| RS746563151 |
AGBL5
|
Health Risk |
Likely pathogenic |
— |
| RS746563654 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS746563980 |
ACOX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Acyl-CoA oxidase deficiency, Inborn genetic diseases |
| RS746566593 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS746566745 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS746566873 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe early-childhood-onset retinal dystrophy, Retinal dystrophy |
| RS746567958 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS746569192 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746570875 |
IGF1R
|
Health Risk |
Pathogenic |
— |
| RS746570981 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Macular degeneration, early-onset |
| RS746571094 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, Inborn genetic diseases |
| RS746571208 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS746571244 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS746572271 |
KIF26A
|
Health Risk |
Pathogenic |
Cortical dysplasia, complex |
| RS746572452 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS746572548 |
TRMT1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, autosomal recessive 68 |
| RS746574289 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS746574955 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS746574978 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746575171 |
PNPLA1
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 10, Autosomal recessive congenital ichthyosis 10 |
| RS746575438 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS746575551 |
CBS
|
Health Risk |
Likely pathogenic |
Classic homocystinuria, Classic homocystinuria |
| RS746576915 |
ERCC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group F |
| RS746578841 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Peroxisome biogenesis disorder |
| RS746578868 |
GRIN2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 46 |
| RS746579020 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS746579337 |
EGR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, type I |
| RS746579947 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746581330 |
APC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, APC-Associated Polyposis Disorders |
| RS746581409 |
TYR
|
Health Risk |
Pathogenic/Likely pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1B |
| RS746581714 |
IGHMBP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2S, Autosomal recessive distal spinal muscular atrophy 1 |
| RS746582303 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS746582620 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS746583007 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS746584417 |
PCNT
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS746585235 |
SGCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonic dystonia 11, Inborn genetic diseases |
| RS746585658 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS746586029 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS746587907 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, DNAH11-related disorder |
| RS746588726 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS746588865 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1G |
| RS746590157 |
ELP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial dysautonomia, Medulloblastoma |
| RS746591648 |
NEK1
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS746591926 |
DHCR7
|
Health Risk |
Pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS746592911 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Carcinoma of colon, Hereditary cancer-predisposing syndrome |
| RS746593718 |
TBCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive Kenny-Caffey syndrome |
| RS746594822 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Atrial septal defect 7 |
| RS746594889 |
MAK
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 62 |
| RS746594902 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746595127 |
CERKL
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS746595362 |
CHAT
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial infantile myasthenia, Familial infantile myasthenia |
| RS746597173 |
CRB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 8, Retinitis pigmentosa 12 |
| RS746597270 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Inborn genetic diseases |
| RS746597831 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Hematuria |
| RS746598421 |
ETFDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Glutaric acidemia type 2C |
| RS746598992 |
ATM
|
Health Risk |
Likely pathogenic |
Malignant tumor of breast, Malignant tumor of breast |
| RS746599076 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group J, Familial cancer of breast |
| RS746599803 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Sotos syndrome |
| RS746601093 |
MOGS
|
Health Risk |
Pathogenic |
MOGS-congenital disorder of glycosylation, MOGS-congenital disorder of glycosylation |
| RS746602135 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 2 with or without anosmia, Pfeiffer syndrome |
| RS746602151 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS746602244 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial meningioma |
| RS746602775 |
ATP13A3
|
Health Risk |
Pathogenic |
Pulmonary arterial hypertension, Pulmonary hypertension |
| RS746603120 |
REL
|
Health Risk |
Pathogenic |
— |
| RS746604591 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, STXBP2-related disorder |
| RS746604683 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS746604945 |
CFAP300
|
Health Risk |
Likely pathogenic |
— |
| RS746606852 |
ZFYVE26
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 15, Hereditary spastic paraplegia 15 |
| RS746607414 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS746607455 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS746607723 |
NEU1
|
Health Risk |
Conflicting classifications of pathogenicity |
Non-immune hydrops fetalis, Sialidosis type 2 |
| RS746607851 |
MRPL39
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Combined oxidative phosphorylation deficiency 59 |
| RS746608405 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS746608568 |
FLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS746609914 |
FOXRED1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746609932 |
GDAP1
|
Health Risk |
Likely pathogenic |
Peripheral neuropathy, Peripheral neuropathy |
| RS746609972 |
ABCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dubin-Johnson syndrome, Dubin-Johnson syndrome |
| RS746610168 |
PMM2
|
Health Risk |
Conflicting classifications of pathogenicity |
PMM2-congenital disorder of glycosylation, Inborn genetic diseases |
| RS746610206 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746610406 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1F, Usher syndrome type 1D |
| RS746610724 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS746611627 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS746612410 |
KLHL7
|
Health Risk |
Pathogenic |
PERCHING syndrome, Neurodevelopmental delay |
| RS746612786 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS746612831 |
OFD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Orofaciodigital syndrome I |
| RS746612913 |
POP1
|
Health Risk |
Pathogenic |
— |
| RS746613509 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 4, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS746613525 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS746614172 |
NUS1
|
Health Risk |
Likely pathogenic |
NUS1-related disorder, NUS1-related disorder |
| RS746614226 |
NIPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 6, Hereditary spastic paraplegia 6 |
| RS746615217 |
CNTNAP2
|
Health Risk |
Pathogenic |
Cortical dysplasia-focal epilepsy syndrome, Cortical dysplasia-focal epilepsy syndrome |
| RS746616255 |
ERCC6
|
Health Risk |
Pathogenic |
— |
| RS746617574 |
XPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum group A, Xeroderma pigmentosum |
| RS746618021 |
ADGRV1
|
Health Risk |
Pathogenic |
Usher syndrome, Usher syndrome |
| RS746621216 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Inborn genetic diseases |
| RS746621296 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746621306 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS746623019 |
C5
|
Health Risk |
Likely pathogenic |
— |
| RS746623393 |
ATM
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS746623465 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |