| RS752131891 |
CDH3
|
Health Risk |
Pathogenic |
Congenital hypotrichosis with juvenile macular dystrophy, Congenital hypotrichosis with juvenile macular dystrophy |
| RS752132275 |
EXT2
|
Health Risk |
Likely pathogenic |
Exostoses, multiple |
| RS752134549 |
RSRC2
|
Health Risk |
Likely pathogenic |
6 conditions, 6 conditions |
| RS752134669 |
SLC34A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive hypophosphatemic bone disease, Autosomal recessive hypophosphatemic bone disease |
| RS752134753 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS752134900 |
RSPH3
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 32, Primary ciliary dyskinesia 32 |
| RS752135143 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS752135269 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS752135284 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperkalemic periodic paralysis, Hyperkalemic periodic paralysis |
| RS752135996 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS752136178 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS752136581 |
CIC
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital cerebellar hypoplasia, Congenital cerebellar hypoplasia |
| RS752136594 |
FANCM
|
Health Risk |
Likely pathogenic |
Hereditary breast ovarian cancer syndrome, Hereditary breast ovarian cancer syndrome |
| RS752137335 |
TYMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS752137434 |
CFAP410
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy with or without macular staphyloma |
| RS752137615 |
HMGCL
|
Health Risk |
Pathogenic |
Deficiency of hydroxymethylglutaryl-CoA lyase, Deficiency of hydroxymethylglutaryl-CoA lyase |
| RS752137856 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Dilated cardiomyopathy 1G |
| RS752137872 |
EEF1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 33 |
| RS752138290 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Macular degeneration |
| RS752140135 |
CEP135
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly 8, primary |
| RS752141197 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Amyotrophic lateral sclerosis type 4 |
| RS752141701 |
TMEM231
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 20, Meckel syndrome |
| RS752141860 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752142489 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS752143061 |
FDXR
|
Health Risk |
Pathogenic/Likely pathogenic |
Auditory neuropathy-optic atrophy syndrome, Inborn genetic diseases |
| RS752143388 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS752143706 |
SLC2A1
|
Health Risk |
Likely pathogenic |
— |
| RS752144368 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS752144775 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ventricular tachycardia, Cardiomyopathy |
| RS752145071 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome 3b, autosomal recessive |
| RS752145775 |
GFM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752145794 |
PEPD
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS752147287 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Nephronophthisis |
| RS752147871 |
ABCA4
|
Health Risk |
Likely pathogenic |
Severe early-childhood-onset retinal dystrophy, Age related macular degeneration 2 |
| RS752148586 |
SMPD1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type A |
| RS752148857 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752149463 |
AUH
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria type 1, AUH-related disorder |
| RS752149683 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS752150024 |
RTTN
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS752150323 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS752150906 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS752151031 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS752152002 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS752152148 |
APC
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial adenomatous polyposis 1, Familial adenomatous polyposis 1 |
| RS752152305 |
SLC26A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis, type IB |
| RS752152483 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS752153225 |
ACAD8
|
Health Risk |
Likely pathogenic |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS752153829 |
HGD
|
Health Risk |
Pathogenic |
Alkaptonuria, Alkaptonuria |
| RS752155273 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS752155450 |
SLC12A6
|
Health Risk |
Likely pathogenic |
Agenesis of the corpus callosum with peripheral neuropathy, Agenesis of the corpus callosum with peripheral neuropathy |
| RS752155690 |
CAPN3
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS752156383 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752156505 |
SELENON
|
Health Risk |
Pathogenic/Likely pathogenic |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS752158933 |
GANAB
|
Health Risk |
Pathogenic/Likely pathogenic |
POLYCYSTIC KIDNEY DISEASE 3 WITH POLYCYSTIC LIVER DISEASE, Polycystic kidney disease 3 with or without polycystic liver disease |
| RS752159625 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 16, Hypokalemic periodic paralysis |
| RS752159793 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS752159903 |
CWC27
|
Health Risk |
Pathogenic |
Metaphyseal chondrodysplasia-retinitis pigmentosa syndrome, Retinal dystrophy |
| RS752160342 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Chédiak-Higashi syndrome |
| RS752160946 |
ABCA4
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 19, Retinitis pigmentosa 19 |
| RS752160950 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS752162999 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS752163032 |
SLC38A8
|
Health Risk |
Pathogenic |
— |
| RS752163457 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 3, Jeune thoracic dystrophy |
| RS752164207 |
CYP17A1
|
Health Risk |
Likely pathogenic |
Deficiency of steroid 17-alpha-monooxygenase, Deficiency of steroid 17-alpha-monooxygenase |
| RS752164603 |
TPP1
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 2, Neuronal ceroid lipofuscinosis |
| RS752164796 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS752168132 |
SGCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2E, Autosomal recessive limb-girdle muscular dystrophy type 2E |
| RS752169336 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752169625 |
SELENON
|
Health Risk |
Conflicting classifications of pathogenicity |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS752169967 |
ALDH3A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752170592 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS752170606 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Cardiovascular phenotype |
| RS752171066 |
TMEM107
|
Health Risk |
Pathogenic |
Orofaciodigital syndrome 16, Orofaciodigital syndrome |
| RS752173491 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Cardiomyopathy |
| RS752175052 |
RPGRIP1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 6, Cone-rod dystrophy 13 |
| RS752176040 |
TMCO1
|
Health Risk |
Pathogenic/Likely pathogenic |
Craniofacial dysmorphism, skeletal anomalies |
| RS752176305 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS752176414 |
ALOX12B
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 2, Lamellar ichthyosis |
| RS752177002 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile GM1 gangliosidosis, GM1 gangliosidosis |
| RS752177240 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Heimler syndrome 2, Peroxisome biogenesis disorder |
| RS752177472 |
LRSAM1
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2P, LRSAM1-related disorder |
| RS752177638 |
DLL1
|
Health Risk |
Pathogenic |
— |
| RS752178081 |
EHMT1
|
Health Risk |
Likely pathogenic |
— |
| RS752178257 |
LARP7
|
Health Risk |
Pathogenic |
Microcephalic primordial dwarfism, Alazami type |
| RS752179149 |
ADGRV1
|
Health Risk |
Pathogenic |
Retinal dystrophy, Usher syndrome type 2C |
| RS752179828 |
SPINK5
|
Health Risk |
Pathogenic/Likely pathogenic |
Netherton syndrome, Ichthyosis linearis circumflexa |
| RS752179960 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752180110 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Charcot-Marie-Tooth disease dominant intermediate E |
| RS752180212 |
CTNS
|
Health Risk |
Pathogenic |
Nephropathic cystinosis, Ocular cystinosis |
| RS75218052 |
SLC2A10
|
Health Risk |
Conflicting classifications of pathogenicity |
Arterial tortuosity syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS752180749 |
PEX10
|
Health Risk |
Pathogenic |
Peroxisome biogenesis disorder, complementation group 7 |
| RS752181922 |
COL9A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Inborn genetic diseases |
| RS752183158 |
LAMA2
|
Health Risk |
Likely pathogenic |
— |
| RS752184595 |
ERCC6L2
|
Health Risk |
Pathogenic |
— |
| RS752184633 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial focal epilepsy with variable foci, Inborn genetic diseases |
| RS752185152 |
ESPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, ESPN-related disorder |
| RS752188036 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS752188418 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Transitory neonatal diabetes mellitus, Maturity-onset diabetes of the young |
| RS752189445 |
ERCC6L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752189808 |
ALG1
|
Health Risk |
Likely pathogenic |
ALG1-congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |