| RS730882151 |
KIFBP
|
Health Risk |
Pathogenic |
Goldberg-Shprintzen syndrome, Goldberg-Shprintzen syndrome |
| RS730882152 |
PARS2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 75 |
| RS730882153 |
PARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 75 |
| RS730882154 |
NARS2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 24, Combined oxidative phosphorylation defect type 24 |
| RS730882155 |
NARS2
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation defect type 24, Combined oxidative phosphorylation defect type 24 |
| RS730882156 |
KITLG
|
Health Risk |
Pathogenic |
Hyperpigmentation with or without hypopigmentation, familial progressive |
| RS730882157 |
KITLG
|
Health Risk |
Pathogenic |
Hyperpigmentation with or without hypopigmentation, familial progressive |
| RS730882158 |
PRSS56
|
Health Risk |
Likely pathogenic |
Isolated microphthalmia 6, Isolated microphthalmia 6 |
| RS730882159 |
PRSS56
|
Health Risk |
Pathogenic |
Isolated microphthalmia 6, Isolated microphthalmia 6 |
| RS730882160 |
PRSS56
|
Health Risk |
Pathogenic |
Isolated microphthalmia 6, Isolated microphthalmia 6 |
| RS730882161 |
PRSS56
|
Health Risk |
Pathogenic |
Isolated microphthalmia 6, Isolated microphthalmia 6 |
| RS730882162 |
PRSS56
|
Health Risk |
Likely pathogenic |
Isolated microphthalmia 6, Isolated microphthalmia 6 |
| RS730882164 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS730882165 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS730882166 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS730882167 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS730882168 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS730882169 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS730882172 |
KCNH1
|
Health Risk |
Pathogenic |
Zimmermann-Laband syndrome 1, Zimmermann-Laband syndrome 1 |
| RS730882173 |
KCNH1
|
Health Risk |
Pathogenic |
Zimmermann-Laband syndrome 1, Zimmermann-Laband syndrome 1 |
| RS730882174 |
KCNH1
|
Health Risk |
Pathogenic |
Zimmermann-Laband syndrome 1, Zimmermann-Laband syndrome 1 |
| RS730882175 |
KCNH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Zimmermann-Laband syndrome 1, Inborn genetic diseases |
| RS730882176 |
KCNH1
|
Health Risk |
Pathogenic |
Zimmermann-Laband syndrome 1, Zimmermann-Laband syndrome 1 |
| RS730882177 |
ATP6V1B2
|
Health Risk |
Pathogenic |
Zimmermann-Laband syndrome 2, Zimmermann-Laband syndrome 1 |
| RS730882178 |
FRAS1
|
Health Risk |
Pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS730882179 |
FRAS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS730882180 |
FRAS1
|
Health Risk |
Pathogenic |
Fraser syndrome 1, Fraser syndrome 1 |
| RS730882181 |
PHGDH
|
Health Risk |
Pathogenic |
PHGDH deficiency, PHGDH deficiency |
| RS730882182 |
RAB3GAP1
|
Health Risk |
Pathogenic |
Warburg micro syndrome 1, Warburg micro syndrome 1 |
| RS730882183 |
RAB3GAP1
|
Health Risk |
Pathogenic |
Warburg micro syndrome 1, Warburg micro syndrome 1 |
| RS730882184 |
RAB3GAP1
|
Health Risk |
Pathogenic |
Warburg micro syndrome 1, Warburg micro syndrome 1 |
| RS730882185 |
BRWD3
|
Health Risk |
Pathogenic |
Intellectual disability, X-linked 93 |
| RS730882186 |
BRWD3
|
Health Risk |
Pathogenic |
Intellectual disability, X-linked 93 |
| RS730882187 |
SLC9A6
|
Health Risk |
Pathogenic |
Christianson syndrome, Christianson syndrome |
| RS730882188 |
SLC9A6
|
Health Risk |
Pathogenic |
Christianson syndrome, Christianson syndrome |
| RS730882189 |
POU3F4
|
Health Risk |
Pathogenic |
X-linked mixed hearing loss with perilymphatic gusher, X-linked mixed hearing loss with perilymphatic gusher |
| RS730882190 |
COL11A1
|
Health Risk |
Pathogenic |
Fibrochondrogenesis, Fibrochondrogenesis |
| RS730882191 |
PITX1
|
Health Risk |
Pathogenic |
Clubfoot, Clubfoot |
| RS730882192 |
MEF2C
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with hypotonia, stereotypic hand movements |
| RS730882193 |
AXIN2
|
Health Risk |
Pathogenic |
Oligodontia-cancer predisposition syndrome, AXIN2-related attenuated familial adenomatous polyposis |
| RS730882194 |
EMP2
|
Health Risk |
Pathogenic |
Nephrotic syndrome, type 10 |
| RS730882195 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-hypotonia-spasticity-sleep disorder syndrome, Intellectual disability-hypotonia-spasticity-sleep disorder syndrome |
| RS730882197 |
FERRY3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypotonia, Intellectual disability |
| RS730882198 |
SPART
|
Health Risk |
Pathogenic |
6 conditions, Troyer syndrome |
| RS730882199 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Regression of motor development with severe dystonia and corresponding basal ganglia lesions, Cholestanol storage disease |
| RS730882200 |
ARFGEF2
|
Health Risk |
Pathogenic |
Global developmental delay, Seizure |
| RS730882201 |
ARL14EP
|
Health Risk |
Likely pathogenic |
Global developmental delay, Abnormal facial shape |
| RS730882202 |
CACNA1G
|
Health Risk |
Likely pathogenic |
Abnormal facial shape, Hirsutism |
| RS730882203 |
DMBX1
|
Health Risk |
Likely pathogenic |
6 conditions, 6 conditions |
| RS730882204 |
WDR93
|
Health Risk |
Likely pathogenic |
Autistic spectrum disorder with isolated skills, Autistic spectrum disorder with isolated skills |
| RS730882205 |
ZNF526
|
Health Risk |
Likely pathogenic |
Pulmonic stenosis, Noonan-like facies |
| RS730882206 |
WDR81
|
Health Risk |
Likely pathogenic |
Hydranencephaly, Neonatal death |
| RS730882207 |
EPB41L4A
|
Health Risk |
Likely pathogenic |
Failure to thrive, Spastic paraplegia |
| RS730882208 |
CTSD
|
Health Risk |
Likely pathogenic |
Severe microlissencephaly, Exaggerated startle response |
| RS730882209 |
SETX
|
Health Risk |
Pathogenic/Likely pathogenic |
7 conditions, Spinocerebellar ataxia |
| RS730882210 |
MATN4
|
Health Risk |
Likely pathogenic |
7 conditions, 7 conditions |
| RS730882212 |
TUBA3E
|
Health Risk |
Likely pathogenic |
Primary microcephaly, Seizure |
| RS730882213 |
ADAT3;SCAMP4
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability-strabismus syndrome, Neurodevelopmental disorder with brain abnormalities |
| RS730882214 |
PLA2G6
|
Health Risk |
Likely pathogenic |
Neurodegeneration with brain iron accumulation, Neurodegeneration with brain iron accumulation |
| RS730882215 |
WWOX
|
Health Risk |
Pathogenic |
Global developmental delay, Brain atrophy |
| RS730882216 |
NUP107
|
Health Risk |
Pathogenic/Likely pathogenic |
Early onset focal segmental glomerulosclerosis, Global developmental delay |
| RS730882217 |
CPLANE1
|
Health Risk |
Pathogenic |
Global developmental delay, Typical Joubert syndrome MRI findings |
| RS730882218 |
MGAT2
|
Health Risk |
Likely pathogenic |
MGAT2-congenital disorder of glycosylation, Abnormal glycosylation |
| RS730882219 |
GEMIN4
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly, Severe dystonia |
| RS730882220 |
FAM20C
|
Health Risk |
Likely pathogenic |
Cortical dysplasia, Neonatal death |
| RS730882221 |
TCTN1
|
Health Risk |
Pathogenic |
