| RS747506380 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability) |
| RS747506979 |
GBA1
|
Health Risk |
Pathogenic |
Gaucher disease type I, Gaucher disease |
| RS747507457 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS747508159 |
LIPA
|
Health Risk |
Pathogenic |
Cholesteryl ester storage disease, Wolman disease |
| RS747508165 |
G6PC3
|
Health Risk |
Pathogenic |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
| RS747509922 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS747510615 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS747510783 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS747511049 |
TCIRG1
|
Health Risk |
Pathogenic |
Autosomal recessive osteopetrosis 1, Autosomal recessive osteopetrosis 1 |
| RS747512450 |
PROM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 1, Retinitis pigmentosa 41 |
| RS747512816 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS747513238 |
PYGM
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type V |
| RS747513278 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS747513823 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS747514385 |
CYP7B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 5A, Hereditary spastic paraplegia |
| RS747514399 |
CYP7B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Spastic paraplegia, Hereditary spastic paraplegia 5A |
| RS747514855 |
CBY1
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome |
| RS747515104 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Nephronophthisis |
| RS747515115 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, autosomal dominant |
| RS747516133 |
PCDH15
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 23, Usher syndrome type 1D |
| RS747516555 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1, Autosomal dominant nonsyndromic hearing loss 11 |
| RS747516623 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS747517546 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS747518441 |
SDHB
|
Health Risk |
Likely pathogenic |
Pheochromocytoma, Pheochromocytoma/paraganglioma syndrome 4 |
| RS747518922 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747520197 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS747522183 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS747522386 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS747522483 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS747522516 |
EIF2B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS747523570 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Myofibrillar myopathy 4 |
| RS747524697 |
CEBPE
|
Health Risk |
Likely pathogenic |
Specific granule deficiency 1, SPECIFIC GRANULE DEFICIENCY 1 |
| RS747526439 |
SCN8A
|
Health Risk |
Likely pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS747526674 |
COL18A1
|
Health Risk |
Pathogenic |
— |
| RS747527621 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS747527726 |
MMACHC
|
Health Risk |
Pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS747527740 |
PRDM9
|
Health Risk |
Pathogenic |
Genetic non-acquired premature ovarian failure, Genetic non-acquired premature ovarian failure |
| RS747529236 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS747529491 |
SCN5A
|
Health Risk |
Pathogenic |
— |
| RS747529694 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS747530550 |
SLC10A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747531341 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS747531733 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, FAT4-related disorder |
| RS747531940 |
SGCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonic dystonia 11, Myoclonic dystonia 11 |
| RS747532570 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS747533547 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS747534491 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS747534508 |
ITGB3
|
Health Risk |
Pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS747534563 |
TULP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747534810 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 4, Fibromatosis |
| RS747536139 |
SLC35A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autism spectrum disorder - epilepsy - arthrogryposis syndrome, Autism spectrum disorder - epilepsy - arthrogryposis syndrome |
| RS747536638 |
PDZD7
|
Health Risk |
Likely pathogenic |
Hearing loss, autosomal recessive 57 |
| RS747536867 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS747536886 |
FBXL4
|
Health Risk |
Pathogenic |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS747538224 |
TBC1D24
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, developmental delay with seizures |
| RS747538432 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, Inborn genetic diseases |
| RS747538587 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS747539101 |
UPB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of beta-ureidopropionase, Hepatocellular carcinoma |
| RS747539519 |
OTOF
|
Health Risk |
Pathogenic |
— |
| RS747539984 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS747540967 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS747541782 |
ADGRV1
|
Health Risk |
Likely pathogenic |
— |
| RS747542544 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Familial hemiplegic migraine |
| RS747544155 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 71, Short-rib thoracic dysplasia 10 with or without polydactyly |
| RS747546314 |
MYOT
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 3, Myofibrillar myopathy 3 |
| RS747546549 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome |
| RS747546798 |
FAH
|
Health Risk |
Pathogenic/Likely pathogenic |
Tyrosinemia type I, Tyrosinemia type I |
| RS747547178 |
FUS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Tremor |
| RS747547191 |
LAMA3
|
Health Risk |
Likely pathogenic |
Junctional epidermolysis bullosa gravis of Herlitz, Junctional epidermolysis bullosa gravis of Herlitz |
| RS747548016 |
BTD
|
Health Risk |
Pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS747548086 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS74754826 |
MBL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mannose-binding lectin deficiency, Mannose-binding lectin deficiency |
| RS747549006 |
TSEN54
|
Health Risk |
Pathogenic |
— |
| RS747549182 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Porencephaly 2, Porencephaly 2 |
| RS747549978 |
PKLR
|
Health Risk |
Likely pathogenic |
Pyruvate kinase deficiency of red cells, Pyruvate kinase deficiency of red cells |
| RS747550431 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS747550558 |
DNAH8
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS747550590 |
MMACHC
|
Health Risk |
Pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS747551593 |
MYO15A
|
Health Risk |
Pathogenic |
— |
| RS747552453 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Transitory neonatal diabetes mellitus |
| RS747553429 |
TRPM1
|
Health Risk |
Likely pathogenic |
Congenital stationary night blindness 1C, Congenital stationary night blindness 1C |
| RS74755361 |
DSG4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypotrichosis 6, Hypotrichosis 6 |
| RS747554139 |
CDKL5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 2 |
| RS747554856 |
SLC6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy with myoclonic atonic seizures, Epilepsy with myoclonic atonic seizures |
| RS747555346 |
BBS7
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 7 |
| RS747555402 |
KDM6B
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities, Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities |
| RS747555833 |
ABCG8
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS747556765 |
STXBP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS747557184 |
TUBGCP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747557404 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS747557411 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS747557639 |
DCX
|
Health Risk |
Pathogenic |
— |
| RS747558822 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747559032 |
ACTN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Thrombocytopenia, Macrothrombocytopenia |
| RS747559034 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS747559986 |
LARS2;LARS2-AS1
|
Health Risk |
Likely pathogenic |
— |
| RS747560095 |
TH
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive DOPA responsive dystonia, Autosomal recessive DOPA responsive dystonia |
| RS747561252 |
AIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747561441 |
FREM2
|
Health Risk |
Pathogenic |
— |
| RS747563189 |
ZMPSTE24
|
Health Risk |
Conflicting classifications of pathogenicity |
Mandibuloacral dysplasia with type B lipodystrophy, ZMPSTE24-related disorder |