| RS763649825 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS763651145 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
CREBBP-related disorder, Inborn genetic diseases |
| RS763651232 |
CRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 2, Retinitis pigmentosa |
| RS763651353 |
BCOR
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculofaciocardiodental syndrome, Inborn genetic diseases |
| RS763651849 |
LIPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolman disease, Cardiovascular phenotype |
| RS763652056 |
DSP
|
Health Risk |
Pathogenic |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS763652784 |
AGL
|
Health Risk |
Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS763653429 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS763654348 |
VPS13A
|
Health Risk |
Pathogenic/Likely pathogenic |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS763654373 |
TEX15
|
Health Risk |
Pathogenic |
Spermatogenic failure 25, Spermatogenic failure 25 |
| RS763654582 |
BIVM-ERCC5;ERCC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ovarian cancer, Ovarian cancer |
| RS763654639 |
POLH
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum variant type, See cases |
| RS763655714 |
SRP72
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant aplasia and myelodysplasia, SRP72-related disorder |
| RS763655831 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS763656384 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763656507 |
MUSK
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 9, Fetal akinesia deformation sequence 1 |
| RS763656985 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS763657340 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS763658299 |
RMND1
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation defect type 11, Combined oxidative phosphorylation defect type 11 |
| RS763659581 |
MYOM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS763662038 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS763662108 |
GALT
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase, Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase |
| RS763662774 |
TPO
|
Health Risk |
Pathogenic |
Deficiency of iodide peroxidase, Deficiency of iodide peroxidase |
| RS763664351 |
IL17RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 51, Immunodeficiency 51 |
| RS763665120 |
IVD
|
Health Risk |
Likely pathogenic |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS763668057 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS763668385 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS763668545 |
NPHP4
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS763668912 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS763669136 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS763669401 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Hereditary spastic paraplegia 30 |
| RS763670106 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS763670176 |
DYNC2I2
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 11 with or without polydactyly, Inborn genetic diseases |
| RS763670204 |
SEMA4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS763670293 |
ADGRV1
|
Health Risk |
Pathogenic/Likely pathogenic |
Monogenic hearing loss, Febrile seizures |
| RS763671258 |
GYS2
|
Health Risk |
Pathogenic |
Glycogen storage disorder due to hepatic glycogen synthase deficiency, Glycogen storage disorder due to hepatic glycogen synthase deficiency |
| RS763671264 |
RPGRIP1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 6, Cone-rod dystrophy 13 |
| RS763671728 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS763671755 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763672163 |
MRPS34
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation deficiency 32, Inborn genetic diseases |
| RS763673114 |
TPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of iodide peroxidase, Deficiency of iodide peroxidase |
| RS763674597 |
DYSF
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS763674655 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS763675499 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS763676031 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS763676435 |
BUB1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Mosaic variegated aneuploidy syndrome 1, Inborn genetic diseases |
| RS763677632 |
TRPM1
|
Health Risk |
Likely pathogenic |
— |
| RS763677869 |
WFS1
|
Health Risk |
Pathogenic |
Autosomal dominant nonsyndromic hearing loss 6, Type 2 diabetes mellitus |
| RS763678034 |
GNPTG
|
Health Risk |
Pathogenic |
GNPTG-mucolipidosis, GNPTG-mucolipidosis |
| RS763678131 |
CYBA
|
Health Risk |
Pathogenic |
Granulomatous disease, chronic |
| RS763678756 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS763679404 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, Charcot-Marie-Tooth disease type 2 |
| RS763679435 |
TSHR
|
Health Risk |
Pathogenic |
— |
| RS763679772 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Adams-Oliver syndrome 5 |
| RS763680697 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Mitochondrial complex II deficiency |
| RS763680884 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS763682832 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS763683012 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS763685190 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS763685245 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Gastric cancer |
| RS763685410 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS763685455 |
TRNT1
|
Health Risk |
Pathogenic |
Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome, Retinal dystrophy |
| RS763685504 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS763685772 |
RPGRIP1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS763685989 |
ATAD3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763686798 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS763687804 |
CLPP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763688228 |
MMP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Metaphyseal anadysplasia 2, Metaphyseal anadysplasia 2 |
| RS763688567 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS763690279 |
FMO3
|
Health Risk |
Pathogenic |
— |
| RS763690339 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS763693540 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS763694069 |
RLBP1
|
Health Risk |
Pathogenic/Likely pathogenic |
RLBP1-related disorder, Retinitis pigmentosa |
| RS763694865 |
PSAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
PSAT deficiency, Neu-Laxova syndrome 2 |
| RS763695196 |
SBF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763695515 |
AIRE
|
Health Risk |
Pathogenic/Likely pathogenic |
Polyglandular autoimmune syndrome, type 1 |
| RS763696297 |
WDR73
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Galloway-Mowat syndrome 1 |
| RS763696416 |
COG5
|
Health Risk |
Conflicting classifications of pathogenicity |
COG5-congenital disorder of glycosylation, COG5-congenital disorder of glycosylation |
| RS763697798 |
VPS35
|
Health Risk |
Conflicting classifications of pathogenicity |
Parkinson disease 17, Parkinson disease 17 |
| RS763697898 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal macular dystrophy type 2, Retinitis pigmentosa |
| RS763699437 |
SMCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Facioscapulohumeral muscular dystrophy 2, Facioscapulohumeral muscular dystrophy 2 |
| RS763699668 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 27 |
| RS763700481 |
PSMB10
|
Health Risk |
Pathogenic |
Proteasome-associated autoinflammatory syndrome 5, Proteasome-associated autoinflammatory syndrome 5 |
| RS763701580 |
ERCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Corpus callosum, agenesis of |
| RS763702846 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS763703697 |
BIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, centronuclear |
| RS763704831 |
SPEG
|
Health Risk |
Likely pathogenic |
Myopathy, centronuclear |
| RS763705074 |
LSS
|
Health Risk |
Pathogenic |
Alopecia-intellectual disability syndrome 4, Alopecia-intellectual disability syndrome 4 |
| RS763705148 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS763705904 |
SLC13A3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS763706390 |
NR2E3
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 37, Enhanced S-cone syndrome |
| RS763706988 |
DGUOK
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial DNA depletion syndrome 3 (hepatocerebral type), DGUOK-related disorder |
| RS763707275 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS763708665 |
HPS4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 4, Hermansky-Pudlak syndrome 4 |
| RS763709094 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, IFT140-related disorder |
| RS763709302 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS763709592 |
POC1A
|
Health Risk |
Pathogenic |
POC1A-related syndrome, POC1A-related syndrome |
| RS763709773 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS763710252 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stargardt disease 4, Cone-rod dystrophy 12 |
| RS76371115 |
CFTR
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystic fibrosis, Bronchiectasis with or without elevated sweat chloride 1 |