| RS746939887 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS746941221 |
CARNS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746943281 |
KIF7
|
Health Risk |
Conflicting classifications of pathogenicity |
Acrocallosal syndrome, Multiple epiphyseal dysplasia |
| RS746943696 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS746943889 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS746944448 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS746945124 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Familial thoracic aortic aneurysm and aortic dissection |
| RS746945284 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS746947861 |
TBX22
|
Health Risk |
Conflicting classifications of pathogenicity |
Cleft palate with or without ankyloglossia, X-linked |
| RS74694805 |
CTSA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined deficiency of sialidase AND beta galactosidase, Combined deficiency of sialidase AND beta galactosidase |
| RS746949078 |
LZTR1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS746949187 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS746949236 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 14, Senior-Loken syndrome 6 |
| RS746949976 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS746950373 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS746951044 |
CRELD1
|
Health Risk |
Pathogenic |
Congenital heart defects, multiple types |
| RS746952369 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RAI1-related disorder |
| RS746952638 |
TPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Cardiomyopathy |
| RS746953076 |
FBXO11
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, FBXO11-related disorder |
| RS746953590 |
FDXR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Auditory neuropathy-optic atrophy syndrome |
| RS746953932 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS746954414 |
SCN3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 7, Cardiovascular phenotype |
| RS746954557 |
DMXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746954804 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746956869 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1G |
| RS746956979 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1HH, Myofibrillar myopathy 6 |
| RS746959386 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS746960051 |
ACAD8
|
Health Risk |
Pathogenic |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS746960200 |
COG5
|
Health Risk |
Pathogenic |
COG5-congenital disorder of glycosylation, COG5-congenital disorder of glycosylation |
| RS746960789 |
ANO6
|
Health Risk |
Likely pathogenic |
ANO6-related disorder, ANO6-related disorder |
| RS746961162 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS746961427 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS746962599 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS746964903 |
ACTL6B
|
Health Risk |
Pathogenic |
Autism spectrum disorder, Autism spectrum disorder |
| RS746966614 |
TCOF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Treacher Collins syndrome 1, Inborn genetic diseases |
| RS746967357 |
CDK5RAP2
|
Health Risk |
Likely pathogenic |
Microcephaly 3, primary |
| RS746967490 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, Autosomal dominant nonsyndromic hearing loss 17 |
| RS746967719 |
PIGO
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS746969842 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS746970206 |
TMEM231
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 20, Meckel syndrome |
| RS746970260 |
ABHD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Triglyceride storage disease with ichthyosis, Triglyceride storage disease with ichthyosis |
| RS746970647 |
ATR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746971522 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS746971794 |
RYR1
|
Health Risk |
Likely pathogenic |
Malignant hyperthermia, susceptibility to |
| RS746971952 |
SPG11
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 11, Amyotrophic lateral sclerosis type 5 |
| RS746972142 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS746972322 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746972457 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal dominant polycystic liver disease |
| RS746972765 |
ACTA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Aortic aneurysm, familial thoracic 6 |
| RS746972930 |
CDC73
|
Health Risk |
Conflicting classifications of pathogenicity |
Parathyroid carcinoma, Hereditary cancer-predisposing syndrome |
| RS746973259 |
SETX
|
Health Risk |
Pathogenic |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS746973761 |
TMEM70
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex V (ATP synthase) deficiency, nuclear type 2 |
| RS746973873 |
CYP11B2
|
Health Risk |
Likely pathogenic |
Corticosterone 18-monooxygenase deficiency, Corticosterone methyloxidase type 2 deficiency |
| RS746975723 |
NPRL3
|
Health Risk |
Pathogenic/Likely pathogenic |
Epilepsy, familial focal |
| RS746976599 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS746977730 |
KIF11
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly with or without chorioretinopathy, lymphedema |
| RS746978083 |
DAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A9 |
| RS746978701 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS746979262 |
CYP7B1
|
Health Risk |
Pathogenic |
Spastic paraplegia, Hereditary spastic paraplegia 5A |
| RS746979388 |
ANO10
|
Health Risk |
Pathogenic |
— |
| RS746979958 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS746980493 |
GDF5
|
Health Risk |
Conflicting classifications of pathogenicity |
Grebe syndrome, Acromesomelic dysplasia 2B |
| RS746980680 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, Charcot-Marie-Tooth disease type 2 |
| RS746981200 |
CNTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Compton-North congenital myopathy, Compton-North congenital myopathy |
| RS746981338 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, FG syndrome |
| RS746982385 |
ATP6V0A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Sensorineural hearing loss disorder, Renal tubulopathies |
| RS746982506 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS746982741 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS746983128 |
FANCM
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia |
| RS74698331 |
MADD
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746985605 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome with C3 anomaly, Complement component 3 deficiency |
| RS746985755 |
SORD
|
Health Risk |
Pathogenic |
Neuronopathy, distal hereditary motor |
| RS746986151 |
CCIN
|
Health Risk |
Pathogenic |
Spermatogenic failure 91, Spermatogenic failure 91 |
| RS746986165 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHARGE syndrome |
| RS746987085 |
MYH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, proximal |
| RS746987799 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS746987839 |
CFAP52
|
Health Risk |
Likely pathogenic |
Situs inversus, Situs inversus |
| RS746988006 |
HBA2
|
Health Risk |
Pathogenic |
— |
| RS746988876 |
ALG12
|
Health Risk |
Likely pathogenic |
ALG12-congenital disorder of glycosylation, ALG12-congenital disorder of glycosylation |
| RS746989288 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Inborn genetic diseases |
| RS746990436 |
CSRP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy 12 |
| RS746990528 |
PRKCSH
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic liver disease 1, Polycystic liver disease 1 |
| RS746991079 |
DPYD
|
Health Risk |
Pathogenic/Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS746991573 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS74699271 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS746993675 |
RAD51C
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS746994234 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS746994330 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746994660 |
ASCC1
|
Health Risk |
Pathogenic |
Spinal muscular atrophy with congenital bone fractures 2, Spinal muscular atrophy with congenital bone fractures 2 |
| RS746994734 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS746997654 |
FANCA
|
Health Risk |
Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS746999375 |
SLC13A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 25 |
| RS746999951 |
RDH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary retinal dystrophy, Pigmentary retinal dystrophy |
| RS746999970 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS747000305 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS747000470 |
NKX2-1
|
Health Risk |
Pathogenic |
— |
| RS747000483 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, childhood absence |
| RS747001128 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747002272 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS747002312 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |