| RS763711252 |
DYNC1H1
|
Health Risk |
Likely pathogenic |
— |
| RS763711863 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Myopathy |
| RS763712423 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS763712887 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS763712971 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS763713221 |
MCCC1
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylcrotonyl-CoA carboxylase 1 deficiency, 3-methylcrotonyl-CoA carboxylase 1 deficiency |
| RS763713707 |
SLC38A8
|
Health Risk |
Pathogenic |
— |
| RS763715229 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, Generalized epilepsy with febrile seizures plus |
| RS763715733 |
CPAP
|
Health Risk |
Likely pathogenic |
Microcephaly 6, primary |
| RS763715899 |
TYR
|
Health Risk |
Pathogenic/Likely pathogenic |
Oculocutaneous albinism type 1A, SKIN/HAIR/EYE PIGMENTATION 3 |
| RS763715993 |
FGA
|
Health Risk |
Pathogenic |
Familial dysfibrinogenemia, Congenital afibrinogenemia |
| RS763716590 |
SPTB
|
Health Risk |
Pathogenic |
Hereditary spherocytosis type 2, Hereditary spherocytosis type 2 |
| RS763716638 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS763716866 |
DNMT3A
|
Health Risk |
Likely pathogenic |
— |
| RS763717355 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS763717800 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS763718380 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS763718499 |
EXPH5
|
Health Risk |
Pathogenic |
— |
| RS763718617 |
TRMU
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS763718818 |
EXT2
|
Health Risk |
Pathogenic |
Exostoses, multiple |
| RS763719276 |
EPM2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Inborn genetic diseases |
| RS763719290 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Inborn genetic diseases |
| RS763719304 |
ELP1
|
Health Risk |
Likely pathogenic |
Familial dysautonomia, Familial dysautonomia |
| RS763719430 |
LMF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS763719688 |
BBS7
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 7 |
| RS763721044 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Hearing loss |
| RS763721360 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS763721411 |
ABCA3
|
Health Risk |
Pathogenic |
— |
| RS763721668 |
USP7
|
Health Risk |
Likely pathogenic |
USP7-related disorder, USP7-related disorder |
| RS763722868 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763722972 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS763724025 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS763724281 |
SAMD9L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763727038 |
ALG3
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG3-congenital disorder of glycosylation, ALG3-congenital disorder of glycosylation |
| RS763729258 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS763729448 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial septal defect 7, Cardiovascular phenotype |
| RS763729848 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS763729954 |
RELA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucocutaneous ulceration, chronic |
| RS763730249 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS763730264 |
AP4B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Hereditary spastic paraplegia 47 |
| RS763733110 |
ADGRV1
|
Health Risk |
Likely pathogenic |
Usher syndrome, Usher syndrome |
| RS763733217 |
CANT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Epiphyseal dysplasia, multiple |
| RS763733251 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS763733996 |
FANCD2
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS763734157 |
F5
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital factor V deficiency, Inborn genetic diseases |
| RS763734477 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinase-positive oculocutaneous albinism, SKIN/HAIR/EYE PIGMENTATION 1 |
| RS763735590 |
CC2D2A
|
Health Risk |
Pathogenic |
Joubert syndrome 9, Meckel-Gruber syndrome |
| RS763737123 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS763737197 |
THBD
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome with thrombomodulin anomaly, Thrombomodulin-related bleeding disorder |
| RS763737257 |
ANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 1, Spherocytosis |
| RS763737398 |
IFT140
|
Health Risk |
Pathogenic/Likely pathogenic |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS763737752 |
AFG2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome, Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome |
| RS763737931 |
EPRS1
|
Health Risk |
Pathogenic |
Leukodystrophy, hypomyelinating |
| RS763738559 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS763738657 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 1, Bardet-Biedl syndrome |
| RS763739193 |
SLC7A7
|
Health Risk |
Pathogenic |
Lysinuric protein intolerance, Lysinuric protein intolerance |
| RS763740152 |
CDHR1
|
Health Risk |
Likely pathogenic |
— |
| RS763740623 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS763742755 |
TCF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins syndrome, Pitt-Hopkins syndrome |
| RS763742779 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS763743788 |
DNHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS763743962 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS763744498 |
ABCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763745734 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS763745871 |
GPX4
|
Health Risk |
Likely pathogenic |
Spondylometaphyseal dysplasia, Sedaghatian type |
| RS763745936 |
PTPN23
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763746485 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Li-Fraumeni syndrome, Li-Fraumeni syndrome 1 |
| RS763746566 |
PCNT
|
Health Risk |
Pathogenic |
— |
| RS763747258 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS763749576 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Cardiomyopathy |
| RS763749755 |
PCARE
|
Health Risk |
Pathogenic |
— |
| RS763750448 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Intellectual disability |
| RS763751899 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS763752752 |
KIAA0753
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763752868 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS763754846 |
STAT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyper-IgE recurrent infection syndrome 1, autosomal dominant |
| RS763755514 |
CR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS763755540 |
IFT122
|
Health Risk |
Pathogenic |
Cranioectodermal dysplasia 1, Cranioectodermal dysplasia 1 |
| RS763757845 |
FAM222A
|
Health Risk |
Likely pathogenic |
Abnormal brain morphology, Abnormal brain morphology |
| RS763758904 |
NTRK1
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease, Hereditary insensitivity to pain with anhidrosis |
| RS763759308 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS763759470 |
RP1L1
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS763759889 |
STAT1
|
Health Risk |
Pathogenic |
Immunodeficiency 31B, Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome |
| RS763760515 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS763761196 |
UBQLN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 15, Amyotrophic lateral sclerosis type 15 |
| RS763761460 |
TMPRSS15
|
Health Risk |
Pathogenic |
— |
| RS763762899 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Micrognathia, Hypotonia |
| RS763764130 |
NR2E3
|
Health Risk |
Conflicting classifications of pathogenicity |
Enhanced S-cone syndrome, Enhanced S-cone syndrome |
| RS763764330 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS763764765 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica inversa, autosomal recessive |
| RS763765410 |
CTCF
|
Health Risk |
Pathogenic |
— |
| RS763765573 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS763765943 |
SLC6A19
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Neutral 1 amino acid transport defect |
| RS763766162 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS763766268 |
COL11A2
|
Health Risk |
Pathogenic |
— |
| RS763767150 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS763767937 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, Peroxisome biogenesis disorder 1A (Zellweger) |
| RS763768429 |
ABCB6
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyschromatosis universalis hereditaria 3, Familial pseudohyperkalemia |
| RS763770085 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763770414 |
NARS2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 24, Combined oxidative phosphorylation defect type 24 |