| RS748186190 |
OCRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Lowe syndrome, Dent disease type 2 |
| RS748186908 |
BLM
|
Health Risk |
Pathogenic/Likely pathogenic |
Bloom syndrome, Bloom syndrome |
| RS748186935 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS748187062 |
HADHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial trifunctional protein deficiency, Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency |
| RS748187466 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748188421 |
IFI44
|
Health Risk |
risk factor |
Multisystem inflammatory syndrome in children, Multisystem inflammatory syndrome in children |
| RS748190164 |
HEXA
|
Health Risk |
Pathogenic/Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS748190695 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 10, Noonan syndrome 2 |
| RS748192983 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS748194118 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS748194265 |
DUOX2
|
Health Risk |
Pathogenic/Likely pathogenic |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS748194372 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS748194962 |
COL27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748196998 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS748198629 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS748200691 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 39, Retinal dystrophy |
| RS748200741 |
MSN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748200917 |
ADAMTS18
|
Health Risk |
Conflicting classifications of pathogenicity |
ADAMTS18-related disorder, ADAMTS18-related disorder |
| RS748201094 |
EVC
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS748201122 |
MCCC1
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 1 deficiency, 3-methylcrotonyl-CoA carboxylase 1 deficiency |
| RS748202003 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS748202049 |
MYZAP
|
Health Risk |
Pathogenic |
Cardiomyopathy, dilated |
| RS748203170 |
NPHS2
|
Health Risk |
Likely pathogenic |
Nephrotic syndrome, type 2 |
| RS748203708 |
ASL
|
Health Risk |
Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS748203812 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS748204076 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS748204331 |
SAG
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS748204442 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS748204512 |
ATP2C1
|
Health Risk |
Pathogenic |
Familial benign pemphigus, Familial benign pemphigus |
| RS748205778 |
WFS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Wolfram-like syndrome, Wolfram syndrome 1 |
| RS748206266 |
LCT
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital lactase deficiency, Congenital lactase deficiency |
| RS748210737 |
ANLN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748210823 |
AIPL1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 4, Leber congenital amaurosis |
| RS748211848 |
BRIP1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS748212030 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS748212979 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748213808 |
LRRK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Parkinson disease 8, Autosomal dominant Parkinson disease 8 |
| RS748213879 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS748215343 |
OPA1
|
Health Risk |
Pathogenic |
— |
| RS748215430 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS748215576 |
IL12B
|
Health Risk |
Pathogenic/Likely pathogenic |
Mendelian susceptibility to mycobacterial diseases due to complete IL12B deficiency, IL12B-related disorder |
| RS748215651 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS748215804 |
TCTN1
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS748216114 |
MAK
|
Health Risk |
Pathogenic |
— |
| RS74821926 |
ALB
|
Health Risk |
Pathogenic |
Alloalbuminemia, Alloalbuminemia |
| RS748219640 |
AGRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 8, Inborn genetic diseases |
| RS748219689 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748219743 |
UGT1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Crigler-Najjar syndrome type 1, Inborn genetic diseases |
| RS748219780 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS748220102 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Tetralogy of Fallot |
| RS748221725 |
TMEM67
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, Meckel-Gruber syndrome |
| RS748223125 |
TNXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome due to tenascin-X deficiency, Ehlers-Danlos syndrome due to tenascin-X deficiency |
| RS748223349 |
RTEL1
|
Health Risk |
Pathogenic |
Interstitial lung disease 2, Interstitial lung disease 2 |
| RS748223473 |
ITGB4
|
Health Risk |
Likely pathogenic |
Epidermolysis bullosa, junctional 5A |
| RS748223519 |
ADAMTS13
|
Health Risk |
Pathogenic |
Thrombocytopenia, Abnormal bleeding |
| RS748225883 |
MMUT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748226232 |
MIB1
|
Health Risk |
Likely pathogenic |
MIB1-related disorder, MIB1-related disorder |
| RS748227291 |
ALG12
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG12-congenital disorder of glycosylation, Inborn genetic diseases |
| RS748227837 |
PRNP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inherited prion disease, Huntington disease-like 1 |
| RS748228253 |
UMOD
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial juvenile hyperuricemic nephropathy type 1, Familial juvenile hyperuricemic nephropathy type 1 |
| RS748228488 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748230358 |
BMPR2
|
Health Risk |
Pathogenic |
Pulmonary hypertension, primary |
| RS748232676 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
SPTAN1-related disorder, Spastic paraplegia 91 |
| RS748233107 |
JPH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS748233241 |
ABCG8
|
Health Risk |
Pathogenic |
Sitosterolemia 1, Sitosterolemia 1 |
| RS748233295 |
ABCC8
|
Health Risk |
Likely pathogenic |
Hyperinsulinemic hypoglycemia, familial |
| RS748234107 |
SRP72
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748234485 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Alstrom syndrome |
| RS748235011 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS748236037 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS748237097 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS748237572 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS748237614 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS748240234 |
PNPLA1
|
Health Risk |
Pathogenic |
— |
| RS748240670 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
PTEN hamartoma tumor syndrome, Hereditary cancer-predisposing syndrome |
| RS748240859 |
FERMT1
|
Health Risk |
Pathogenic |
Kindler syndrome, FERMT1-related disorder |
| RS748241066 |
TRIP11
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis, type IA |
| RS748241465 |
ATP2A1
|
Health Risk |
Pathogenic |
Brody myopathy, Brody myopathy |
| RS74824159 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myotonia, autosomal recessive form |
| RS748241805 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS748242385 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 5, Cardiovascular phenotype |
| RS748242735 |
PHKB
|
Health Risk |
Pathogenic |
Glycogen storage disease IXb, Glycogen storage disease IXb |
| RS748243814 |
KDM6B
|
Health Risk |
Pathogenic |
— |
| RS748244135 |
IFT172
|
Health Risk |
Pathogenic |
— |
| RS748245325 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS748246442 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS748247534 |
PHIP
|
Health Risk |
Conflicting classifications of pathogenicity |
PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome, Intellectual disability |
| RS748248022 |
COL2A1
|
Health Risk |
Pathogenic |
— |
| RS748248329 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS748248444 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS748250829 |
ALPL
|
Health Risk |
Likely pathogenic |
— |
| RS748252615 |
PRR12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748254534 |
GABRA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748254625 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Alport syndrome |
| RS748255454 |
SPG7
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS748256431 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS748256443 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome, Macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome |
| RS748256556 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS748261129 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS748262024 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spinocerebellar ataxia |