| RS752189896 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS752191968 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS752192006 |
FBN1
|
Health Risk |
Likely pathogenic |
Marfan syndrome, Marfan syndrome |
| RS752192642 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 11 |
| RS752192677 |
PRX
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS752192756 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, Malignant hyperthermia |
| RS752193525 |
AIPL1
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis, AIPL1-related retinopathy |
| RS752193945 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS752194597 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752194694 |
GPC3
|
Health Risk |
Pathogenic |
Wilms tumor 1, Wilms tumor 1 |
| RS752195182 |
ANGPTL3
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS752196801 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS752197557 |
LRP2
|
Health Risk |
Likely pathogenic |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS752197734 |
CEP290
|
Health Risk |
Pathogenic |
Retinal dystrophy, Bardet-Biedl syndrome 14 |
| RS752197838 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS752198747 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS752199191 |
RYR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital multicore myopathy with external ophthalmoplegia, RYR1-related disorder |
| RS752199848 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752200108 |
TTI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752200396 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS752201516 |
OTOF
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS752201545 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Macular degeneration |
| RS752201749 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS752202089 |
BBS12
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 12 |
| RS752202315 |
WRN
|
Health Risk |
Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS752203227 |
MCM3AP
|
Health Risk |
Likely pathogenic |
— |
| RS752203346 |
CUL7
|
Health Risk |
Pathogenic |
— |
| RS752203499 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS752203815 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752204035 |
KLF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital dyserythropoietic anemia type 4, FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 6 |
| RS752204728 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS752205161 |
MMACHC
|
Health Risk |
Pathogenic/Likely pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS752205220 |
GRM6
|
Health Risk |
Pathogenic |
GRM6-related disorder, GRM6-related disorder |
| RS752206117 |
SALL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Townes syndrome, Inborn genetic diseases |
| RS752206330 |
ARSA
|
Health Risk |
Likely pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS752207334 |
CEP63
|
Health Risk |
Conflicting classifications of pathogenicity |
Seckel syndrome 6, Familial cancer of breast |
| RS752207572 |
SPEN
|
Health Risk |
Pathogenic |
Radio-Tartaglia syndrome, Radio-Tartaglia syndrome |
| RS752207581 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752208167 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS752208304 |
SHOX
|
Health Risk |
Pathogenic |
Leri-Weill dyschondrosteosis, Leri-Weill dyschondrosteosis |
| RS752208389 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Idiopathic hypereosinophilic syndrome |
| RS752208462 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS752209038 |
REEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 72, Inborn genetic diseases |
| RS752209909 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS752212030 |
CLN6
|
Health Risk |
Pathogenic |
Ceroid lipofuscinosis, neuronal |
| RS752212361 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Lynch syndrome, Hereditary cancer-predisposing syndrome |
| RS752212460 |
AGRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 8, Inborn genetic diseases |
| RS752212470 |
CRB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 8, Retinitis pigmentosa 12 |
| RS752213208 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS752213778 |
TXNRD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Cardiovascular phenotype |
| RS752216720 |
ACAT1
|
Health Risk |
Pathogenic |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS752216863 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS752216964 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome with C3 anomaly, Complement component 3 deficiency |
| RS752217760 |
COL2A1
|
Health Risk |
Pathogenic |
— |
| RS752218005 |
SLC52A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Brown-Vialetto-van Laere syndrome 1, Brown-Vialetto-van Laere syndrome 1 |
| RS752218424 |
WDFY3
|
Health Risk |
Pathogenic |
Neurodevelopmental delay, Neurodevelopmental delay |
| RS752218712 |
ROR2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752219487 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, Maturity-onset diabetes of the young |
| RS752219824 |
MPDZ
|
Health Risk |
Pathogenic |
— |
| RS752219939 |
COQ9
|
Health Risk |
Likely pathogenic |
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Lung cancer |
| RS752220849 |
MTR
|
Health Risk |
Pathogenic |
Methylcobalamin deficiency type cblG, Methylcobalamin deficiency type cblG |
| RS752221563 |
GABRB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, childhood absence |
| RS752222200 |
SLC34A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive hypophosphatemic bone disease, Autosomal recessive hypophosphatemic bone disease |
| RS752222356 |
DNMT3A
|
Health Risk |
Pathogenic |
Tatton-Brown-Rahman overgrowth syndrome, Tatton-Brown-Rahman overgrowth syndrome |
| RS752222583 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hyperinsulinism, Transitory neonatal diabetes mellitus |
| RS752222954 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS752223388 |
ADAMTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS752223599 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS752223894 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS752224921 |
SYNE1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive ataxia, Beauce type |
| RS752225290 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS752226674 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752226947 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS752227380 |
SHANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752228025 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS752228470 |
RYR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS752229468 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2O, Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability) |
| RS752229880 |
MAN2B1
|
Health Risk |
Likely pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS752230253 |
CERS3
|
Health Risk |
Pathogenic |
Lamellar ichthyosis, Lamellar ichthyosis |
| RS752230428 |
CLDN16
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Primary hypomagnesemia |
| RS752231020 |
TTC19
|
Health Risk |
Likely pathogenic |
Mitochondrial complex III deficiency nuclear type 2, Mitochondrial complex III deficiency nuclear type 2 |
| RS752231547 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752232293 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS752232419 |
OCA2
|
Health Risk |
Pathogenic |
— |
| RS752232501 |
COG6
|
Health Risk |
Conflicting classifications of pathogenicity |
COG6-congenital disorder of glycosylation, COG6-related disorder |
| RS752232577 |
CP
|
Health Risk |
Pathogenic |
Deficiency of ferroxidase, Deficiency of ferroxidase |
| RS752232600 |
PGM1
|
Health Risk |
Conflicting classifications of pathogenicity |
PGM1-congenital disorder of glycosylation, PGM1-congenital disorder of glycosylation |
| RS752232718 |
FH
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Fumarase deficiency |
| RS752232888 |
KCNH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zimmermann-Laband syndrome 1, Temple-Baraitser syndrome |
| RS752233230 |
CPA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Febrile seizures, familial |
| RS752233745 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS752234195 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS752238132 |
SIX5
|
Health Risk |
Conflicting classifications of pathogenicity |
SIX5-related disorder, Branchiootorenal syndrome 2 |
| RS752238353 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS752239703 |
SERAC1
|
Health Risk |
Pathogenic |
3-methylglutaconic aciduria with deafness, encephalopathy |
| RS752241086 |
GRIN2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS752241342 |
SMARCAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS752241362 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS752241422 |
DCLRE1C
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency due to DCLRE1C deficiency, Severe combined immunodeficiency due to DCLRE1C deficiency |
| RS752242512 |
RDH12
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 13, Leber congenital amaurosis |