| RS746827841 |
HPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746828415 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746829047 |
MPDZ
|
Health Risk |
Pathogenic |
— |
| RS746829106 |
EYS
|
Health Risk |
Pathogenic |
— |
| RS746829414 |
LAMA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, Inborn genetic diseases |
| RS746829669 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Inborn genetic diseases |
| RS746830415 |
TJP2
|
Health Risk |
Pathogenic |
TJP2-related disorder, TJP2-related disorder |
| RS746831347 |
TMEM127
|
Health Risk |
Conflicting classifications of pathogenicity |
Pheochromocytoma, Hereditary pheochromocytoma and paraganglioma |
| RS746831560 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS746832628 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, CTNNA1-related disorder |
| RS746833089 |
GRM7
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with seizures, hypotonia |
| RS746833511 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial septal defect 7, Primary dilated cardiomyopathy |
| RS746834149 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial melanoma, Hereditary cancer-predisposing syndrome |
| RS746834335 |
FHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked myopathy with postural muscle atrophy, Cardiovascular phenotype |
| RS746834464 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS746835381 |
NDUFAF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Mitochondrial complex I deficiency |
| RS746835434 |
LARP7
|
Health Risk |
Pathogenic |
— |
| RS746836038 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS746836333 |
ABCA3
|
Health Risk |
Likely pathogenic |
— |
| RS746837034 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, USH2A-related disorder |
| RS746837045 |
KDM5B
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, autosomal recessive 65 |
| RS746837108 |
FARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 14, Combined oxidative phosphorylation defect type 14 |
| RS746837986 |
AXIN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Oligodontia-cancer predisposition syndrome, Colorectal cancer |
| RS746838237 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS746838793 |
EARS2
|
Health Risk |
Likely pathogenic |
— |
| RS746839544 |
COQ6
|
Health Risk |
Pathogenic |
Familial steroid-resistant nephrotic syndrome with sensorineural deafness, Familial steroid-resistant nephrotic syndrome with sensorineural deafness |
| RS746840086 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746841307 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Inborn genetic diseases |
| RS746841401 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS746842267 |
SLC6A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperekplexia 3, Inborn genetic diseases |
| RS746842727 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 36 |
| RS746842822 |
CYP11B2
|
Health Risk |
Likely pathogenic |
Corticosterone methyloxidase type 2 deficiency, Corticosterone 18-monooxygenase deficiency |
| RS746844529 |
HPS5
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome 5, Hermansky-Pudlak syndrome 5 |
| RS746844753 |
LAMA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS746846045 |
DMP1
|
Health Risk |
Likely pathogenic |
— |
| RS746846673 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS746847103 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS746847960 |
PHEX
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial X-linked hypophosphatemic vitamin D refractory rickets, Familial X-linked hypophosphatemic vitamin D refractory rickets |
| RS746848153 |
CACNA1A
|
Health Risk |
Likely pathogenic |
— |
| RS746848165 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS746848315 |
CHST3
|
Health Risk |
Pathogenic/Likely pathogenic |
Spondyloepiphyseal dysplasia with congenital joint dislocations, Spondyloepiphyseal dysplasia with congenital joint dislocations |
| RS746849558 |
POMT1
|
Health Risk |
Pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1 |
| RS746849639 |
DNAAF5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS746849675 |
NPHP3
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis 3 |
| RS746849797 |
ODAD3
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia 30, Primary ciliary dyskinesia 30 |
| RS746850084 |
MRE11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia-like disorder |
| RS746850653 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS746850663 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, APC-related disorder |
| RS746850858 |
MYPN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1KK, Dilated cardiomyopathy 1KK |
| RS746850899 |
KCNJ11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS746852311 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS746853821 |
