| RS746756510 |
NBAS
|
Health Risk |
Pathogenic |
— |
| RS746756997 |
GALNS
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Mucopolysaccharidosis |
| RS746757469 |
HARS2
|
Health Risk |
Likely pathogenic |
— |
| RS746758186 |
SLC26A3
|
Health Risk |
Pathogenic |
Congenital secretory diarrhea, chloride type |
| RS746761404 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Van Maldergem syndrome 2, Hennekam lymphangiectasia-lymphedema syndrome 2 |
| RS746762030 |
TGFBR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Familial thoracic aortic aneurysm and aortic dissection |
| RS746762111 |
COG7
|
Health Risk |
Conflicting classifications of pathogenicity |
COG7 congenital disorder of glycosylation, COG7 congenital disorder of glycosylation |
| RS746762359 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyropoikilocytosis, hereditary |
| RS746762473 |
LAMA2
|
Health Risk |
Pathogenic |
— |
| RS746763506 |
FKTN
|
Health Risk |
Pathogenic |
Walker-Warburg congenital muscular dystrophy, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS746764220 |
RUBCN
|
Health Risk |
Likely pathogenic |
Spinocerebellar ataxia type 15/16, Spinocerebellar ataxia type 15/16 |
| RS746764862 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, PRPF8-related disorder |
| RS746764976 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, See cases |
| RS746765362 |
LAMB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pierson syndrome, LAMB2-related infantile-onset nephrotic syndrome |
| RS746765465 |
THRA
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS746765533 |
NPRL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial focal |
| RS746765869 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, RYR1-related disorder |
| RS746766232 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
GM1 gangliosidosis type 2, Infantile GM1 gangliosidosis |
| RS746766318 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS746766617 |
IDUA
|
Health Risk |
Pathogenic |
Hurler syndrome, Mucopolysaccharidosis type 1 |
| RS746766677 |
COL4A3
|
Health Risk |
Likely pathogenic |
Autosomal dominant Alport syndrome, Autosomal dominant Alport syndrome |
| RS746766787 |
PMS2
|
Health Risk |
Pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS746769666 |
NPHS1
|
Health Risk |
Likely pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS746770543 |
MYBPC3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS746770617 |
MYH2
|
Health Risk |
Pathogenic |
Myopathy, proximal |
| RS746770705 |
FANCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group E, Inborn genetic diseases |
| RS746772122 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS746773616 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, POLG-related disorder |
| RS746775716 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, BBS1-related disorder |
| RS746776254 |
SGSH
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS746776892 |
HOGA1
|
Health Risk |
Pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS746777092 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS746778765 |
GFM1
|
Health Risk |
Pathogenic |
— |
| RS746779107 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746779770 |
ATP2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Brody myopathy, Inborn genetic diseases |
| RS746780708 |
ALG1
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG1-congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |
| RS746781620 |
DTNBP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome |
| RS746781699 |
GPD1
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS746782115 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 4 |
| RS746782348 |
OTOGL
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS746782404 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 1, Joubert syndrome |
| RS746782582 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS746782589 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS746784282 |
CELSR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mild to moderate NDD, Mild to moderate NDD |
| RS746785436 |
LAMA2
|
Health Risk |
Likely pathogenic |
LAMA2-related muscular dystrophy, Muscular dystrophy |
| RS746785505 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS746787047 |
CRB1
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 8, Leber congenital amaurosis 8 |
| RS746787698 |
ABCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive inherited pseudoxanthoma elasticum, Pseudoxanthoma elasticum |
| RS746787955 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746790849 |
CACNA1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Episodic ataxia type 2, CACNA1A-related disorder |
| RS746792129 |
RPGRIP1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS746792200 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Van Maldergem syndrome 2, Hennekam lymphangiectasia-lymphedema syndrome 2 |
| RS746792907 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS746794574 |
SLC19A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Biotin-responsive basal ganglia disease, Biotin-responsive basal ganglia disease |
| RS746795177 |
ERCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum, group D |
| RS746795369 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Familial hemiplegic migraine |
| RS746795974 |
CEP152
|
Health Risk |
Likely pathogenic |
— |
| RS746796894 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS746797123 |
BBS9
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 9, Bardet-Biedl syndrome |
| RS746797808 |
STX3
|
Health Risk |
Conflicting classifications of pathogenicity |
Diarrhea 12, with microvillus atrophy |
| RS746798986 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Noonan syndrome 4 |
| RS746799355 |
GAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Giant axonal neuropathy 1, Inborn genetic diseases |
| RS746800397 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746800707 |
AAR2
|
Health Risk |
Likely pathogenic |
8 conditions, 8 conditions |
| RS746801054 |
SHOX
|
Health Risk |
Pathogenic |
Leri-Weill dyschondrosteosis, Leri-Weill dyschondrosteosis |
| RS746803006 |
POMT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A2 |
| RS746806459 |
GALC
|
Health Risk |
Conflicting classifications of pathogenicity |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS746806941 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS746807446 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS746807833 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia, autosomal recessive |
| RS746808159 |
MAN2B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS746808951 |
SI
|
Health Risk |
Conflicting classifications of pathogenicity |
Sucrase-isomaltase deficiency, Sucrase-isomaltase deficiency |
| RS746809573 |
AGPAT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital generalized lipodystrophy type 1, Congenital generalized lipodystrophy type 1 |
| RS746809883 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS746809939 |
CASK
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, CASK-related |
| RS746811167 |
SYNJ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset Parkinson disease 20, Developmental and epileptic encephalopathy |
| RS746813123 |
WNT10A
|
Health Risk |
Likely pathogenic |
Tooth agenesis, selective |
| RS746813353 |
CYP17A1
|
Health Risk |
Likely pathogenic |
Deficiency of steroid 17-alpha-monooxygenase, Deficiency of steroid 17-alpha-monooxygenase |
| RS746813506 |
HPS6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 6, Hermansky-Pudlak syndrome 6 |
| RS746815510 |
POMC
|
Health Risk |
Pathogenic |
Inborn genetic diseases, POMC-related disorder |
| RS746817140 |
IL17RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 51, Immunodeficiency 51 |
| RS746817480 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS746818109 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS746818112 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746818113 |
CTH
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystathioninuria, Cystathioninuria |
| RS746820022 |
PDE6C
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS746821851 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS746822140 |
PLEKHG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS746822265 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS746822330 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease |
| RS746822837 |
NLRC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Periodic fever-infantile enterocolitis-autoinflammatory syndrome, Familial cold autoinflammatory syndrome 4 |
| RS746823238 |
POMT1
|
Health Risk |
Pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS746823852 |
RP1
|
Health Risk |
Pathogenic |
— |
| RS746824139 |
NF1
|
Health Risk |
Pathogenic |
Neurofibromatosis, type 1 |
| RS746824207 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746824252 |
XPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum group A, Xeroderma pigmentosum group A |
| RS746824716 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS746824729 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 5 |
| RS746826852 |
TRIM37
|
Health Risk |
Conflicting classifications of pathogenicity |
Mulibrey nanism syndrome, Mulibrey nanism syndrome |
| RS746827368 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyropoikilocytosis, hereditary |