| RS747447584 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS747447840 |
ADAMTS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS747448946 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Arrhythmogenic right ventricular dysplasia 8 |
| RS747449574 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS747449879 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS747449936 |
DHX37
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747450377 |
TMEM165
|
Health Risk |
Conflicting classifications of pathogenicity |
TMEM165-congenital disorder of glycosylation, TMEM165-congenital disorder of glycosylation |
| RS747450518 |
FANCD2
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS747453069 |
OXCT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Succinyl-CoA acetoacetate transferase deficiency, Succinyl-CoA acetoacetate transferase deficiency |
| RS747453876 |
PAX2
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal coloboma syndrome, Focal segmental glomerulosclerosis 7 |
| RS747454154 |
UPB1
|
Health Risk |
Likely pathogenic |
— |
| RS747454971 |
OPA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Uterine corpus endometrial carcinoma, Uterine corpus endometrial carcinoma |
| RS747456938 |
F5
|
Health Risk |
Conflicting classifications of pathogenicity |
Budd-Chiari syndrome, Factor V deficiency |
| RS747457022 |
GDAP2
|
Health Risk |
Likely pathogenic |
GDAP2-related disorder, GDAP2-related disorder |
| RS747457090 |
ASAH1
|
Health Risk |
Pathogenic |
Ovarian serous cystadenocarcinoma, Ovarian serous cystadenocarcinoma |
| RS747457929 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS747458532 |
MYO3A
|
Health Risk |
Likely pathogenic |
— |
| RS747458590 |
HPGD
|
Health Risk |
Pathogenic |
— |
| RS747458739 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, NEB-related disorder |
| RS747459337 |
AP3B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 2, Hermansky-Pudlak syndrome 2 |
| RS747459594 |
ADGRE2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747461754 |
SUOX
|
Health Risk |
Pathogenic |
Sulfite oxidase deficiency, Sulfite oxidase deficiency |
| RS747462107 |
NBN
|
Health Risk |
Pathogenic |
Microcephaly, normal intelligence and immunodeficiency |
| RS747463080 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS747463968 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary diffuse gastric adenocarcinoma |
| RS747464117 |
LRBA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to LRBA deficiency, Inborn genetic diseases |
| RS747464195 |
IL36RN
|
Health Risk |
Pathogenic |
Generalized pustular psoriasis, Generalized pustular psoriasis |
| RS747464249 |
SPEG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747466300 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Kabuki syndrome |
| RS747467294 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS747467877 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Cardiovascular phenotype |
| RS747468547 |
PPP1CB
|
Health Risk |
Conflicting classifications of pathogenicity |
PPP1CB-related disorder, PPP1CB-related disorder |
| RS747469176 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS747469275 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747469438 |
FANCD2
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS747469885 |
TRNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome, Inborn genetic diseases |
| RS747470305 |
DHX37
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747470831 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial meningioma |
| RS747471303 |
OTOF
|
Health Risk |
Pathogenic/Likely pathogenic |
Nonsyndromic genetic hearing loss, Nonsyndromic genetic hearing loss |
| RS747472065 |
CAMK2B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747473434 |
TSEN54
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747475323 |
EIF2B5
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS747475412 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747475542 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747475869 |
CYFIP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 65 |
| RS747476158 |
GMPPA
|
Health Risk |
Likely pathogenic |
GMPPA-related disorder, GMPPA-related disorder |
| RS747476251 |
HADH
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of 3-hydroxyacyl-CoA dehydrogenase, Hyperinsulinemic hypoglycemia |
| RS747476629 |
EYA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Branchiootorenal syndrome 1, Otofaciocervical syndrome 1 |
| RS747476726 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS747476940 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747477628 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
WFS1-Related Spectrum Disorders, Autosomal dominant nonsyndromic hearing loss 6 |
| RS747478031 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 36 |
| RS747479318 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS747479565 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperkalemic periodic paralysis, Potassium-aggravated myotonia |
| RS747479664 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS747480084 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS747480526 |
TUBB3
|
Health Risk |
Pathogenic/Likely pathogenic |
Complex cortical dysplasia with other brain malformations 1, Inborn genetic diseases |
| RS747481280 |
OPTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Motor neuron disease, Primary open angle glaucoma |
| RS747481987 |
SLC34A3
|
Health Risk |
Pathogenic |
— |
| RS747483177 |
SPAG1
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia 28 |
| RS747483368 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic liver disease 1, Polycystic kidney disease |
| RS747483450 |
PIK3CD
|
Health Risk |
Pathogenic |
Immunodeficiency 14, Immunodeficiency 14 |
| RS747483671 |
PCNT
|
Health Risk |
Likely pathogenic |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS747485058 |
AGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS747485179 |
SEMA3A
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS747486328 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS747486855 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS747488464 |
CTNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Ocular cystinosis, Juvenile nephropathic cystinosis |
| RS747488546 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile hypophosphatasia, Adult hypophosphatasia |
| RS747489126 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS747489303 |
CACNA2D4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747489687 |
MCPH1
|
Health Risk |
Pathogenic |
— |
| RS747490039 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Cardiomyopathy |
| RS747490958 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 1, Perry syndrome |
| RS747493127 |
HSPG2
|
Health Risk |
Pathogenic |
HSPG2-related disorder, HSPG2-related disorder |
| RS747493997 |
POMT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A2 |
| RS747495987 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS747496165 |
GNE
|
Health Risk |
Likely pathogenic |
GNE myopathy, Sialuria |
| RS747496610 |
CRTAP
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type 7, Osteogenesis imperfecta type 7 |
| RS747496798 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked intellectual disability, Cantagrel type |
| RS747497458 |
DIS3L2
|
Health Risk |
Likely pathogenic |
Perlman syndrome, Familial cancer of breast |
| RS747498968 |
BLM
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Bloom syndrome |
| RS747499304 |
MMAB
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria, cblB type |
| RS747499674 |
COL9A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747500641 |
CACNA2D1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brugada syndrome |
| RS747501109 |
TRIP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Clark-Baraitser syndrome, Clark-Baraitser syndrome |
| RS747501465 |
SETX
|
Health Risk |
Pathogenic/Likely pathogenic |
Spinocerebellar ataxia, autosomal recessive |
| RS747502205 |
PAX3
|
Health Risk |
Conflicting classifications of pathogenicity |
Waardenburg syndrome, Craniofacial-deafness-hand syndrome |
| RS747502487 |
NOS3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747502723 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, NOTCH1-related disorder |
| RS747503698 |
SPG7
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 7, SPG7-related disorder |
| RS747504060 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS747504082 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS747504380 |
PKP2
|
Health Risk |
Pathogenic |
Arrhythmogenic right ventricular dysplasia 9, Arrhythmogenic right ventricular dysplasia 9 |
| RS747504492 |
MSH2
|
Health Risk |
Pathogenic |
Lynch syndrome, Hereditary cancer-predisposing syndrome |
| RS747504576 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS747504631 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS747505929 |
KDM6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 2, KDM6A-related disorder |
| RS747505958 |
IL11RA
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS747505977 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |