ZNF526 Chromosome 19
Zinc finger protein 526
Upload your DNA to see your personal genotypes for variants in ZNF526.
What This Gene Does
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
Zinc fingers C2H2-type
Locus Type
gene with protein product
Location
19q13.2
Ensembl
ENSG00000167625
Associated Conditions (6)
ZNF526-related disorder
Dentici-Novelli neurodevelopmental syndrome
Inborn genetic diseases
Pulmonic stenosis
Noonan-like facies
Intellectual disability
Key Variants
RS138082392
Conflicting classifications of pathogenicity
ZNF526-related disorder, ZNF526-related disorder
Health Risk
RS144433879
Conflicting classifications of pathogenicity
Dentici-Novelli neurodevelopmental syndrome, Inborn genetic diseases, Dentici-Novelli neurodevelopmental syndrome
Health Risk
RS149913848
Conflicting classifications of pathogenicity
Health Risk
RS200018551
Conflicting classifications of pathogenicity
ZNF526-related disorder, ZNF526-related disorder
Health Risk
RS730882205
Likely pathogenic
Pulmonic stenosis, Noonan-like facies, Intellectual disability
Health Risk
RS1201644078
Pathogenic
Dentici-Novelli neurodevelopmental syndrome, Dentici-Novelli neurodevelopmental syndrome
Health Risk
RS2146930042
Pathogenic
Dentici-Novelli neurodevelopmental syndrome, Dentici-Novelli neurodevelopmental syndrome
Health Risk
RS754536246
Pathogenic
Dentici-Novelli neurodevelopmental syndrome, Dentici-Novelli neurodevelopmental syndrome
Health Risk
All Variants (8)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS138082392 | Health Risk | Conflicting classifications of pathogenicity | ZNF526-related disorder, ZNF526-related disorder |
| RS144433879 | Health Risk | Conflicting classifications of pathogenicity | Dentici-Novelli neurodevelopmental syndrome, Inborn genetic diseases, Dentici-Novelli neurodevelopmental syndrome |
| RS149913848 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200018551 | Health Risk | Conflicting classifications of pathogenicity | ZNF526-related disorder, ZNF526-related disorder |
| RS730882205 | Health Risk | Likely pathogenic | Pulmonic stenosis, Noonan-like facies, Intellectual disability |
| RS1201644078 | Health Risk | Pathogenic | Dentici-Novelli neurodevelopmental syndrome, Dentici-Novelli neurodevelopmental syndrome |
| RS2146930042 | Health Risk | Pathogenic | Dentici-Novelli neurodevelopmental syndrome, Dentici-Novelli neurodevelopmental syndrome |
| RS754536246 | Health Risk | Pathogenic | Dentici-Novelli neurodevelopmental syndrome, Dentici-Novelli neurodevelopmental syndrome |