| RS748321474 |
GLI1
|
Health Risk |
Pathogenic |
Polydactyly, postaxial |
| RS748322684 |
C14orf39
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 52, Premature ovarian failure 18 |
| RS748323629 |
UBR4
|
Health Risk |
Likely pathogenic |
Short stature, Short stature |
| RS748323823 |
DES
|
Health Risk |
Likely pathogenic |
Desmin-related myofibrillar myopathy, Cardiovascular phenotype |
| RS748324481 |
FMO3
|
Health Risk |
Pathogenic/Likely pathogenic |
Trimethylaminuria, Trimethylaminuria |
| RS748325646 |
ZIC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Heterotaxy, visceral |
| RS748325824 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, Cholestanol storage disease |
| RS748326281 |
SYNE4
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 76, Ovarian serous cystadenocarcinoma |
| RS748326514 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS748326759 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS748327110 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS748327743 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS748329498 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Clear cell carcinoma of kidney |
| RS74832989 |
HIBCH
|
Health Risk |
Pathogenic/Likely pathogenic |
3-hydroxyisobutyryl-CoA hydrolase deficiency, 3-hydroxyisobutyryl-CoA hydrolase deficiency |
| RS748330320 |
CIITA
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class II deficiency, CIITA-related disorder |
| RS748330438 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS748331529 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS748333147 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS748333323 |
HOXB13
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Prostate cancer |
| RS748333558 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Global developmental delay, Intellectual disability |
| RS748334413 |
GYS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease due to muscle and heart glycogen synthase deficiency, Glycogen storage disease due to muscle and heart glycogen synthase deficiency |
| RS748335175 |
RARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontocerebellar hypoplasia type 6, Pontocerebellar hypoplasia type 6 |
| RS748335411 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder, Neurodevelopmental disorder |
| RS748335429 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS748335793 |
TRAF3IP1
|
Health Risk |
Pathogenic |
— |
| RS748335883 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748335936 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS748336996 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Dystonia 28, childhood-onset |
| RS748337315 |
FANCE
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS748337491 |
SON
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748337823 |
PAH
|
Health Risk |
Pathogenic |
Phenylketonuria, Phenylketonuria |
| RS748337915 |
SUMF1
|
Health Risk |
Pathogenic |
Multiple sulfatase deficiency, Multiple sulfatase deficiency |
| RS748340868 |
ADAMTS2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS748342368 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group C |
| RS748342378 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS748343919 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 5, Cardiomyopathy |
| RS748343941 |
HFM1
|
Health Risk |
Pathogenic |
Spermatogenic failure 4, Spermatogenic failure 4 |
| RS748345018 |
TPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 2, Inborn genetic diseases |
| RS748345425 |
DRC1
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748345448 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS748345527 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
GM1 gangliosidosis, Mucopolysaccharidosis |
| RS748345928 |
ELANE
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutropenia, severe congenital |
| RS748348196 |
ACE
|
Health Risk |
Pathogenic |
— |
| RS748349854 |
IARS1
|
Health Risk |
Likely pathogenic |
— |
| RS748350251 |
RFT1
|
Health Risk |
Conflicting classifications of pathogenicity |
RFT1-congenital disorder of glycosylation, RFT1-congenital disorder of glycosylation |
| RS748350342 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS748351421 |
BEST1
|
Health Risk |
Pathogenic |
Vitelliform macular dystrophy 2, Vitelliform macular dystrophy 2 |
| RS748352319 |
RB1
|
Health Risk |
Pathogenic |
Retinoblastoma, Retinoblastoma |
| RS748353137 |
NGLY1
|
Health Risk |
Pathogenic |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation |
| RS748353498 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Cataract 41 |
| RS748354081 |
CNGB3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748354087 |
ZEB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mowat-Wilson syndrome, Inborn genetic diseases |
| RS748354630 |
IL21R
|
Health Risk |
Conflicting classifications of pathogenicity |
Cryptosporidiosis-chronic cholangitis-liver disease syndrome, Inborn genetic diseases |
| RS748354696 |
GALE
|
Health Risk |
Conflicting classifications of pathogenicity |
UDPglucose-4-epimerase deficiency, UDPglucose-4-epimerase deficiency |
| RS748356668 |
LAMA2
|
Health Risk |
Pathogenic |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS748357067 |
ABCA4
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Retinal dystrophy |
| RS748358450 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy, Nemaline myopathy 2 |
| RS748358807 |
MMUT
|
Health Risk |
Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency |
| RS748362676 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS748362724 |
SLC4A11
|
Health Risk |
Conflicting classifications of pathogenicity |
Corneal dystrophy-perceptive deafness syndrome, Corneal dystrophy-perceptive deafness syndrome |
| RS748363079 |
ARID1B
|
Health Risk |
Pathogenic |
Coffin-Siris syndrome 1, Coffin-Siris syndrome 1 |
| RS748363083 |
G6PC1
|
Health Risk |
Pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS748363549 |
CLCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748363597 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS748363919 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS748364235 |
NACC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748365248 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS748369241 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS748369265 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1G |
| RS748369269 |
SCN5A
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS748369458 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 39, Retinitis pigmentosa 39 |
| RS748370008 |
LCA5
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 5, Retinal dystrophy |
| RS748371566 |
SIK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 30 |
| RS748371797 |
POLE
|
Health Risk |
Pathogenic |
— |
| RS748373029 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS748373099 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS748373933 |
CHMP1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontocerebellar hypoplasia type 8, Inborn genetic diseases |
| RS748374119 |
FANCI
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS748374528 |
CTH
|
Health Risk |
Pathogenic |
Cystathioninuria, Cystathioninuria |
| RS748375168 |
DNAH8
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748375797 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS748379243 |
ERCC8
|
Health Risk |
Pathogenic |
Cockayne syndrome type 1, Cockayne syndrome type 1 |
| RS748379353 |
LAMC2
|
Health Risk |
Likely pathogenic |
— |
| RS748379474 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, Cardiovascular phenotype |
| RS748380897 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS748382770 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS748382994 |
ACSF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS748383126 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748383863 |
USH2A
|
Health Risk |
Pathogenic |
— |
| RS748384232 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness, congenital heart defects |
| RS748384890 |
SPTLC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 1, Inborn genetic diseases |
| RS748385144 |
LIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to DCLRE1C deficiency, DNA ligase IV deficiency |
| RS748385953 |
DDHD1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 28, Hereditary spastic paraplegia 28 |
| RS748387885 |
HGSNAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS748389002 |
GNPTAB
|
Health Risk |
Likely pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS748390169 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Brugada syndrome 8 |
| RS748391176 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748393033 |
CSRP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1M, Hypertrophic cardiomyopathy 12 |
| RS748393505 |
SETBP1
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Intellectual disability |
| RS748393514 |
PCCB
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |