| RS730882262 |
LMNA
|
Health Risk |
Likely pathogenic |
Right ventricular cardiomyopathy, Hutchinson-Gilford progeria syndrome |
| RS73090721 |
USH2A
|
Health Risk |
Pathogenic |
Rare genetic deafness, Retinitis pigmentosa 39 |
| RS73095427 |
IBA57
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple mitochondrial dysfunctions syndrome 3, Multiple mitochondrial dysfunctions syndrome 3 |
| RS73102625 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS73113975 |
ARFGEF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Periventricular heterotopia with microcephaly, autosomal recessive |
| RS73148633 |
VCAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS73155056 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS73165082 |
TNRC6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS73167107 |
NAGA
|
Health Risk |
Conflicting classifications of pathogenicity |
Alpha-N-acetylgalactosaminidase deficiency type 1, Alpha-N-acetylgalactosaminidase deficiency type 2 |
| RS73167274 |
DYNC2I1
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 8 with or without polydactyly, DYNC2I1-related disorder |
| RS73169186 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS73174429 |
SHANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, SHANK3-related disorder |
| RS73184339 |
ALG11;UTP14C
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG11-congenital disorder of glycosylation, ALG11-congenital disorder of glycosylation |
| RS73192874 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Senior-Loken syndrome 6, Bardet-Biedl syndrome 14 |
| RS73196003 |
HLCS
|
Health Risk |
Conflicting classifications of pathogenicity |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS73198165 |
EVC2
|
Health Risk |
Pathogenic |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS73215912 |
CFTR
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS73221409 |
DNAH10
|
Health Risk |
Conflicting classifications of pathogenicity |
DNAH10-related disorder, DNAH10-related disorder |
| RS73226383 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS73262683 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS73265454 |
SIL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marinesco-Sjögren syndrome, Marinesco-Sjögren syndrome |
| RS73273219 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Inborn genetic diseases |
| RS73276691 |
ZFYVE26
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 15, Hereditary spastic paraplegia 15 |
| RS73277593 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS73302197 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS73309461 |
SIX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 23, Branchiootic syndrome 3 |
| RS73312829 |
GALC
|
Health Risk |
Conflicting classifications of pathogenicity |
Galactosylceramide beta-galactosidase deficiency, Inborn genetic diseases |
| RS73323465 |
GNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-D |
| RS73342245 |
TSHR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hyperthyroidism due to mutations in TSH receptor, Hypothyroidism due to TSH receptor mutations |
| RS73343752 |
PSPH
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of phosphoserine phosphatase, Deficiency of phosphoserine phosphatase |
| RS73344082 |
MARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2U, Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency |
| RS73360282 |
TMTC2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS73375345 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS73407163 |
DNHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
DNHD1-related disorder, DNHD1-related disorder |
| RS73415876 |
SOX10
|
Health Risk |
Pathogenic |
Waardenburg syndrome type 4C, Waardenburg syndrome type 4C |
| RS73423036 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Transitory neonatal diabetes mellitus |
| RS73423037 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Permanent neonatal diabetes mellitus, Hyperinsulinemic hypoglycemia |
| RS73464271 |
CNTNAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cortical dysplasia-focal epilepsy syndrome, Inborn genetic diseases |
| RS73464952 |
VWA8
|
Health Risk |
Likely pathogenic |
Nonsyndromic cleft lip palate, Nonsyndromic cleft lip palate |
| RS73475744 |
NDP
|
Health Risk |
Conflicting classifications of pathogenicity |
History of neurodevelopmental disorder, History of neurodevelopmental disorder |
| RS73505420 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group P |
| RS73517551 |
MRE11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia-like disorder |
| RS735239 |
CD209
|
Health Risk |
risk factor |
Mycobacterium tuberculosis, susceptibility to |
| RS73532636 |
LAMA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1JJ |
| RS73541508 |
ENPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Arterial calcification, generalized |
| RS73549518 |
HR
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrichia with papular lesions, Alopecia universalis congenita |
| RS73549580 |
BMP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Inborn genetic diseases |
| RS7355450 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS73569592 |
HGSNAT