AR
|
Health Risk |
Conflicting classifications of pathogenicity |
Androgen resistance syndrome, AR-related disorder |
| RS746853951 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial neonatal |
| RS746854470 |
HADH
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of 3-hydroxyacyl-CoA dehydrogenase, Hyperinsulinemic hypoglycemia |
| RS746854614 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS746854983 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Haddad syndrome, Hereditary cancer-predisposing syndrome |
| RS746855352 |
GOSR2
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive myoclonic epilepsy, Muscular dystrophy |
| RS746855701 |
ASS1
|
Health Risk |
Pathogenic |
Citrullinemia, Citrullinemia |
| RS746856770 |
AIFM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth Neuropathy X, Combined oxidative phosphorylation deficiency |
| RS746857727 |
BLM
|
Health Risk |
Pathogenic/Likely pathogenic |
Bloom syndrome, Bloom syndrome |
| RS746859902 |
ADAT3
|
Health Risk |
Pathogenic |
Intellectual disability-strabismus syndrome, Intellectual disability-strabismus syndrome |
| RS746860249 |
TBCK
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypotonia, infantile |
| RS746860401 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS746861070 |
PIGB
|
Health Risk |
Pathogenic |
— |
| RS746861398 |
CEP78
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746862066 |
GALNS
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-IV-A |
| RS746862161 |
SLC13A3
|
Health Risk |
Likely pathogenic |
Leukoencephalopathy, acute reversible |
| RS746862304 |
ARSA
|
Health Risk |
Conflicting classifications of pathogenicity |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS746863482 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS746863848 |
ASPM
|
Health Risk |
Likely pathogenic |
Microcephaly 5, primary |
| RS746864661 |
OBSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
3M syndrome 2, 3M syndrome 2 |
| RS746865307 |
PCDH15
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 1F, Autosomal recessive nonsyndromic hearing loss 23 |
| RS746867546 |
MYO18B
|
Health Risk |
Pathogenic |
— |
| RS746867724 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Rod-cone dystrophy |
| RS746868162 |
MAN2B1
|
Health Risk |
Pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS746869680 |
LAMC3
|
Health Risk |
Pathogenic |
— |
| RS746870368 |
RAD51C
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS746870927 |
KL
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS746870942 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Hereditary cancer-predisposing syndrome |
| RS746871581 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS746871920 |
USH1C
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 18A, Autosomal recessive nonsyndromic hearing loss 18A |
| RS746872839 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS746873023 |
CCDC8
|
Health Risk |
Likely pathogenic |
3M syndrome 3, 3M syndrome 3 |
| RS746873768 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS746873807 |
TEAD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS746874042 |
SKIC3
|
Health Risk |
Likely pathogenic |
Trichohepatoenteric syndrome 1, Trichohepatoenteric syndrome 1 |
| RS746874909 |
MCM10
|
Health Risk |
Pathogenic |
Immunodeficiency 80 with or without congenital cardiomyopathy, Immunodeficiency 80 with or without congenital cardiomyopathy |
| RS746875019 |
OFD1
|
Health Risk |
Pathogenic |
— |
| RS746875134 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 1, Bardet-Biedl syndrome |
| RS746875668 |
PHKA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXa1, Inborn genetic diseases |
| RS746876753 |
NAGLU
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2V, Mucopolysaccharidosis |
| RS746877365 |
DSP
|
Health Risk |
Pathogenic/Likely pathogenic |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS746877433 |
ACSF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS746877994 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS746878731 |
UNG
|
Health Risk |
Likely pathogenic |
Hyper-IgM syndrome type 5, Hyper-IgM syndrome type 5 |
| RS746878988 |
EPG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Vici syndrome, Inborn genetic diseases |
| RS746879032 |
SAMD7
|
Health Risk |
Pathogenic |
Macular dystrophy with or without cone dysfunction, Macular dystrophy with or without cone dysfunction |
| RS746879923 |
CNNM4
|
Health Risk |
Pathogenic |
Jalili syndrome, Retinal dystrophy |
| RS746881295 |
MRPS22
|
Health Risk |
Pathogenic |
— |
| RS746882046 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Familial thoracic aortic aneurysm and aortic dissection |