CDAN1 Chromosome 15

Codanin 1
85 variants 85 Health Risk

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What This Gene Does
This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis. [provided by RefSeq, Jul 2009]
Associated Conditions (13)
Congenital dyserythropoietic anemia
type I
CDAN1-related disorder
Anemia
congenital dyserythropoietic
type 1a
Inborn genetic diseases
Acute myeloid leukemia
Clear cell carcinoma of kidney
Colorectal cancer
Familial cancer of breast
Sarcoma
Uterine corpus endometrial carcinoma
Key Variants
All Variants (85)
RSID Category Clinical Significance Conditions
RS140334403 Health Risk Likely pathogenic Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia
RS1555414654 Health Risk Likely pathogenic
RS2140490467 Health Risk Likely pathogenic
RS2506064523 Health Risk Likely pathogenic
RS2506067560 Health Risk Likely pathogenic Anemia, congenital dyserythropoietic, type 1a
RS2506092231 Health Risk Likely pathogenic Anemia, congenital dyserythropoietic, type 1a
RS2506131342 Health Risk Likely pathogenic Anemia, congenital dyserythropoietic, type 1a
RS2506137543 Health Risk Likely pathogenic Anemia, congenital dyserythropoietic, type 1a
RS778173860 Health Risk Likely pathogenic Anemia, congenital dyserythropoietic, type 1a
RS120074168 Health Risk Pathogenic Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia
RS120074169 Health Risk Pathogenic Congenital dyserythropoietic anemia, type I, Congenital dyserythropoietic anemia
RS1223300626 Health Risk Pathogenic
RS1336651679 Health Risk Pathogenic Anemia, congenital dyserythropoietic, type 1a
RS1383200463 Health Risk Pathogenic Anemia, congenital dyserythropoietic, type 1a
RS145148854 Health Risk Pathogenic Uterine corpus endometrial carcinoma, Uterine corpus endometrial carcinoma
RS1566989338 Health Risk Pathogenic
RS2061523666 Health Risk Pathogenic
RS2061548697 Health Risk Pathogenic
RS2140471687 Health Risk Pathogenic Anemia, congenital dyserythropoietic, type 1a
RS2140505826 Health Risk Pathogenic Anemia, congenital dyserythropoietic, type 1a
RS2506077768 Health Risk Pathogenic
RS2506082363 Health Risk Pathogenic
RS2506085601 Health Risk Pathogenic
RS2506088522 Health Risk Pathogenic
RS2506101144 Health Risk Pathogenic Anemia, congenital dyserythropoietic, type 1a
RS2506128866 Health Risk Pathogenic
RS375339408 Health Risk Pathogenic Anemia, congenital dyserythropoietic, type 1a
RS762178142 Health Risk Pathogenic
RS769679860 Health Risk Pathogenic
RS778822407 Health Risk Pathogenic Anemia, congenital dyserythropoietic, type 1a
RS120074167 Health Risk Pathogenic/Likely pathogenic Congenital dyserythropoietic anemia, type I, Anemia
RS80338694 Health Risk Pathogenic/Likely pathogenic Anemia, congenital dyserythropoietic, type 1a
RS80338696 Health Risk Pathogenic/Likely pathogenic Congenital dyserythropoietic anemia, type I, Anemia
RS80338697 Health Risk Pathogenic/Likely pathogenic Congenital dyserythropoietic anemia, type I, Anemia
RS80338699 Health Risk Pathogenic/Likely pathogenic Congenital dyserythropoietic anemia, type I, Anemia
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