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS73580047 |
RNF217
|
Health Risk |
risk factor |
Multiple sclerosis, susceptibility to |
| RS73589395 |
GAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Giant axonal neuropathy 1, Inborn genetic diseases |
| RS73636611 |
SRPX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Rolandic epilepsy, intellectual disability |
| RS73637412 |
GPR101
|
Health Risk |
Conflicting classifications of pathogenicity |
Pituitary adenoma, growth hormone-secreting |
| RS73663163 |
BLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Systemic lupus erythematosus, Maturity-onset diabetes of the young type 11 |
| RS737054 |
FKBP5
|
Health Risk |
Likely risk allele |
Susceptibility to severe depressive disorder, Susceptibility to severe depressive disorder |
| RS73714410 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS73715573 |
CFTR
|
Health Risk |
Pathogenic/Likely pathogenic; other |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS73717525 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS737267 |
SLC2A9
|
Health Risk |
association |
Uric acid concentration, serum |
| RS7374804 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS73749732 |
PGM3
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 23, PGM3-related disorder |
| RS73754255 |
NDUFS4
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Mitochondrial complex I deficiency |
| RS73764462 |
TRAF3IP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Candidiasis, familial |
| RS73779334 |
SUMO4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS73783802 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, MEGF10-related myopathy |
| RS73790880 |
HSD17B4
|
Health Risk |
Conflicting classifications of pathogenicity |
Bifunctional peroxisomal enzyme deficiency, Perrault syndrome |
| RS73807328 |
PROP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pituitary hormone deficiency, combined |
| RS73810366 |
PHOX2B
|
Health Risk |
Pathogenic |
Haddad syndrome, Congenital central hypoventilation |
| RS73830668 |
FYCO1
|
Health Risk |
Pathogenic |
Cataract 18, Cataract 18 |
| RS738409 |
PNPLA3
|
Health Risk |
Conflicting classifications of pathogenicity; risk factor |
NAFLD1, Hepatic steatosis |
| RS73846070 |
PROS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombophilia due to protein S deficiency, autosomal recessive |
| RS73885319 |
APOL1
|
Health Risk |
Conflicting classifications of pathogenicity; risk factor |
Hyalinosis, Segmental Glomerular |
| RS73920281 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS73920284 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS73922346 |
XDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary xanthinuria type 1, Xanthinuria type II |
| RS73923958 |
FBN3
|
Health Risk |
Conflicting classifications of pathogenicity |
FBN3-related disorder, FBN3-related disorder |
| RS73925118 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS73926269 |
EPAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrocytosis, familial |
| RS73927405 |
NDUFAF7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS73928330 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish congenital nephrotic syndrome, Congenital nephrotic syndrome |
| RS73934370 |
LIM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cataract 19 multiple types, Cataract 19 multiple types |
| RS73938527 |
LAMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS73945001 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Monogenic diabetes, Alstrom syndrome |
| RS73946020 |
PIEZO2
|
Health Risk |
Conflicting classifications of pathogenicity |
autosomal recessive PIEZO2 associated disease, Arthrogryposis |
| RS739689 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Leucine-induced hypoglycemia, Hyperinsulinemic hypoglycemia |
| RS73973137 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS73973139 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1G |
| RS73980009 |
B9D1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 27, B9D1-related disorder |
| RS73982299 |
ACACA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS74006838 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS74012174 |
COG7
|
Health Risk |
Conflicting classifications of pathogenicity |
COG7 congenital disorder of glycosylation, COG7 congenital disorder of glycosylation |
| RS74015039 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental delay, hypotonia |
| RS74022458 |
MYO9A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS74029958 |
RLBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary retinal dystrophy, Newfoundland cone-rod dystrophy |
| RS74032867 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS74047012 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS74056058 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism type 2C, Neuropathy |
| RS74067193 |
RECQL
|
Health Risk |
Conflicting classifications of pathogenicity |
RECQL-related disorder, RECQL-related disorder |
| RS74070022 |
P3H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 8, Osteogenesis Imperfecta |
| RS74075638 |
C8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute myeloid leukemia, Acute myeloid leukemia |