| RS748069734 |
MYO18B
|
Health Risk |
Likely pathogenic |
MYO18B-related disorder, MYO18B-related disorder |
| RS748069737 |
DOCK6
|
Health Risk |
Likely pathogenic |
— |
| RS748070271 |
TNPO3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1F, Autosomal dominant limb-girdle muscular dystrophy type 1F |
| RS748071471 |
FREM2
|
Health Risk |
Pathogenic |
— |
| RS748072057 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 9 |
| RS748072501 |
RPGRIP1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 6, Leber congenital amaurosis 6 |
| RS748074236 |
HTRA1
|
Health Risk |
Likely pathogenic |
Cerebral arteriopathy, autosomal dominant |
| RS748074364 |
BCOR
|
Health Risk |
Pathogenic |
Oculofaciocardiodental syndrome, Oculofaciocardiodental syndrome |
| RS748075089 |
GRIN2B
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 6 |
| RS748075979 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS748076639 |
SLC17A8
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 25, Autosomal dominant nonsyndromic hearing loss 25 |
| RS748076659 |
AGRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 8, Inborn genetic diseases |
| RS748077751 |
SIX6
|
Health Risk |
Likely pathogenic |
Colobomatous optic disc-macular atrophy-chorioretinopathy syndrome, Colobomatous optic disc-macular atrophy-chorioretinopathy syndrome |
| RS748077880 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS748078123 |
TNNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy 2 |
| RS748079162 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS748079943 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS748080151 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 2, Usher syndrome type 1 |
| RS748082314 |
IGF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Growth delay due to insulin-like growth factor I resistance, Growth delay due to insulin-like growth factor I resistance |
| RS748082671 |
PSMB8
|
Health Risk |
Pathogenic |
PROTEASOME-ASSOCIATED AUTOINFLAMMATORY SYNDROME 1, DIGENIC |
| RS748082803 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
GLUT1 deficiency syndrome 1, autosomal recessive |
| RS748082838 |
DNMT3A
|
Health Risk |
Pathogenic |
— |
| RS748084362 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS748084580 |
KCNV2
|
Health Risk |
Pathogenic/Likely pathogenic |
Cone dystrophy, Retinal dystrophy |
| RS748084795 |
ATP8B1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748085214 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Astrocytoma, Inborn genetic diseases |
| RS748085424 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS748086016 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1F, Usher syndrome type 1F |
| RS748086984 |
RAD50
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS748087383 |
FKRP
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2I, Walker-Warburg congenital muscular dystrophy |
| RS748087536 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS748088219 |
LIFR
|
Health Risk |
Likely pathogenic |
Stüve-Wiedemann syndrome 1, Stüve-Wiedemann syndrome 1 |
| RS748088599 |
OTOG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748089228 |
CANT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748089700 |
SDHA
|
Health Risk |
Pathogenic/Likely pathogenic |
Pheochromocytoma/paraganglioma syndrome 5, Hereditary cancer-predisposing syndrome |
| RS748089844 |
WRN
|
Health Risk |
Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS748089878 |
CEP152
|
Health Risk |
Pathogenic |
Seckel syndrome 5, Microcephaly 9 |
| RS748090019 |
IFT52
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 16 with or without polydactyly, Short-rib thoracic dysplasia 16 with or without polydactyly |
| RS748090537 |
COL27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748090636 |
MPI
|
Health Risk |
Conflicting classifications of pathogenicity |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS748091842 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS748092969 |
MORC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2Z, Charcot-Marie-Tooth disease axonal type 2Z |
| RS748093757 |
PIGO
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS748094224 |
SLC25A13
|
Health Risk |
Likely pathogenic |
Citrin deficiency, Citrullinemia |
| RS748094394 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS748094459 |
CTNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Ocular cystinosis |
| RS748095080 |
GJB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth Neuropathy X, Charcot-Marie-Tooth disease |
| RS748095129 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS748095197 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS748096417 |
RPE65
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 20, Leber congenital amaurosis 2 |
| RS748099523 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS748099677 |
LAMB3
|
Health Risk |
Pathogenic |
— |
| RS748099966 |
AUH
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria type 1, 3-methylglutaconic aciduria type 1 |
| RS748100651 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS748100852 |
HS6ST2
|
Health Risk |
Conflicting classifications of pathogenicity |
Paganini-Miozzo syndrome, Paganini-Miozzo syndrome |
| RS748101708 |
MED13L
|
Health Risk |
Likely pathogenic |
— |
| RS748102589 |
MEN1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS748102718 |
TJP2
|
Health Risk |
Conflicting classifications of pathogenicity |
TJP2-related disorder, TJP2-related disorder |
| RS748102856 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Myopathy |
| RS748103155 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 6, WFS1-Related Spectrum Disorders |
| RS748103437 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS748103983 |
CHRNE
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome, Congenital myasthenic syndrome 4A |
| RS748104371 |
RP1
|
Health Risk |
Pathogenic |
— |
| RS748104690 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS748105435 |
PLOD3
|
Health Risk |
Pathogenic/Likely pathogenic |
Bone fragility with contractures, arterial rupture |
| RS748105763 |
ACO2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748106387 |
SMARCAL1
|
Health Risk |
Pathogenic |
9 conditions, Schimke immuno-osseous dysplasia |
| RS748107948 |
PODXL
|
Health Risk |
Pathogenic |
— |
| RS748108031 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS748108904 |
MYH3
|
Health Risk |
Pathogenic |
— |
| RS74810894 |
RMRP
|
Health Risk |
Pathogenic/Likely pathogenic |
Anauxetic dysplasia, Metaphyseal chondrodysplasia |
| RS748109163 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS748109741 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748109787 |
ZIC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Holoprosencephaly 5, Holoprosencephaly 5 |
| RS748109826 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS748109934 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS748110014 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS748110745 |
ACADM
|
Health Risk |
Pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS748111134 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1G |
| RS748112446 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS748112833 |
TBK1
|
Health Risk |
Pathogenic |
Frontotemporal dementia and/or amyotrophic lateral sclerosis 4, Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 |
| RS748112905 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, 11p partial monosomy syndrome |
| RS748113748 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS748115007 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS748115066 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS748115277 |
ADAMTSL4
|
Health Risk |
Pathogenic |
ADAMTSL4-related disorder, ADAMTSL4-related disorder |
| RS748116978 |
GFM1
|
Health Risk |
Likely pathogenic |
Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1, Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 |
| RS748117291 |
ORC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meier-Gorlin syndrome 1, Meier-Gorlin syndrome 1 |
| RS748117555 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniosynostosis, nonspecific |
| RS748117872 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 17, Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss |
| RS748118576 |
DONSON
|
Health Risk |
Pathogenic |
— |
| RS748118737 |
COQ8A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS748118992 |
FANCC
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS748119565 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Ataxia-telangiectasia syndrome |
| RS748119797 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS748120166 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS748120886 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS748123071 |
JAGN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive severe congenital neutropenia due to JAGN1 deficiency, Autosomal recessive severe congenital neutropenia due to JAGN1 deficiency |
| RS748123356 |
SHANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Phelan-McDermid syndrome, Phelan-McDermid syndrome |
| RS748123444 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 3B, Duchenne muscular dystrophy |