| RS747068091 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Desmin-related myofibrillar myopathy, Dilated cardiomyopathy 1G |
| RS747068278 |
TIA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Welander distal myopathy, Welander distal myopathy |
| RS747068538 |
CYP2U1;CYP2U1-AS1
|
Health Risk |
Likely pathogenic |
— |
| RS747068627 |
MPDZ
|
Health Risk |
Pathogenic/Likely pathogenic |
Hydrocephalus, nonsyndromic |
| RS747069454 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 2 |
| RS747070579 |
BRCA2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS747072217 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Periventricular nodular heterotopia 7, Periventricular nodular heterotopia 7 |
| RS747072227 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS747072310 |
EMP2
|
Health Risk |
Likely pathogenic |
Nephrotic syndrome, type 10 |
| RS747072478 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, PTEN hamartoma tumor syndrome |
| RS747073806 |
NXF5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747073940 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS747074044 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS747076316 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS747076390 |
MYPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1KK, Cardiovascular phenotype |
| RS747076541 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS747077612 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
BENTA disease, Severe combined immunodeficiency due to CARD11 deficiency |
| RS747077717 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747078316 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 5 |
| RS747079285 |
DNM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Developmental and epileptic encephalopathy, 31A |
| RS747079903 |
CEP250
|
Health Risk |
Likely pathogenic |
— |
| RS747080824 |
GARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS747081586 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS747081862 |
COL7A1
|
Health Risk |
Likely pathogenic |
Recessive dystrophic epidermolysis bullosa, Recessive dystrophic epidermolysis bullosa |
| RS747082615 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, CHARGE syndrome |
| RS747082651 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS747083495 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome |
| RS747083748 |
HMOX1
|
Health Risk |
Pathogenic |
Heme oxygenase 1 deficiency, Uterine carcinosarcoma |
| RS747084358 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS747084700 |
SIX5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747084709 |
CDK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial melanoma |
| RS747086776 |
SCN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial infantile |
| RS747088640 |
NEUROG3
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital malabsorptive diarrhea 4, Congenital malabsorptive diarrhea 4 |
| RS747089219 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747089235 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS747091524 |
DNAAF19
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 17 |
| RS747091795 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS747091800 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Inborn genetic diseases |
| RS747092381 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Periventricular nodular heterotopia 7, Periventricular nodular heterotopia 7 |
| RS747093000 |
GNAS
|
Health Risk |
Conflicting classifications of pathogenicity |
GNAS-related disorder, GNAS-related disorder |
| RS747093389 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS747093432 |
FYCO1
|
Health Risk |
Pathogenic |
Cataract 18, Cataract 18 |
| RS747093483 |
SDHC
|
Health Risk |
Conflicting classifications of pathogenicity |
Pheochromocytoma/paraganglioma syndrome 3, Gastrointestinal stromal tumor |
| RS747094191 |
POC1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome, Short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome |
| RS747094879 |
PABPC1L
|
Health Risk |
Likely pathogenic |
Inherited oocyte maturation defect, Inherited oocyte maturation defect |
| RS747095250 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1B, Autosomal dominant nonsyndromic hearing loss 11 |
| RS747095957 |
TYR
|
Health Risk |
Likely pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1A |
| RS747097352 |
NEU1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS747097789 |
GJA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cataract 14 multiple types, Inborn genetic diseases |
| RS747097960 |
PKLR
|
Health Risk |
Likely pathogenic |
Pyruvate kinase deficiency of red cells, Pyruvate kinase deficiency of red cells |
| RS747099919 |
PEX12
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder type 3B, Peroxisome biogenesis disorder 3A (Zellweger) |
| RS747100254 |
NF1
|
Health Risk |
Pathogenic |
Neurofibromatosis, type 1 |
| RS747100389 |
RAD9B
|
Health Risk |
Likely pathogenic |
Neural tube defect, Neural tube defect |
| RS747101350 |
NDUFA12
|
Health Risk |
Pathogenic |
Mitochondrial complex I deficiency, nuclear type 23 |
| RS747101853 |
BPTF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies, Inborn genetic diseases |
| RS747103340 |
CUL7
|
Health Risk |
Pathogenic |
— |
| RS747103920 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS747104789 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Familial thoracic aortic aneurysm and aortic dissection |
| RS747104864 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS747104878 |
SNTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS747105829 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder, Inborn genetic diseases |
| RS747106242 |
TRIP11
|
Health Risk |
Pathogenic |
Achondrogenesis, type IA |
| RS747107966 |
ADA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of adenosine deaminase 2, Autoinflammatory syndrome |
| RS747108004 |
SZT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747108035 |
CHAT
|
Health Risk |
Likely pathogenic |
Familial infantile myasthenia, Familial infantile myasthenia |
| RS747108452 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS747108471 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747108670 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Charcot-Marie-Tooth disease dominant intermediate B |
| RS747108820 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS747108904 |
HNRNPU
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 54 |
| RS747109352 |
MYLK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 1, Hypertrophic cardiomyopathy 1 |
| RS747109385 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS747109506 |
WDR73
|
Health Risk |
Conflicting classifications of pathogenicity |
Galloway-Mowat syndrome 1, Galloway-Mowat syndrome 1 |
| RS747109742 |
MOGS
|
Health Risk |
Likely pathogenic |
MOGS-congenital disorder of glycosylation, MOGS-congenital disorder of glycosylation |
| RS747110409 |
NBAS
|
Health Risk |
Pathogenic |
— |
| RS747111841 |
HTT
|
Health Risk |
Likely pathogenic |
— |
| RS747111881 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS747113644 |
FANCE
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS747113965 |
NFKB2
|
Health Risk |
Likely pathogenic |
NFKB2-related disorder, NFKB2-related disorder |
| RS747114420 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS747114776 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hyperaldosteronism |
| RS747115338 |
SEMA6B
|
Health Risk |
Pathogenic |
See cases, See cases |
| RS747116196 |
SCNN1B
|
Health Risk |
Pathogenic/Likely pathogenic |
Bronchiectasis with or without elevated sweat chloride 1, Pseudohypoaldosteronism |
| RS747116308 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS747116356 |
ITGB3
|
Health Risk |
Likely pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS747117082 |
NHLRC2
|
Health Risk |
Likely pathogenic |
See cases, See cases |
| RS747118105 |
CLCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747118425 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747119727 |
PI4KA
|
Health Risk |
Likely pathogenic |
Polymicrogyria, perisylvian |
| RS747119819 |
VPS35L
|
Health Risk |
Pathogenic |
Ritscher-Schinzel syndrome 3, Ritscher-Schinzel syndrome 3 |
| RS747121305 |
DNAI1
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, DNAI1-related disorder |
| RS747122485 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS747122599 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747122703 |
BARD1
|
Health Risk |
Likely pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS747122876 |
RPE65
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 2, Retinitis pigmentosa |
| RS747123680 |
DNAH8
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS747125633 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS747126561 |
ARHGAP31
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 1, Adams-Oliver syndrome 1 |
| RS747127624 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS747129906 |
POMT1
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2K, Walker-Warburg congenital muscular dystrophy |