Global developmental delay, Typical Joubert syndrome MRI findings |
| RS730882222 |
SLC13A5
|
Health Risk |
Likely pathogenic |
Global developmental delay, Seizure |
| RS730882224 |
PNKP
|
Health Risk |
Likely pathogenic |
Global developmental delay, Primary microcephaly |
| RS730882225 |
NID1
|
Health Risk |
Likely pathogenic |
Focal epilepsy, Hemiparesis |
| RS730882226 |
INO80
|
Health Risk |
Likely pathogenic |
Primary microcephaly, Seizure |
| RS730882228 |
SPDL1
|
Health Risk |
Likely pathogenic |
Neonatal death, Severe primary microcephaly |
| RS730882229 |
PTPN23
|
Health Risk |
Pathogenic/Likely pathogenic |
Global developmental delay, Seizure |
| RS730882230 |
FBN2
|
Health Risk |
Likely pathogenic |
Cerebral ischemia, Fetal akinesia deformation sequence 1 |
| RS730882231 |
TMEM237
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome 14 |
| RS730882233 |
EXOC4
|
Health Risk |
Likely pathogenic |
Meckel-Gruber syndrome, Meckel-Gruber syndrome |
| RS730882234 |
PTRH2
|
Health Risk |
Pathogenic |
Cerebellar ataxia, Global developmental delay |
| RS730882235 |
KLHL41
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 9, Nemaline myopathy |
| RS730882236 |
COG6
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome, Hypohidrosis |
| RS730882237 |
B4GAT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS730882238 |
DOCK6
|
Health Risk |
Pathogenic/Likely pathogenic |
Adams-Oliver syndrome 2, Adams-Oliver syndrome |
| RS730882240 |
PIGQ
|
Health Risk |
Pathogenic |
Optic atrophy, Global developmental delay |
| RS730882241 |
ARV1
|
Health Risk |
Likely pathogenic |
Neurodegeneration, Blindness |
| RS730882242 |
DIAPH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Global developmental delay, Microcephaly |
| RS730882244 |
FAM177A1
|
Health Risk |
Likely pathogenic |
Mild obesity, Dolichocephaly |
| RS730882245 |
BLTP1
|
Health Risk |
Pathogenic |
6 conditions, Alkuraya-Kucinskas syndrome |
| RS730882246 |
ISCA2
|
Health Risk |
Pathogenic/Likely pathogenic |
8 conditions, Multiple mitochondrial dysfunctions syndrome 4 |
| RS730882247 |
TMEM92
|
Health Risk |
Likely pathogenic |
Global developmental delay, Cerebellar atrophy |
| RS730882248 |
RNF216
|
Health Risk |
Likely pathogenic |
Leukodystrophy, Hypogonadotropic hypogonadism 7 with or without anosmia |
| RS730882249 |
AP4M1
|
Health Risk |
Pathogenic |
CNS hypomyelination, Brain atrophy |
| RS730882250 |
DPH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Dandy-Walker syndrome, Global developmental delay |
| RS730882252 |
CALM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Long QT syndrome 14, Long QT syndrome 14 |
| RS730882253 |
CALM1
|
Health Risk |
Likely pathogenic |
Long QT syndrome 14, Long QT syndrome 14 |
| RS730882254 |
CALM2
|
Health Risk |
Pathogenic |
Long QT syndrome 15, Long QT syndrome 1 |
| RS730882255 |
ALS2
|
Health Risk |
Pathogenic |
Amyotrophic lateral sclerosis type 2, juvenile |
| RS730882256 |
ALS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Amyotrophic lateral sclerosis type 2, juvenile |
| RS730882257 |
KLHL41
|
Health Risk |
Pathogenic |
Nemaline myopathy 9, Nemaline myopathy 9 |
| RS730882258 |
KLHL41
|
Health Risk |
Pathogenic |
Nemaline myopathy 9, Nemaline myopathy 9 |
| RS730882259 |
KLHL41
|
Health Risk |
Pathogenic |
Nemaline myopathy 9, Nemaline myopathy 9 |
| RS730882260 |
KLHL41
|
Health Risk |
Pathogenic |
Nemaline myopathy 9, Nemaline myopathy 9 |
| RS730882261 |
RPGR
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinal dystrophy |