| RS566375223 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS566377861 |
ACOX1
|
Health Risk |
Likely pathogenic |
Muscle weakness, Muscle weakness |
| RS566381009 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS566388572 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS566409623 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome |
| RS566411892 |
HPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS566415362 |
ANO5
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2L, Gnathodiaphyseal dysplasia |
| RS566417795 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS566419089 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Acromicric dysplasia, Ectopia lentis 1 |
| RS566436667 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS566440675 |
ATP6V0A4
|
Health Risk |
Pathogenic |
— |
| RS566448118 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS566450108 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS566453434 |
FBP1
|
Health Risk |
Pathogenic |
Fructose-biphosphatase deficiency, Fructose-biphosphatase deficiency |
| RS566454891 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Myopathy |
| RS566461626 |
MXI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ovarian cancer, Ovarian cancer |
| RS566463138 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Cardiovascular phenotype |
| RS566463967 |
RSPH1
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS566464225 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS566481621 |
ELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Supravalvar aortic stenosis, Supravalvar aortic stenosis |
| RS566485657 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS566490774 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS566495420 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS566506678 |
MYH11
|
Health Risk |
Pathogenic |
Aortic aneurysm, familial thoracic 4 |
| RS566507872 |
SLC4A11
|
Health Risk |
Pathogenic |
— |
| RS566510315 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures, Inborn genetic diseases |
| RS566514527 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS566515249 |
DGAT1
|
Health Risk |
Likely pathogenic |
— |
| RS566516658 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS566518051 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group D2, Fanconi anemia |
| RS566519921 |
TMEM147
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with facial dysmorphism, absent language |
| RS566531015 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS566537432 |
TONSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS566540835 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS566549635 |
GSS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inherited glutathione synthetase deficiency, Inborn genetic diseases |
| RS566562286 |
SRD5A2
|
Health Risk |
Pathogenic |
3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency, 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency |
| RS566562378 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS566563238 |
JAG1
|
Health Risk |
Pathogenic/Likely pathogenic |
Alagille syndrome due to a JAG1 point mutation, Alagille syndrome due to a JAG1 point mutation |
| RS566568065 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS566572599 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures, Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures |
| RS56657623 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiomyopathy |
| RS566579080 |
TWNK
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS56658066 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS566580675 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS566580738 |
HEXA
|
Health Risk |
Pathogenic/Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS566593066 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS566595009 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS566595038 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS566601241 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS566605780 |
ETFDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS566606862 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Autosomal dominant cerebellar ataxia |
| RS566614598 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS566619057 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS566620411 |
MPI
|
Health Risk |
Likely pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS566641514 |
MESP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondylocostal dysostosis 2, autosomal recessive |
| RS566644989 |
CPT1C
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 73, Hereditary spastic paraplegia 73 |
| RS566653064 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS566673314 |
AGRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 8, Inborn genetic diseases |
| RS566674356 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Inborn genetic diseases |
| RS566677129 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Familial cold autoinflammatory syndrome 2 |
| RS566680728 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS566690413 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS566693857 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Werner syndrome |
| RS566695508 |
ICOSLG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS566704910 |
KCNJ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 2, Bartter disease type 2 |
| RS566705895 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS566713386 |
LIG3
|
Health Risk |
Likely pathogenic |
Mitochondrial DNA depletion syndrome 20 (mngie type), Mitochondrial DNA depletion syndrome 20 (mngie type) |
| RS56673169 |
LMNA
|
Health Risk |
Pathogenic |
Mandibuloacral dysplasia with type A lipodystrophy, Mandibuloacral dysplasia with type A lipodystrophy |
| RS566738926 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS566755911 |
DRC4
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 33, GAS8-related disorder |
| RS566764105 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS566790184 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss, Autosomal dominant nonsyndromic hearing loss 17 |
| RS56679084 |
GFAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Alexander disease, Alexander disease |
| RS566794300 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS566806768 |
AMH
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, AMH-related disorder |
| RS566813395 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS566814350 |
SLC52A2
|
Health Risk |
Likely pathogenic |
— |
| RS566816279 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Myopathy |
| RS566827108 |
C2CD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS566837952 |
SLC19A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Biotin-responsive basal ganglia disease, Biotin-responsive basal ganglia disease |
| RS566840716 |
PRSS56
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated microphthalmia 6, Inborn genetic diseases |
| RS566846495 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS566858747 |
SLC52A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Brown-Vialetto-van Laere syndrome 2, Inborn genetic diseases |
| RS566860680 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS566860712 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1AA |
| RS566865273 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS566868058 |
FGF23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypophosphatemic rickets, Tumoral calcinosis |
| RS566876047 |
AMH
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS566876110 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Potassium-aggravated myotonia, Congenital myasthenic syndrome 16 |
| RS566879134 |
BICRA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS566881806 |
ZNF513
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS566882530 |
BMP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Microphthalmia with brain and digit anomalies, Orofacial cleft 11 |
| RS566884215 |
GALE
|
Health Risk |
Conflicting classifications of pathogenicity |
UDPglucose-4-epimerase deficiency, UDPglucose-4-epimerase deficiency |
| RS566885717 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS56690581 |
KRT17
|
Health Risk |
Likely pathogenic |
— |
| RS566911022 |
MNX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS566912235 |
RBCK1
|
Health Risk |
Likely pathogenic |
Polyglucosan body myopathy type 1, Polyglucosan body myopathy 1 without immunodeficiency |
| RS566913021 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Loeys-Dietz syndrome 2, Loeys-Dietz syndrome 2 |
| RS566914013 |
SFTPC
|
Health Risk |
Conflicting classifications of pathogenicity |
Surfactant metabolism dysfunction, pulmonary |
| RS566917467 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |