| RS747938605 |
QARS1
|
Health Risk |
Pathogenic |
Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome, Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome |
| RS747939733 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS747939816 |
SDHA
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Mitochondrial complex II deficiency |
| RS747940150 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS747940330 |
OCA2
|
Health Risk |
Likely pathogenic |
— |
| RS74794071 |
CATSPER1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spermatogenic failure 7, Spermatogenic failure 7 |
| RS747940807 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic Pulmonary Fibrosis, Dyskeratosis congenita |
| RS747940875 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS747941115 |
AIRE
|
Health Risk |
Pathogenic/Likely pathogenic |
Polyglandular autoimmune syndrome, type 1 |
| RS747942388 |
TTN
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747943045 |
PCCA
|
Health Risk |
Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS747943621 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS747944333 |
VPS35
|
Health Risk |
Conflicting classifications of pathogenicity |
Parkinson disease 17, Parkinson disease 17 |
| RS747946229 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS747946275 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS747946828 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS747947002 |
PPM1D
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with gastrointestinal difficulties and high pain threshold, Inborn genetic diseases |
| RS747947171 |
PGAM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease type X, Glycogen storage disease type X |
| RS747947483 |
PLN
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1P, Dilated cardiomyopathy 1P |
| RS747947642 |
NTRK1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS747949207 |
TONSL
|
Health Risk |
Pathogenic |
— |
| RS747950242 |
ABCA4
|
Health Risk |
Pathogenic |
Severe early-childhood-onset retinal dystrophy, Stargardt disease 3 |
| RS747951577 |
GUCY2D
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 1, Cone-rod dystrophy 6 |
| RS747951988 |
RAD50
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747952058 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiovascular phenotype |
| RS747952317 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis syndrome |
| RS747952522 |
COL27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747953273 |
SMPD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with microcephaly, arthrogryposis |
| RS747953768 |
ALG3
|
Health Risk |
Pathogenic |
ALG3-congenital disorder of glycosylation, ALG3-congenital disorder of glycosylation |
| RS747954279 |
EYA4
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1J, Dilated cardiomyopathy 1J |
| RS747955135 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Pituitary adenoma 5 |
| RS747956260 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Polyps |
| RS747956311 |
HPD
|
Health Risk |
Pathogenic/Likely pathogenic |
Tyrosinemia type III, Hawkinsinuria |
| RS747956412 |
BCS1L
|
Health Risk |
Likely pathogenic |
Mitochondrial complex III deficiency nuclear type 1, Mitochondrial complex III deficiency nuclear type 1 |
| RS747956457 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS747956782 |
ITGA2B
|
Health Risk |
Likely pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS747956857 |
PLAA
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with progressive microcephaly, spasticity |
| RS747957553 |
DNAH11
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS747958554 |
USB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Poikiloderma with neutropenia, USB1-related disorder |
| RS747960015 |
CDHR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747961230 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS747962927 |
ACTL6B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747962998 |
MPL
|
Health Risk |
Likely pathogenic |
Congenital amegakaryocytic thrombocytopenia, Congenital amegakaryocytic thrombocytopenia |
| RS747964752 |
ADSL
|
Health Risk |
Pathogenic |
Adenylosuccinate lyase deficiency, Adenylosuccinate lyase deficiency |
| RS747965171 |
CDON
|
Health Risk |
Conflicting classifications of pathogenicity |
Holoprosencephaly 11, Inborn genetic diseases |
| RS747965344 |
NF1
|
Health Risk |
Pathogenic |
Neurofibromatosis, type 1 |
| RS747965676 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Chédiak-Higashi syndrome |
| RS747965749 |
CYP2U1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia 56 |
| RS747965765 |
ODAD2
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 23, Primary ciliary dyskinesia 23 |
| RS747967832 |
KDM6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747968386 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, Autoinflammatory syndrome |
| RS747968405 |
PCCA
|
Health Risk |
Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS747969201 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Inborn genetic diseases |
| RS747969932 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated focal cortical dysplasia type II, Tuberous sclerosis 1 |
| RS747970185 |
PDE6B
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS747971039 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS747971442 |
ROBO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Vesicoureteral reflux 2, Vesicoureteral reflux 2 |
| RS747972265 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS747972920 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747973076 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Amyotrophic lateral sclerosis type 5 |
| RS747974206 |
FANCM
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia |
| RS747974626 |
ILK
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Primary familial hypertrophic cardiomyopathy |
| RS747974933 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS747975445 |
ADAMTS3
|
Health Risk |
Pathogenic |
Hennekam lymphangiectasia-lymphedema syndrome 3, Inborn genetic diseases |
| RS747975797 |
HCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, HCN1-related disorder |
| RS747976486 |
NTRK1
|
Health Risk |
Pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS747978443 |
IL2RB
|
Health Risk |
Likely pathogenic |
— |
| RS747978928 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS747980515 |
CCDC39
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 14 |
| RS747980975 |
ALPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypophosphatasia, Hypophosphatasia |
| RS747981483 |
IDUA
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS747983616 |
BCHE
|
Health Risk |
Likely pathogenic |
Deficiency of butyrylcholinesterase, Deficiency of butyrylcholinesterase |
| RS747984529 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, SGCA-related disorder |
| RS747985440 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neuroblastoma |
| RS747985669 |
HADHA
|
Health Risk |
Pathogenic/Likely pathogenic |
Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency, Mitochondrial trifunctional protein deficiency |
| RS747989049 |
F7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital factor VII deficiency, Congenital factor VII deficiency |
| RS747989932 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS747990127 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS747990150 |
ZNF462
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747990896 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747990992 |
PPM1D
|
Health Risk |
Likely pathogenic |
— |
| RS747992951 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747993448 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS747993489 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS747993775 |
CPAP
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly 6, primary |
| RS747994845 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS74799487 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS747995413 |
RNASEH2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 2, Inborn genetic diseases |
| RS747995562 |
PRDM12
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital insensitivity to pain-hypohidrosis syndrome, Inborn genetic diseases |
| RS747995722 |
TYR
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 1A, SKIN/HAIR/EYE PIGMENTATION 3 |
| RS747996482 |
ISCA2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS74799832 |
RET
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple endocrine neoplasia type 2B, Thyroid carcinoma |
| RS747998566 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Emery-Dreifuss muscular dystrophy 2 |
| RS748000458 |
FANCI
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group I, Fanconi anemia |
| RS748001988 |
DIS3L2
|
Health Risk |
Pathogenic |
Perlman syndrome, Perlman syndrome |
| RS748003452 |
FANCI
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group I |
| RS748004231 |
AAAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Glucocorticoid deficiency with achalasia, Glucocorticoid deficiency with achalasia |
| RS748005072 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS748005137 |
ZCCHC8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS748005374 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |