| RS747196387 |
BCHE
|
Health Risk |
Likely pathogenic |
Deficiency of butyrylcholinesterase, Deficiency of butyrylcholinesterase |
| RS747196571 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS747197324 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS747197522 |
SGSH
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-A |
| RS747198089 |
SDHB
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary pheochromocytoma and paraganglioma |
| RS747198298 |
MPI
|
Health Risk |
Pathogenic/Likely pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS747198710 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, 6 conditions |
| RS747199032 |
GNE
|
Health Risk |
Pathogenic |
GNE myopathy, Sialuria |
| RS747201171 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS747202772 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747203627 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 4, Fibromatosis |
| RS747203787 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747204355 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747204624 |
PPT1
|
Health Risk |
Likely pathogenic |
Neuronal ceroid lipofuscinosis 1, Neuronal ceroid lipofuscinosis 1 |
| RS747205016 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS747205109 |
MYF6
|
Health Risk |
Likely pathogenic |
— |
| RS747205797 |
RERE
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747208140 |
VAPB
|
Health Risk |
Conflicting classifications of pathogenicity |
Adult-onset proximal spinal muscular atrophy, autosomal dominant |
| RS747208674 |
CNTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial adult myoclonic |
| RS747209331 |
COL7A1
|
Health Risk |
Pathogenic |
— |
| RS74720958 |
EYA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Otofaciocervical syndrome 1, Melnick-Fraser syndrome |
| RS747210644 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS747213800 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS747214029 |
LRBA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to LRBA deficiency, Combined immunodeficiency due to LRBA deficiency |
| RS747214324 |
MMACHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Disorders of Intracellular Cobalamin Metabolism, Cobalamin C disease |
| RS747214372 |
BRIP1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS747214463 |
LIPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Lysosomal acid lipase deficiency, Wolman disease |
| RS747214535 |
OCA2
|
Health Risk |
Likely pathogenic |
Oculocutaneous albinism, SKIN/HAIR/EYE PIGMENTATION 1 |
| RS747214551 |
HSD17B4
|
Health Risk |
Conflicting classifications of pathogenicity |
Bifunctional peroxisomal enzyme deficiency, Perrault syndrome |
| RS747214620 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS747215273 |
F5
|
Health Risk |
Pathogenic |
Congenital factor V deficiency, Congenital factor V deficiency |
| RS747216258 |
PEX5
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 2B, Peroxisome biogenesis disorder 2B |
| RS747217399 |
VPS13B
|
Health Risk |
Pathogenic/Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS747217677 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS747219934 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Congenital contractural arachnodactyly |
| RS747220413 |
SPG11
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS747222233 |
SERPINF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Osteogenesis imperfecta |
| RS747222651 |
TCF12
|
Health Risk |
Pathogenic/Likely pathogenic |
TCF12-related craniosynostosis, TCF12-related craniosynostosis |
| RS747223076 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747223436 |
EYA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 10, Congestive heart failure |
| RS747223735 |
SMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type A |
| RS747224013 |
MAGEB2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747224934 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747225246 |
LZTR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS747225625 |
MCM3AP
|
Health Risk |
Conflicting classifications of pathogenicity |
Peripheral neuropathy, autosomal recessive |
| RS747226226 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747227352 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS747228052 |
PRSS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS747228795 |
NDUFAF5
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 16 |
| RS747229048 |
SLC12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 1, Bartter syndrome |
| RS747229863 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS747229909 |
CLN6
|
Health Risk |
Likely pathogenic |
Neuronal ceroid lipofuscinosis, Ceroid lipofuscinosis |
| RS747229979 |
PLCE1
|
Health Risk |
Likely pathogenic |
Nephrotic syndrome, PLCE1-related disorder |
| RS747231282 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS747231434 |
EYA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Melnick-Fraser syndrome, Branchiootic syndrome 1 |
| RS747231463 |
GLE1
|
Health Risk |
Pathogenic |
— |
| RS747231741 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS747233125 |
CCDC40
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Combined immunodeficiency due to DOCK8 deficiency |
| RS747233148 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS747234596 |
F2
|
Health Risk |
Likely pathogenic |
Congenital prothrombin deficiency, Congenital prothrombin deficiency |
| RS747234651 |
PTCH1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS747236787 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747237113 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cortical tubers, Tuberous sclerosis 2 |
| RS747238010 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Familial hemiplegic migraine |
| RS747238231 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS747239076 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS747239148 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS747239403 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Papillary renal cell carcinoma type 1, Hereditary cancer-predisposing syndrome |
| RS747240394 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS747240928 |
HGSNAT
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS747241884 |
NF1
|
Health Risk |
Pathogenic |
— |
| RS747242422 |
GIPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 15, Autosomal recessive nonsyndromic hearing loss 15 |
| RS747243608 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747244348 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 12 |
| RS747244814 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Dextro-looped transposition of the great arteries, Inborn genetic diseases |
| RS747246700 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 4, Nephronophthisis 12 |
| RS747247583 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial restrictive cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747247646 |
GLI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Holoprosencephaly 9, Postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome |
| RS747247743 |
PC
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate carboxylase deficiency, Pyruvate carboxylase deficiency |
| RS747247971 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS747248100 |
CYP11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Corticosterone methyloxidase type 2 deficiency, Glucocorticoid-remediable aldosteronism |
| RS747248488 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS747249619 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS747249702 |
NDUFS1
|
Health Risk |
Likely pathogenic |
Leigh syndrome, Leigh syndrome |
| RS747249958 |
AFG2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental delay, SPATA5L1-related disorder |
| RS747249998 |
SDHA
|
Health Risk |
Pathogenic |
Pheochromocytoma/paraganglioma syndrome 5, Mitochondrial complex II deficiency |
| RS747250117 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome, Microangiopathy and leukoencephalopathy |
| RS747251435 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS747252798 |
MOCOS
|
Health Risk |
Conflicting classifications of pathogenicity |
Xanthinuria type II, Xanthinuria type II |
| RS747252861 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS747253294 |
FANCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group L |
| RS747255117 |
ABCB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestasis, intrahepatic |
| RS747256043 |
YRDC
|
Health Risk |
Pathogenic |
Galloway-Mowat syndrome 10, Galloway-Mowat syndrome 10 |
| RS747256476 |
KMT2C
|
Health Risk |
Pathogenic |
KMT2C-related NDD, KMT2C-related NDD |
| RS747256664 |
CDH1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS747256929 |
RAB11B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747257110 |
SLC25A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Citrin deficiency, SLC25A13-related disorder |
| RS747257199 |
TCN2
|
Health Risk |
Pathogenic |
Transcobalamin II deficiency, Transcobalamin II deficiency |
| RS747257567 |
RDH12
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Leber congenital amaurosis 13 |
| RS747257894 |
POLR3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukodystrophy, Leukodystrophy |