| RS763587293 |
KDM6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Kabuki syndrome 2 |
| RS763588282 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS763588317 |
ANKS6
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 16, Nephronophthisis 16 |
| RS763589221 |
HNRNPUL2
|
Health Risk |
Likely pathogenic |
HNRNPUL2-related disorder, HNRNPUL2-related disorder |
| RS763590899 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS763591247 |
PIGO
|
Health Risk |
Pathogenic |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS763591386 |
FLCN
|
Health Risk |
Pathogenic |
Birt-Hogg-Dube syndrome, Birt-Hogg-Dube syndrome |
| RS763591743 |
ABCC6
|
Health Risk |
Likely pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Autosomal recessive inherited pseudoxanthoma elasticum |
| RS763591781 |
NTRK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary insensitivity to pain with anhidrosis, Inborn genetic diseases |
| RS763593155 |
POLR1C
|
Health Risk |
Pathogenic |
Hypomyelinating leukodystrophy 11, Hypomyelinating leukodystrophy 11 |
| RS763593669 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS763594644 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Intrauterine growth retardation |
| RS763595608 |
CDH23;CDH23-AS1
|
Health Risk |
Likely pathogenic |
— |
| RS763595926 |
ADA
|
Health Risk |
Likely pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS763596301 |
EGLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrocytosis, familial |
| RS763596413 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS763596840 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS763596987 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS763598472 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS763598499 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Medulloblastoma, Gorlin syndrome |
| RS763599850 |
DES
|
Health Risk |
Conflicting classifications of pathogenicity |
Desmin-related myofibrillar myopathy, Cardiovascular phenotype |
| RS763599970 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Long QT syndrome |
| RS763600083 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS763601481 |
SCNN1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism, type IB1 |
| RS763601638 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
LRP5-related disorder, 6 conditions |
| RS763603215 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral arteriopathy, autosomal dominant |
| RS763604286 |
SLC39A5
|
Health Risk |
Pathogenic |
— |
| RS763604611 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS763604691 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS763605078 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS763605512 |
NCKAP1L
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763606858 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS763607287 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763608368 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS763608502 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS763608512 |
KRT5
|
Health Risk |
Pathogenic |
EPIDERMOLYSIS BULLOSA SIMPLEX 2D, GENERALIZED INTERMEDIATE |
| RS763608530 |
EXT1
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Multiple congenital exostosis |
| RS763608839 |
MNX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Currarino triad, Currarino triad |
| RS763608948 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763609145 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS763611527 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS763612449 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS763613910 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS763613912 |
IL2RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency due to CD25 deficiency, Immunodeficiency due to CD25 deficiency |
| RS763614356 |
ABCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual developmental disorder with poor growth and with or without seizures or ataxia, Intellectual developmental disorder with poor growth and with or without seizures or ataxia |
| RS763614519 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763614919 |
EPG5
|
Health Risk |
Pathogenic |
Vici syndrome, Vici syndrome |
| RS763615183 |
FANCL
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group L, Fanconi anemia |
| RS763615602 |
DGUOK
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 4 |
| RS763615950 |
SLC38A8
|
Health Risk |
Pathogenic/Likely pathogenic |
Foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome, Foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome |
| RS763616548 |
LARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Perrault syndrome 4, Perrault syndrome 4 |
| RS763617076 |
ZP1
|
Health Risk |
Pathogenic |
Female infertility due to zona pellucida defect, Female infertility due to zona pellucida defect |
| RS763617146 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS763619811 |
DOK7
|
Health Risk |
Likely pathogenic |
Fetal akinesia deformation sequence 3, Fetal akinesia deformation sequence 3 |
| RS763620385 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS763620441 |
SLC2A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi-Bickel syndrome, Type 2 diabetes mellitus |
| RS763621169 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS76362149 |
SLC2A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi-Bickel syndrome, SLC2A2-related disorder |
| RS763622631 |
FAM20C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Lethal osteosclerotic bone dysplasia |
| RS763623409 |
CFAP410
|
Health Risk |
Pathogenic |
Axial spondylometaphyseal dysplasia, Retinal dystrophy with or without macular staphyloma |
| RS763624515 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763624831 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Charcot-Marie-Tooth disease dominant intermediate B |
| RS763625309 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiomyopathy |
| RS763625583 |
SLC27A4
|
Health Risk |
Pathogenic |
— |
| RS763625913 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS763626059 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 65, Developmental and epileptic encephalopathy |
| RS763626643 |
ANOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 1 with or without anosmia, Inborn genetic diseases |
| RS763626782 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia complementation group A |
| RS763627695 |
KCNQ4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763629092 |
RSPRY1
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive spondyloepimetaphyseal dysplasia-short stature-short fourth metatarsals-intellectual disability syndrome, Progressive spondyloepimetaphyseal dysplasia-short stature-short fourth metatarsals-intellectual disability syndrome |
| RS763629262 |
LRIT3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763629416 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS763630775 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS763631876 |
TECRL
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS763632781 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS763632823 |
TRAPPC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autism spectrum disorder |
| RS763633152 |
CLCN1
|
Health Risk |
Pathogenic |
Congenital myotonia, autosomal dominant form |
| RS763637617 |
ATP2A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Acrokeratosis verruciformis of Hopf, Acrokeratosis verruciformis of Hopf |
| RS763638795 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763639137 |
ERCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, Xeroderma pigmentosum |
| RS763639161 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS763639231 |
BRCA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary breast ovarian cancer syndrome, 8 conditions |
| RS763639520 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS763639530 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS763639737 |
PKP2
|
Health Risk |
Pathogenic |
Arrhythmogenic right ventricular dysplasia 9, Arrhythmogenic right ventricular cardiomyopathy |
| RS763639767 |
CSPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 21, Joubert syndrome 21 |
| RS763640657 |
ABCG8
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS763640926 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myotonia, autosomal dominant form |
| RS763641118 |
B3GALNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a |
| RS763642189 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS763643471 |
MORC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2Z, Inborn genetic diseases |
| RS763645041 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS763645251 |
BCKDHB
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease |
| RS763645511 |
EPHB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Lymphatic malformation 7, Cardiovascular phenotype |
| RS763646234 |
IL12RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency, Inborn genetic diseases |
| RS763647876 |
SUN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy, Emery-Dreifuss muscular dystrophy |
| RS763647934 |
MC1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Melanoma, cutaneous malignant |
| RS763648121 |
TYR
|
Health Risk |
Likely pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1A |
| RS763648933 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763649250 |
SPINK5
|
Health Risk |
Pathogenic |
Ichthyosis linearis circumflexa, Ichthyosis linearis circumflexa |