| RS763403897 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS763404256 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1G |
| RS763404712 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS763405163 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS763406021 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS763407068 |
ANKRD11
|
Health Risk |
Pathogenic |
KBG syndrome, KBG syndrome |
| RS763407931 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS763407938 |
ASL
|
Health Risk |
Pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS763408652 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Macular degeneration |
| RS763408801 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS763408993 |
G6PC3
|
Health Risk |
Likely pathogenic |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
| RS763409550 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile cortical hyperostosis, Osteogenesis imperfecta |
| RS763409574 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS763409720 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS763410987 |
CAD
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 50 |
| RS763411017 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763411938 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS763413441 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS763413580 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Congenital multicore myopathy with external ophthalmoplegia |
| RS763413730 |
SPG7
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS763414376 |
ANKRD11
|
Health Risk |
Likely pathogenic |
ANKRD11-related disorder, ANKRD11-related disorder |
| RS763416852 |
PINK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive early-onset Parkinson disease 6, Autosomal recessive early-onset Parkinson disease 6 |
| RS763416913 |
CNGB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS763418390 |
ALDH7A1
|
Health Risk |
Likely pathogenic |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS763418954 |
POLG
|
Health Risk |
Pathogenic |
— |
| RS763422682 |
IVD
|
Health Risk |
Pathogenic/Likely pathogenic |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS763422772 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS763423294 |
GFM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1, Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 |
| RS763425007 |
CC2D2A
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS763426415 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS763426689 |
ZNF687
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763427538 |
GDAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4A, Inborn genetic diseases |
| RS763428520 |
STX1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy with febrile seizures plus, type 9 |
| RS763428801 |
PGM1
|
Health Risk |
Pathogenic |
PGM1-congenital disorder of glycosylation, Inborn genetic diseases |
| RS763429317 |
TPM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy 23, Arthrogryposis |
| RS763432574 |
RAD50
|
Health Risk |
Likely pathogenic |
Nijmegen breakage syndrome-like disorder, Nijmegen breakage syndrome-like disorder |
| RS763433145 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS763433647 |
PC
|
Health Risk |
Likely pathogenic |
Pyruvate carboxylase deficiency, Pyruvate carboxylase deficiency |
| RS76343591 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Congenital hypothyroidism |
| RS763436882 |
GRIN2B
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal dominant 6 |
| RS763437121 |
CYP27B1
|
Health Risk |
Pathogenic |
Vitamin D-dependent rickets, type 1A |
| RS763437650 |
RPE65
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 20, Leber congenital amaurosis 2 |
| RS763438353 |
NMNAT1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 9, Leber congenital amaurosis 9 |
| RS763438739 |
KMT2C
|
Health Risk |
Pathogenic |
Kleefstra syndrome 2, Kleefstra syndrome 2 |
| RS763439987 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763440221 |
ALS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 2, juvenile |
| RS763440781 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS763440821 |
KMT2D
|
Health Risk |
Likely pathogenic |
Kabuki syndrome 1, Kabuki syndrome 1 |
| RS763440838 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS763441352 |
PCARE
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS763443113 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS763443331 |
QRSL1
|
Health Risk |
Pathogenic |
Cardiomyopathy, mitochondrial |
| RS763443434 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS763444110 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS763444295 |
MKS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS763445509 |
ELP1
|
Health Risk |
Pathogenic |
Familial dysautonomia, Familial dysautonomia |
| RS763446963 |
KCNQ3
|
Health Risk |
Conflicting classifications of pathogenicity |
Benign neonatal seizures, Benign neonatal seizures |
| RS763447325 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS763447736 |
TG
|
Health Risk |
Pathogenic |
— |
| RS763448297 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS76344857 |
PRKAR1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Marbach-Schaaf neurodevelopmental syndrome, Marbach-Schaaf neurodevelopmental syndrome |
| RS763448911 |
HOXB13
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, HOXB13-related disorder |
| RS763449097 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Saldino-Mainzer syndrome |
| RS763449629 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan Syndrome/Loeys-Dietz Syndrome/Familial Thoracic Aortic Aneurysms and Dissections, Marfan syndrome |
| RS763449646 |
CAPN3
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS763449647 |
MICU1
|
Health Risk |
Pathogenic |
— |
| RS763450239 |
CSTB
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS763451208 |
CPS1
|
Health Risk |
Likely pathogenic |
Pulmonary hypertension, neonatal |
| RS763451792 |
SERPING1
|
Health Risk |
Pathogenic |
Hereditary angioedema type 1, Hereditary angioedema type 1 |
| RS763452347 |
TMEM237
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 14, Joubert syndrome 14 |
| RS763452490 |
TUBGCP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pachygyria, microcephaly |
| RS763453097 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Rothmund-Thomson syndrome type 2 |
| RS763455650 |
FBRSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763455928 |
ALS2
|
Health Risk |
Likely pathogenic |
Infantile-onset ascending hereditary spastic paralysis, Amyotrophic lateral sclerosis type 2 |
| RS763456705 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS763456750 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS763456921 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS763457015 |
EXOSC9
|
Health Risk |
Pathogenic |
— |
| RS763457172 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS763457176 |
ENPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
ENPP1-related disorder, ENPP1-related disorder |
| RS763457259 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile hypophosphatasia, Adult hypophosphatasia |
| RS763458490 |
F7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital factor VII deficiency, Myocardial infarction |
| RS763458922 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS763459034 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS763459576 |
PEX6
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder, Zellweger spectrum disorders |
| RS763459814 |
APC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763459820 |
TPO
|
Health Risk |
Pathogenic |
— |
| RS763461489 |
ATXN3
|
Health Risk |
Conflicting classifications of pathogenicity |
ATXN3-related disorder, Azorean disease |
| RS763462242 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS763462603 |
KCNQ1
|
Health Risk |
Pathogenic/Likely pathogenic |
Long QT syndrome 1, Cardiovascular phenotype |
| RS763462686 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinase-positive oculocutaneous albinism, Tyrosinase-positive oculocutaneous albinism |
| RS763462869 |
NFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
NFS1-related disorder, NFS1-related disorder |
| RS763463859 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS763465373 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS763468558 |
ALOX12B
|
Health Risk |
Pathogenic |
Autosomal recessive congenital ichthyosis 2, Lamellar ichthyosis |
| RS763468767 |
GSDME
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 5, Autosomal dominant nonsyndromic hearing loss 5 |
| RS763469132 |
MAP2K2
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS763469367 |
TRDN
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 5, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS763469464 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS763470078 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |