| RS747130165 |
CEP164
|
Health Risk |
Pathogenic |
Nephronophthisis 15, Nephronophthisis 15 |
| RS747130246 |
LRSAM1
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2P, Charcot-Marie-Tooth disease |
| RS747130957 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Dilated cardiomyopathy 1G |
| RS747131454 |
JAK3
|
Health Risk |
Pathogenic/Likely pathogenic |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, T-B+ severe combined immunodeficiency due to JAK3 deficiency |
| RS747133313 |
COL9A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epiphyseal dysplasia, multiple |
| RS747134711 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS747135310 |
TCTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Meckel syndrome |
| RS747136051 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS747136174 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
AHDC1-related intellectual disability - obstructive sleep apnea - mild dysmorphism syndrome, Inborn genetic diseases |
| RS747136342 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS747136651 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS747136766 |
CACNA1D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Hearing impairment |
| RS747138265 |
FOXG1
|
Health Risk |
Conflicting classifications of pathogenicity |
FOXG1 disorder, Inborn genetic diseases |
| RS747138345 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS747138507 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, Hajdu-Cheney syndrome |
| RS747138950 |
NANS;TRIM14
|
Health Risk |
Pathogenic |
— |
| RS747139265 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS747139295 |
CFTR
|
Health Risk |
Pathogenic |
Obstructive azoospermia, Obstructive azoospermia |
| RS747139582 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS747140161 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS747140718 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS747142039 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Tetralogy of Fallot |
| RS747142680 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Inborn genetic diseases |
| RS747143343 |
SMPD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Niemann-Pick disease, type A |
| RS747143752 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS747144008 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Inborn genetic diseases |
| RS747146523 |
ANO5
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2L, Gnathodiaphyseal dysplasia |
| RS747148023 |
PALB2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS747148416 |
FOXE3
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital primary aphakia, Anterior segment dysgenesis |
| RS747148568 |
PLXNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747149179 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS747149353 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS747150559 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 9, Complement component 3 deficiency |
| RS747150601 |
COQ8A
|
Health Risk |
Pathogenic |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS747150965 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS747153406 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS747153940 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS747154237 |
NAGS
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperammonemia, type III |
| RS747154432 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
POLG-related disorder, Progressive sclerosing poliodystrophy |
| RS747155575 |
GBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adult polyglucosan body disease, Glycogen storage disease |
| RS747155741 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 2, Autosomal dominant nonsyndromic hearing loss 11 |
| RS747155746 |
NAGLU
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-B |
| RS747157774 |
AIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, AIP-related disorder |
| RS747159785 |
EXPH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Epidermolysis bullosa simplex 4, localized or generalized intermediate |
| RS747159816 |
BBS12
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 12 |
| RS747160538 |
ADAMTSL4
|
Health Risk |
Pathogenic/Likely pathogenic |
Ectopia lentis et pupillae, Ectopia lentis 2 |
| RS747160833 |
TRIOBP
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 28, Autosomal recessive nonsyndromic hearing loss 28 |
| RS747160949 |
USH2A
|
Health Risk |
Pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS747161108 |
ADAMTSL4
|
Health Risk |
Pathogenic |
— |
| RS747161372 |
ASRGL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747161431 |
LTBP2
|
Health Risk |
Pathogenic |
— |
| RS747161494 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS747161831 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS747162821 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS747162992 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS747164054 |
TNFRSF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
TNF receptor-associated periodic fever syndrome (TRAPS), Autoinflammatory syndrome |
| RS747165215 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747165335 |
WDR19
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Senior-Loken syndrome 8 |
| RS747165711 |
SLC5A6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747165958 |
DZIP1L
|
Health Risk |
Likely pathogenic |
Polycystic kidney disease 5, DZIP1L-related disorder |
| RS747166010 |
TTC19
|
Health Risk |
Pathogenic |
Mitochondrial complex III deficiency nuclear type 2, Inborn genetic diseases |
| RS747166529 |
TRIO
|
Health Risk |
Pathogenic |
Micrognathia-recurrent infections-behavioral abnormalities-mild intellectual disability syndrome, Micrognathia-recurrent infections-behavioral abnormalities-mild intellectual disability syndrome |
| RS747167000 |
ALPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypophosphatasia, ALPL-related disorder |
| RS747167770 |
COL4A4
|
Health Risk |
Likely pathogenic |
Autosomal recessive Alport syndrome, COL4A4-related disorder |
| RS747168398 |
SPTLC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS747169620 |
STAR
|
Health Risk |
Pathogenic |
Congenital lipoid adrenal hyperplasia due to STAR deficency, Syndactyly-telecanthus-anogenital and renal malformations syndrome |
| RS747169857 |
UNC13D
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS747170980 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS747171013 |
CHST3
|
Health Risk |
Pathogenic |
Spondyloepiphyseal dysplasia with congenital joint dislocations, Spondyloepiphyseal dysplasia with congenital joint dislocations |
| RS74717111 |
OPA3
|
Health Risk |
Conflicting classifications of pathogenicity |
3-Methylglutaconic aciduria type 3, Optic atrophy 3 |
| RS747171418 |
DCLRE1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to DCLRE1C deficiency, Histiocytic medullary reticulosis |
| RS747171653 |
CEP164
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 15, Nephronophthisis 15 |
| RS747172511 |
GRIN2B
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal dominant 6 |
| RS747172803 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS747175358 |
BSCL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Monogenic diabetes, Charcot-Marie-Tooth disease type 2 |
| RS747175448 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS747176117 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Febrile seizures |
| RS747177622 |
AFG2B
|
Health Risk |
Pathogenic |
Hearing loss, autosomal recessive 119 |
| RS747178896 |
MAPT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747179265 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, NEB-related disorder |
| RS747179298 |
TPP1
|
Health Risk |
Pathogenic |
— |
| RS747180228 |
UNC13D
|
Health Risk |
Pathogenic/Likely pathogenic |
Autoinflammatory syndrome, Familial hemophagocytic lymphohistiocytosis 3 |
| RS747180813 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS747181293 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS747181703 |
TMEM126B
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 29 |
| RS747182299 |
DNMT3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Centromeric instability of chromosomes 1, 9 and 16 and immunodeficiency |
| RS747182653 |
MTHFR
|
Health Risk |
Conflicting classifications of pathogenicity |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, Homocystinuria due to methylene tetrahydrofolate reductase deficiency |
| RS747183300 |
C2CD3
|
Health Risk |
Pathogenic |
— |
| RS747183517 |
GNB1
|
Health Risk |
Likely pathogenic |
— |
| RS747184077 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, FANCA-related disorder |
| RS747184649 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS747185260 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS747187696 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jervell and Lange-Nielsen syndrome 1, Atrial fibrillation |
| RS747189218 |
BACH2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747189975 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS747190078 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, Alagille syndrome due to a NOTCH2 point mutation |
| RS747190555 |
DNAH9
|
Health Risk |
Pathogenic |
Ciliary dyskinesia, primary |
| RS747192384 |
ACOX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Acyl-CoA oxidase deficiency, Acyl-CoA oxidase deficiency |
| RS747192873 |
GUCY2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747193364 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |