| RS752071055 |
ADAMTSL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Geleophysic dysplasia 1, Connective tissue dysplasia |
| RS752071309 |
TET2
|
Health Risk |
Pathogenic |
— |
| RS752071569 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS752073942 |
KCNQ2
|
Health Risk |
Likely pathogenic |
— |
| RS752074255 |
SGCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonic dystonia 11, SGCE-related disorder |
| RS752074481 |
DTNBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome |
| RS752075131 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS752076094 |
FUS
|
Health Risk |
Likely pathogenic |
— |
| RS752076372 |
RHO
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 4, Retinitis pigmentosa 4 |
| RS75207686 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS752077073 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS752077571 |
CCDC78
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy with internal nuclei and atypical cores, Inborn genetic diseases |
| RS752078094 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism type 2C, Neuropathy |
| RS752078357 |
DNAJB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS752078407 |
PANK2
|
Health Risk |
Pathogenic |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS752079977 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS752080248 |
POLH
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum variant type, Xeroderma pigmentosum variant type |
| RS752080701 |
TP63
|
Health Risk |
Pathogenic |
Premature ovarian insufficiency, Premature ovarian failure 21 |
| RS752080876 |
FREM2
|
Health Risk |
Conflicting classifications of pathogenicity |
FREM2-related disorder, FREM2-related disorder |
| RS752081680 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS752081909 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS752082232 |
PDHA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate dehydrogenase E1-alpha deficiency, Pyruvate dehydrogenase E1-alpha deficiency |
| RS752082912 |
CNNM4
|
Health Risk |
Pathogenic |
— |
| RS752084128 |
ALMS1
|
Health Risk |
Pathogenic |
— |
| RS752084251 |
F9
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombophilia, X-linked |
| RS752085688 |
TALDO1
|
Health Risk |
Likely pathogenic |
Deficiency of transaldolase, Deficiency of transaldolase |
| RS752086486 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752086581 |
VRK1
|
Health Risk |
Pathogenic |
Pontocerebellar hypoplasia type 1A, Pontocerebellar hypoplasia type 1A |
| RS752087954 |
HPS3
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS752088869 |
JAK3
|
Health Risk |
Conflicting classifications of pathogenicity |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, T-B+ severe combined immunodeficiency due to JAK3 deficiency |
| RS752088918 |
XPC
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group C |
| RS752089136 |
SLC4A4
|
Health Risk |
Likely pathogenic |
SLC4A4-related disorder, SLC4A4-related disorder |
| RS752090052 |
OSTM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive osteopetrosis 5, Autosomal recessive osteopetrosis 5 |
| RS752090395 |
AFG2A
|
Health Risk |
Pathogenic |
Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome, Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome |
| RS752091023 |
EFEMP1
|
Health Risk |
Conflicting classifications of pathogenicity |
EFEMP1-related disorder, EFEMP1-related disorder |
| RS752091655 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS752093604 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS752093696 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS752094174 |
VPS13D
|
Health Risk |
Likely pathogenic |
Spinocerebellar atrophy, Spinocerebellar atrophy |
| RS752094219 |
LAMA2
|
Health Risk |
Likely pathogenic |
Merosin deficient congenital muscular dystrophy, Muscular dystrophy |
| RS752094504 |
RNU4ATAC;CLASP1;CLASP1-AS1
|
Health Risk |
Conflicting classifications of pathogenicity |
CLASP1-related disorder, RNU4ATAC-related disorder |
| RS752095452 |
PRX
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4 |
| RS752095723 |
TGM6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752096360 |
SETD1B
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with seizures and language delay, Intellectual developmental disorder with seizures and language delay |
| RS752097874 |
MAGEL2
|
Health Risk |
Pathogenic/Likely pathogenic |
Schaaf-Yang syndrome, Schaaf-Yang syndrome |
| RS752098175 |
STAG3
|
Health Risk |
Likely pathogenic |
Premature ovarian failure 8, Premature ovarian failure 8 |
| RS752098612 |
TLE6
|
Health Risk |
Likely pathogenic |
Preimplantation embryonic lethality 1, Preimplantation embryonic lethality 1 |
| RS752099132 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal Kniest-like syndrome, Schwartz-Jampel syndrome |
| RS752099208 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Myopathy |
| RS752100031 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, LRP5-related disorder |
| RS752100894 |
ASL
|
Health Risk |
Pathogenic/Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS752101551 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS752101663 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS752101829 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS752102959 |
ENAM
|
Health Risk |
Pathogenic |
Amelogenesis imperfecta - hypoplastic autosomal dominant - local, Amelogenesis imperfecta - hypoplastic autosomal dominant - local |
| RS752104014 |
ACSF3
|
Health Risk |
Likely pathogenic |
— |
| RS752104654 |
SLC19A2
|
Health Risk |
Pathogenic |
Megaloblastic anemia, thiamine-responsive |
| RS752104975 |
TNFRSF6B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752104988 |
MYBPC3
|
Health Risk |
Pathogenic |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS752105563 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group A, Fanconi anemia |
| RS752106293 |
CCNO
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752107643 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS752107739 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752108301 |
SNORD118
|
Health Risk |
Pathogenic |
Leukoencephalopathy with calcifications and cysts, Leukoencephalopathy with calcifications and cysts |
| RS752108348 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS752109819 |
DYNC2I1
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 8 with or without polydactyly, Short-rib thoracic dysplasia 8 with or without polydactyly |
| RS752110126 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS75211071 |
HEXA
|
Health Risk |
Conflicting classifications of pathogenicity |
Tay-Sachs disease, Tay-Sachs disease |
| RS752112582 |
MERTK
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS752113614 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS752114168 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS752114200 |
SPTA1
|
Health Risk |
Likely pathogenic |
Pyropoikilocytosis, hereditary |
| RS752114814 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS752114855 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS752115449 |
SPAG17
|
Health Risk |
Pathogenic |
Spermatogenic failure 55, Spermatogenic failure 55 |
| RS752116341 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS752116461 |
ST3GAL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS752116741 |
CYP19A1
|
Health Risk |
Pathogenic |
— |
| RS752117651 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Skeletal dysplasia, Skeletal dysplasia |
| RS752118019 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS752118948 |
SUGCT
|
Health Risk |
Conflicting classifications of pathogenicity |
Glutaryl-CoA oxidase deficiency, Glutaryl-CoA oxidase deficiency |
| RS752119263 |
ETFA
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS752119540 |
GPI
|
Health Risk |
Likely pathogenic |
GPI-related disorder, GPI-related disorder |
| RS752120059 |
XPC
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group C |
| RS752120730 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS752121953 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS752122764 |
SETX
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Spinocerebellar ataxia |
| RS752123968 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, LYST-related disorder |
| RS752124839 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiovascular phenotype |
| RS752125512 |
BEST1
|
Health Risk |
Pathogenic/Likely pathogenic |
Vitelliform macular dystrophy 2, Autosomal dominant vitreoretinochoroidopathy |
| RS752126122 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS752126515 |
FANCA
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia complementation group A |
| RS752127949 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS752129019 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiomyopathy |
| RS752129360 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS752129504 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752130196 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 1, Cardiac arrhythmia |
| RS752130338 |
COQ8A
|
Health Risk |
Pathogenic |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS752131463 |
NAGLU
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Mucopolysaccharidosis |
| RS752131830 |
INPPL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |