| RS747685252 |
TRIM32
|
Health Risk |
Pathogenic/Likely pathogenic |
Limb-girdle muscular dystrophy, Bardet-Biedl syndrome |
| RS747685515 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747686377 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS747687191 |
EIF2AK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolcott-Rallison dysplasia, Wolcott-Rallison dysplasia |
| RS747688660 |
PKD2
|
Health Risk |
Pathogenic |
Autosomal dominant polycystic kidney disease, Autosomal dominant polycystic kidney disease |
| RS747689685 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS747689845 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747691921 |
POMGNT2
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a |
| RS747692385 |
PIGK
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with hypotonia and cerebellar atrophy, with or without seizures |
| RS747692546 |
FANCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group E, Fanconi anemia complementation group E |
| RS747694453 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS747694886 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Classic Hodgkin lymphoma, Classic Hodgkin lymphoma |
| RS747695245 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS747695999 |
KCNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Uterine carcinosarcoma, Uterine carcinosarcoma |
| RS747696546 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Dextro-looped transposition of the great arteries, Inborn genetic diseases |
| RS747699128 |
NPHP4
|
Health Risk |
Likely pathogenic |
Senior-Loken syndrome 4, Nephronophthisis 4 |
| RS747700106 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS747700126 |
PEPD
|
Health Risk |
Pathogenic/Likely pathogenic |
Prolidase deficiency, Prolidase deficiency |
| RS747700209 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747701761 |
ANK1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spherocytosis type 1, Hereditary spherocytosis type 1 |
| RS747701845 |
P3H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis Imperfecta, Recessive |
| RS747702749 |
F11
|
Health Risk |
Pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS747703354 |
ABCB4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747704211 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS747704276 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Atrial fibrillation |
| RS747704697 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal Kniest-like syndrome, Schwartz-Jampel syndrome |
| RS747706524 |
CIC
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal dominant 45 |
| RS747708863 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS747709330 |
APC2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747709527 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
GM1 gangliosidosis, Mucopolysaccharidosis |
| RS747710152 |
TCTN3
|
Health Risk |
Pathogenic |
Orofacial-digital syndrome IV, Joubert syndrome 18 |
| RS747710308 |
LAMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia - intellectual disability - oculomotor apraxia - cerebellar cysts syndrome, Ataxia - intellectual disability - oculomotor apraxia - cerebellar cysts syndrome |
| RS747710478 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS747710683 |
SCN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial infantile |
| RS747711259 |
NTRK1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Charcot-Marie-Tooth disease |
| RS747711431 |
KIAA0586
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 14 with polydactyly, Joubert syndrome 23 |
| RS747711488 |
CSTA
|
Health Risk |
Pathogenic |
Peeling skin syndrome 4, Peeling skin syndrome 4 |
| RS747712363 |
ASXL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome, Severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome |
| RS747712653 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS747713309 |
CR2
|
Health Risk |
Pathogenic/Likely pathogenic |
Immunodeficiency, common variable |
| RS747713348 |
TECTA
|
Health Risk |
Conflicting classifications of pathogenicity |
TECTA-related disorder, TECTA-related disorder |
| RS747713899 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Haddad syndrome, Hereditary cancer-predisposing syndrome |
| RS747713929 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS747714077 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS747714452 |
ACAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of acetyl-CoA acetyltransferase, Inborn genetic diseases |
| RS747714932 |
FHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked myopathy with postural muscle atrophy, X-linked myopathy with postural muscle atrophy |
| RS747715399 |
GALE
|
Health Risk |
Likely pathogenic |
UDPglucose-4-epimerase deficiency, Thrombocytopenia 13 |
| RS747715551 |
HK1
|
Health Risk |
Pathogenic |
— |
| RS747717847 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, CHARGE syndrome |
| RS747718173 |
VPS13D
|
Health Risk |
Pathogenic |
— |
| RS747718728 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS747719105 |
ATL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS747719953 |
ANO5
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2L, Gnathodiaphyseal dysplasia |
| RS747721259 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, APC-Associated Polyposis Disorders |
| RS747721968 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS747722195 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS747722455 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS747723062 |
GPNMB
|
Health Risk |
Pathogenic |
Amyloidosis, primary localized cutaneous |
| RS747723074 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS747723242 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2O, Congenital Muscular Dystrophy |
| RS747724352 |
HSD17B3
|
Health Risk |
Pathogenic |
Pseudohermaphroditism, Pseudohermaphroditism |
| RS747725187 |
ARSA
|
Health Risk |
Likely pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS747726149 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747727055 |
ATM
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS747727493 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome |
| RS747727600 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS747727601 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS74772771 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 4, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS747728381 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS747728399 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Hereditary cancer-predisposing syndrome |
| RS747728554 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747729019 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS747729228 |
TBCD
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Gastric cancer |
| RS747731841 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS747732620 |
NRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS747732980 |
SEPSECS
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontocerebellar hypoplasia type 2D, Pontocerebellar hypoplasia type 2D |
| RS747734015 |
DIS3L2
|
Health Risk |
Pathogenic |
Perlman syndrome, Perlman syndrome |
| RS747734639 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS747737281 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 2 with or without anosmia, Pfeiffer syndrome |
| RS747737475 |
NARS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental disorder with microcephaly, impaired language |
| RS747737869 |
FRRS1L
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 37 |
| RS747738988 |
EPCAM
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital diarrhea 5 with tufting enteropathy, Congenital diarrhea 5 with tufting enteropathy |
| RS747739571 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747739911 |
DIS3L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Perlman syndrome, DIS3L2-related disorder |
| RS747740477 |
MKS1
|
Health Risk |
Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS747740545 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypocalciuric hypercalcemia, Autosomal dominant hypocalcemia 1 |
| RS747742961 |
MAP2K2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS747743815 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, Hajdu-Cheney syndrome |
| RS747744094 |
DGUOK
|
Health Risk |
Pathogenic |
— |
| RS747745016 |
RASA1
|
Health Risk |
Pathogenic |
Capillary malformation-arteriovenous malformation syndrome, RASA1-related disorder |
| RS747745685 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease 4, Polycystic kidney disease 4 |
| RS747746632 |
GCDH
|
Health Risk |
Likely pathogenic |
Glutaric aciduria, type 1 |
| RS747747269 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Cardiovascular phenotype |
| RS747748537 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS747748647 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS74774946 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS747749610 |
VIPAS39
|
Health Risk |
Pathogenic/Likely pathogenic |
Arthrogryposis, renal dysfunction |
| RS747750958 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS747751038 |
RAD50
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747751954 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 3, Pyropoikilocytosis |