
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS748441485 |
SMARCB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS748442113 |
OCLN
|
Health Risk |
Pathogenic/Likely pathogenic |
Pseudo-TORCH syndrome 1, Pseudo-TORCH syndrome 1 |
| RS748442759 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748445058 |
PNPT1
|
Health Risk |
Likely pathogenic |
Spinocerebellar ataxia type 25, Spinocerebellar ataxia type 25 |
| RS748445140 |
KCNJ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial fibrillation, familial |
| RS748447513 |
CYP11B1
|
Health Risk |
Likely pathogenic |
— |
| RS748448687 |
FCHO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748449813 |
ELP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Medulloblastoma, Familial dysautonomia |
| RS748450705 |
KATNIP
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS748450834 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS748450888 |
TUBGCP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748451307 |
CREBBP
|
Health Risk |
Pathogenic |
Rubinstein-Taybi syndrome due to CREBBP mutations, Rubinstein-Taybi syndrome due to CREBBP mutations |
| RS748451478 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS748453057 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS748453083 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked intellectual disability with marfanoid habitus, Cholestasis-pigmentary retinopathy-cleft palate syndrome |
| RS748453607 |
NBN
|
Health Risk |
Pathogenic |
Microcephaly, normal intelligence and immunodeficiency |
| RS748453696 |
NEUROG1
|
Health Risk |
Pathogenic |
Cranial dysinnervation disorder, congenital |
| RS748453841 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |