| RS747618737 |
LARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747619612 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS747619825 |
ACP5
|
Health Risk |
Pathogenic |
Spondyloenchondrodysplasia with immune dysregulation, Spondyloenchondrodysplasia with immune dysregulation |
| RS747619979 |
TRIOBP
|
Health Risk |
Likely pathogenic |
— |
| RS747620444 |
CCDC40
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS747620551 |
PIDD1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, autosomal recessive 75 |
| RS747621078 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy due to partial LAMA2 deficiency, LAMA2-related muscular dystrophy |
| RS747621401 |
ITGB3
|
Health Risk |
Pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS747621748 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS747622521 |
FANCF
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group F, Fanconi anemia |
| RS747622607 |
ADGRV1
|
Health Risk |
Pathogenic |
Usher syndrome type 2C, Febrile seizures |
| RS747623981 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS747624770 |
ASNS
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome, Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome |
| RS747626591 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital central hypoventilation, Neuroblastoma |
| RS747627650 |
GYG1
|
Health Risk |
Pathogenic |
Polyglucosan body myopathy type 2, Glycogen storage disease XV |
| RS747627800 |
ERMARD
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747628342 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747630187 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS747632184 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS747632686 |
TMEM260
|
Health Risk |
Pathogenic |
Structural heart defects and renal anomalies syndrome, Structural heart defects and renal anomalies syndrome |
| RS747632869 |
POLG
|
Health Risk |
Likely pathogenic |
6 conditions, Progressive sclerosing poliodystrophy |
| RS747633377 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747634832 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS747636658 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS747636808 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS747636919 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS747637190 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Inborn genetic diseases |
| RS747638599 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS747638667 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal macular dystrophy type 2, Retinitis pigmentosa |
| RS747638822 |
PEPD
|
Health Risk |
Pathogenic |
— |
| RS747642083 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS747642850 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS747643987 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS747644007 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS747644844 |
VPS13B
|
Health Risk |
Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS747645067 |
TMC1
|
Health Risk |
Pathogenic |
Delayed speech and language development, Moderate intellectual disability |
| RS747645756 |
TMC1
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 7, Nonsyndromic genetic hearing loss |
| RS747645948 |
FANCA
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS747646127 |
PRF1
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Familial hemophagocytic lymphohistiocytosis 2 |
| RS747646395 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Blepharophimosis - intellectual disability syndrome |
| RS747646413 |
GRIA3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747647882 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS747647995 |
GYG1
|
Health Risk |
Likely pathogenic |
Glycogen storage disease XV, Polyglucosan body myopathy type 2 |
| RS747648596 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Cardiovascular phenotype |
| RS747648795 |
COLQ
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 5, Congenital myasthenic syndrome 5 |
| RS747649874 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS747651345 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS747651923 |
ERCC6
|
Health Risk |
Pathogenic |
— |
| RS747652397 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa 39 |
| RS747652653 |
LRBA
|
Health Risk |
Likely pathogenic |
Combined immunodeficiency due to LRBA deficiency, Combined immunodeficiency due to LRBA deficiency |
| RS747653130 |
ADAMTS2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS747653593 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS747653875 |
NMNAT1
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis, Leber congenital amaurosis |
| RS747654057 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747655835 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS747656257 |
GAMT
|
Health Risk |
Likely pathogenic |
Deficiency of guanidinoacetate methyltransferase, Cerebral creatine deficiency syndrome |
| RS747656448 |
MYO7A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 2, Usher syndrome |
| RS747656642 |
CALR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 19, Hypertrophic cardiomyopathy 19 |
| RS747656720 |
DHCR7
|
Health Risk |
Likely pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS747656987 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS747657121 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, FBXL4-related disorder |
| RS747658523 |
WFS1
|
Health Risk |
Pathogenic |
Autosomal dominant nonsyndromic hearing loss 6, Type 2 diabetes mellitus |
| RS747658761 |
CWC27
|
Health Risk |
Likely pathogenic |
— |
| RS747658866 |
PGAP2
|
Health Risk |
Likely pathogenic |
Hyperphosphatasia with intellectual disability syndrome 3, Hyperphosphatasia with intellectual disability syndrome 3 |
| RS747659448 |
PDGFRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Infantile myofibromatosis |
| RS747659617 |
LRSAM1
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2P, Charcot-Marie-Tooth disease axonal type 2P |
| RS747660501 |
FANCG
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS747661700 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KBG syndrome |
| RS747661902 |
PIGQ
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Epilepsy |
| RS747662439 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS747662793 |
GCK
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 2, Maturity-onset diabetes of the young |
| RS747665716 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS747667004 |
ABCA5
|
Health Risk |
Likely pathogenic |
Gingival fibromatosis-hypertrichosis syndrome, Gingival fibromatosis-hypertrichosis syndrome |
| RS747667789 |
WDR35
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Short-rib thoracic dysplasia 7 with or without polydactyly |
| RS747668147 |
MMP21
|
Health Risk |
Pathogenic |
Heterotaxy, visceral |
| RS747668376 |
MTHFR
|
Health Risk |
Pathogenic |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, Homocystinuria due to methylene tetrahydrofolate reductase deficiency |
| RS747669327 |
DGKD
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747670551 |
VIPAS39
|
Health Risk |
Likely pathogenic |
Arthrogryposis, renal dysfunction |
| RS747672157 |
DDX41
|
Health Risk |
Pathogenic/Likely pathogenic |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS747672984 |
SRD5A2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency, 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency |
| RS74767530 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS747675386 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS747675437 |
USH1C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747675518 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Blepharophimosis - intellectual disability syndrome |
| RS747675676 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS747676224 |
KCTD7
|
Health Risk |
Likely pathogenic |
Progressive myoclonic epilepsy type 3, Progressive myoclonic epilepsy type 3 |
| RS747676277 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Charlevoix-Saguenay spastic ataxia |
| RS747678376 |
CREB3L1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type 16, Osteogenesis imperfecta type 16 |
| RS747680111 |
NIN
|
Health Risk |
Pathogenic |
Seckel syndrome 7, Seckel syndrome 7 |
| RS747680932 |
TSHR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hyperthyroidism due to mutations in TSH receptor, Hypothyroidism due to TSH receptor mutations |
| RS747681588 |
ADCY10
|
Health Risk |
Pathogenic |
— |
| RS747681609 |
MC4R
|
Health Risk |
Pathogenic/Likely pathogenic |
Obesity, BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 20 |
| RS747682416 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS747682469 |
GPR179
|
Health Risk |
Pathogenic |
— |
| RS747682836 |
USP26
|
Health Risk |
Pathogenic |
Spermatogenic failure, X-linked |
| RS747683527 |
MCOLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucolipidosis type IV, Mucolipidosis type IV |
| RS747683665 |
POLR3A
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukodystrophy, hypomyelinating |
| RS747683934 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 7, Singleton-Merten syndrome 1 |
| RS747684069 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Sarcoglycanopathy, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS747684283 |
PDE6B
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 40, Retinal dystrophy |