| RS747258045 |
CNGB1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747259064 |
ADAM22
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 61 |
| RS747260038 |
PTS
|
Health Risk |
Pathogenic |
6-Pyruvoyl-tetrahydrobiopterin synthase deficiency, 6-Pyruvoyl-tetrahydrobiopterin synthase deficiency |
| RS747261340 |
SYNJ1
|
Health Risk |
Pathogenic |
Early-onset Parkinson disease 20, Developmental and epileptic encephalopathy |
| RS747262065 |
MAN1B1
|
Health Risk |
Pathogenic |
Rafiq syndrome, Rafiq syndrome |
| RS747262113 |
HOXA13
|
Health Risk |
Conflicting classifications of pathogenicity |
HOXA13-related disorder, Guttmacher syndrome |
| RS74726213 |
SIM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oromandibular-limb hypogenesis spectrum, Obesity due to SIM1 deficiency |
| RS747262651 |
TPK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Childhood encephalopathy due to thiamine pyrophosphokinase deficiency, Childhood encephalopathy due to thiamine pyrophosphokinase deficiency |
| RS747263275 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS747265823 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS747266069 |
TRIM32
|
Health Risk |
Pathogenic |
Sarcotubular myopathy, Bardet-Biedl syndrome |
| RS747266387 |
P2RX2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747267404 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS747267907 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747268471 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS747269745 |
FBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fructose-biphosphatase deficiency, Fructose-biphosphatase deficiency |
| RS747270146 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia |
| RS747270555 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS747271385 |
PHYH
|
Health Risk |
Likely pathogenic |
Phytanic acid storage disease, Phytanic acid storage disease |
| RS747271394 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiovascular phenotype |
| RS747271930 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS747272462 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia type 4 |
| RS747272625 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Cardiovascular phenotype |
| RS747272786 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 3 |
| RS747273828 |
IVD
|
Health Risk |
Pathogenic/Likely pathogenic |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS747274181 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS747274874 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747274959 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS747275587 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiomyopathy |
| RS747275658 |
ARG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Arginase deficiency, Arginase deficiency |
| RS747275713 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747276038 |
TK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747277541 |
KIAA0586
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 23, Short-rib thoracic dysplasia 14 with polydactyly |
| RS747277579 |
TTBK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747279627 |
OTX2
|
Health Risk |
Pathogenic |
Syndromic microphthalmia type 5, OTX2-related disorder |
| RS747281324 |
BLM
|
Health Risk |
Likely pathogenic |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS747281440 |
PRMT9
|
Health Risk |
Pathogenic |
Neurodevelopmental abnormality, Neurodevelopmental abnormality |
| RS747282057 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS747282707 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS747283283 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Alternating hemiplegia of childhood 1 |
| RS747283967 |
PIGN
|
Health Risk |
Pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 1, Multiple congenital anomalies-hypotonia-seizures syndrome 1 |
| RS747284213 |
FIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease |
| RS747284477 |
SELENON
|
Health Risk |
Pathogenic |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS747284663 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS747284798 |
GBA1
|
Health Risk |
Likely pathogenic |
Gaucher disease, Gaucher disease type I |
| RS747285235 |
SIGMAR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive distal spinal muscular atrophy 2, Amyotrophic lateral sclerosis type 16 |
| RS747285262 |
AGTPBP1
|
Health Risk |
Likely pathogenic |
Neurodegeneration, childhood-onset |
| RS747286271 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS747286444 |
TTN
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1G, Dilated cardiomyopathy 1G |
| RS747287311 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS747288279 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked Alport syndrome, COL4A5-related disorder |
| RS747288455 |
STXBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS747288805 |
FBLN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa, Macular degeneration |
| RS747289205 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS747289468 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS747289672 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual developmental disorder with autism and macrocephaly |
| RS747289875 |
DES
|
Health Risk |
Conflicting classifications of pathogenicity |
Desmin-related myofibrillar myopathy, Desmin-related myofibrillar myopathy |
| RS747290752 |
DNAAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 10, Primary ciliary dyskinesia |
| RS747291227 |
JARID2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS747291494 |
GAN
|
Health Risk |
Pathogenic/Likely pathogenic |
Giant axonal neuropathy 1, Inborn genetic diseases |
| RS747291682 |
FANCI
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group I, Fanconi anemia |
| RS747291865 |
ACADSB
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of 2-methylbutyryl-CoA dehydrogenase, Deficiency of 2-methylbutyryl-CoA dehydrogenase |
| RS747292260 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747294604 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747297291 |
BSCL2
|
Health Risk |
Likely pathogenic |
Congenital generalized lipodystrophy type 2, Congenital generalized lipodystrophy type 2 |
| RS747298346 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS747298351 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Inborn genetic diseases |
| RS747299117 |
CHD3
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS747300179 |
FAH
|
Health Risk |
Likely pathogenic |
Tyrosinemia type I, Tyrosinemia type I |
| RS747301279 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS747301309 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747301529 |
FLG
|
Health Risk |
Pathogenic |
Dermatitis, atopic |
| RS747301663 |
D2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
D-2-hydroxyglutaric aciduria 1, Inborn genetic diseases |
| RS747301994 |
COL17A1
|
Health Risk |
Pathogenic |
— |
| RS747302288 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary breast ovarian cancer syndrome |
| RS747302299 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747303076 |
MTRR
|
Health Risk |
Likely pathogenic |
Neural tube defects, folate-sensitive |
| RS747303322 |
HMOX1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747304080 |
DST
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary sensory and autonomic neuropathy type 6, Epidermolysis bullosa simplex 3 |
| RS747305045 |
CP
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of ferroxidase, Deficiency of ferroxidase |
| RS747305214 |
ZNF408
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747305733 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS747305746 |
TP63
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, TP63-Related Spectrum Disorders |
| RS747306849 |
MCM3AP
|
Health Risk |
Conflicting classifications of pathogenicity |
Peripheral neuropathy, autosomal recessive |
| RS747310070 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 12 |
| RS747310967 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS747311061 |
IARS1
|
Health Risk |
Pathogenic |
Growth retardation, intellectual developmental disorder |
| RS747311078 |
DNAAF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS747312156 |
PHIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PHIP-related disorder |
| RS747312241 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Dystonia 27 |
| RS747312255 |
DRD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dystonic disorder, Dystonic disorder |
| RS747312867 |
AARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747313011 |
AARS2
|
Health Risk |
Pathogenic |
AARS2-related disorder, AARS2-related disorder |
| RS74731340 |
GBA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gaucher disease type I, Gaucher disease type II |
| RS747313972 |
SALL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Oculootoradial syndrome |
| RS747315554 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS747316677 |
GUF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 40 |
| RS747317429 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Hereditary cancer |
| RS747317946 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS747318789 |
LMBRD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria and homocystinuria type cblF, Methylmalonic aciduria and homocystinuria type cblF |