CDAN1 Chromosome 15
Codanin 1
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What This Gene Does
This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis. [provided by RefSeq, Jul 2009]
Associated Conditions (13)
Congenital dyserythropoietic anemia
type I
CDAN1-related disorder
Anemia
congenital dyserythropoietic
type 1a
Inborn genetic diseases
Acute myeloid leukemia
Clear cell carcinoma of kidney
Colorectal cancer
Familial cancer of breast
Sarcoma
Uterine corpus endometrial carcinoma
Key Variants
RS1055175847
Conflicting classifications of pathogenicity
Health Risk
RS1320661924
Conflicting classifications of pathogenicity
Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia
Health Risk
RS138334226
Conflicting classifications of pathogenicity
Congenital dyserythropoietic anemia, type I, CDAN1-related disorder
Health Risk
RS1384797283
Conflicting classifications of pathogenicity
Health Risk
RS138839403
Conflicting classifications of pathogenicity
Congenital dyserythropoietic anemia, type I, Inborn genetic diseases
Health Risk
RS140014115
Conflicting classifications of pathogenicity
Congenital dyserythropoietic anemia, type I, Anemia
Health Risk
RS141304487
Conflicting classifications of pathogenicity
Inborn genetic diseases, Anemia, congenital dyserythropoietic
Health Risk
RS141626745
Conflicting classifications of pathogenicity
Anemia, congenital dyserythropoietic, type 1a
Health Risk
RS141832648
Conflicting classifications of pathogenicity
Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia
Health Risk
RS143086237
Conflicting classifications of pathogenicity
Anemia, congenital dyserythropoietic, type 1a
Health Risk
RS145050561
Conflicting classifications of pathogenicity
Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia
Health Risk
RS1460194406
Conflicting classifications of pathogenicity
Health Risk
All Variants (85)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS1055175847 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1320661924 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS138334226 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, CDAN1-related disorder |
| RS1384797283 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS138839403 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Inborn genetic diseases |
| RS140014115 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS141304487 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Anemia, congenital dyserythropoietic |
| RS141626745 | Health Risk | Conflicting classifications of pathogenicity | Anemia, congenital dyserythropoietic, type 1a |
| RS141832648 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS143086237 | Health Risk | Conflicting classifications of pathogenicity | Anemia, congenital dyserythropoietic, type 1a |
| RS145050561 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS1460194406 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS146049960 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS146289653 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS147426809 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, CDAN1-related disorder |
| RS148759214 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS148994527 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS149472555 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS150418267 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS150438471 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, CDAN1-related disorder |
| RS150657573 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS190314153 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS192268080 | Health Risk | Conflicting classifications of pathogenicity | Anemia, congenital dyserythropoietic, type 1a |
| RS199780617 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS200290322 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS200401359 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS200767055 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Acute myeloid leukemia |
| RS201057681 | Health Risk | Conflicting classifications of pathogenicity | Anemia, congenital dyserythropoietic, type 1a |
| RS201125492 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS201733620 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS370757859 | Health Risk | Conflicting classifications of pathogenicity | Anemia, congenital dyserythropoietic, type 1a |
| RS371799686 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS372645598 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS372671684 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Sarcoma |
| RS372998688 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Familial cancer of breast |
| RS375128684 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS377342875 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS543791953 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS565510675 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Anemia, congenital dyserythropoietic |
| RS61746359 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS749464836 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS757508400 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS764432820 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS770414676 | Health Risk | Conflicting classifications of pathogenicity | Anemia, congenital dyserythropoietic, type 1a |
| RS772157159 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Anemia |
| RS772828912 | Health Risk | Conflicting classifications of pathogenicity | Anemia, congenital dyserythropoietic, type 1a |
| RS774076440 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS945794101 | Health Risk | Conflicting classifications of pathogenicity | Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia |
| RS120074166 | Health Risk | Likely pathogenic | Congenital dyserythropoietic anemia, type I, Anemia |
| RS1371457965 | Health Risk | Likely pathogenic | — |