| RS564856283 |
MYBPC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Myopathy, congenital |
| RS564858245 |
DHFR;MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, MSH3-related disorder |
| RS564867814 |
PIEZO2
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO2-related disorder, Inborn genetic diseases |
| RS564869863 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS564871157 |
GABRA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, idiopathic generalized |
| RS564875531 |
UNC13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 3, Autoinflammatory syndrome |
| RS564880597 |
CSF3R
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive severe congenital neutropenia due to CSF3R deficiency, Inborn genetic diseases |
| RS564884307 |
IL12RB1
|
Health Risk |
Pathogenic |
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency, Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency |
| RS564887323 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Elliptocytosis 2, Hereditary spherocytosis type 3 |
| RS564894886 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, TNXB-related disorder |
| RS564897812 |
ADCY10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS564899884 |
MYO1E
|
Health Risk |
Conflicting classifications of pathogenicity |
MYO1E-related disorder, Focal segmental glomerulosclerosis 6 |
| RS564908429 |
ABCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCC2-related disorder, ABCC2-related disorder |
| RS564910868 |
CD46
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome, Atypical hemolytic-uremic syndrome |
| RS564911507 |
CIC
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Intellectual disability |
| RS564917505 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, arthrochalasia type |
| RS564919438 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS564929531 |
SLC5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Familial renal glucosuria |
| RS564930066 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS564930869 |
CHRND
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal multiple pterygium syndrome, Inborn genetic diseases |
| RS564937293 |
CACNA1D
|
Health Risk |
Conflicting classifications of pathogenicity |
Sinoatrial node dysfunction and deafness, Sinoatrial node dysfunction and deafness |
| RS564938323 |
NSUN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 5 |
| RS564939247 |
ARMC9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS564943632 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS564949885 |
TH
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive DOPA responsive dystonia, Inborn genetic diseases |
| RS564964646 |
C5
|
Health Risk |
Conflicting classifications of pathogenicity |
Complement component 5 deficiency, Complement component 5 deficiency |
| RS564977715 |
TPM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arthrogryposis, distal |
| RS564979861 |
HGD
|
Health Risk |
Pathogenic/Likely pathogenic |
Alkaptonuria, Alkaptonuria |
| RS564992297 |
RPGRIP1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS565004625 |
RNF213
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS565012397 |
OPA3
|
Health Risk |
Conflicting classifications of pathogenicity |
3-Methylglutaconic aciduria type 3, Optic atrophy 3 |
| RS565013143 |
ALDOA
|
Health Risk |
Conflicting classifications of pathogenicity |
HNSHA due to aldolase A deficiency, ALDOA-related disorder |
| RS565013600 |
SYNJ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-onset Parkinson disease 20 |
| RS565020131 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS565025643 |
KCNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 26 |
| RS565042425 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS565046666 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 25, Retinitis pigmentosa 25 |
| RS565049190 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 1A (Zellweger), Zellweger spectrum disorders |
| RS565049855 |
DIS3L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Perlman syndrome, Perlman syndrome |
| RS565065320 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS565069721 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Sarcoglycanopathy |
| RS565073445 |
BBS12
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 12 |
| RS565076112 |
DNAH5
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS565082329 |
TSHR
|
Health Risk |
Likely pathogenic |
Hypothyroidism due to TSH receptor mutations, Hypothyroidism due to TSH receptor mutations |
| RS565088728 |
ITGA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa with pyloric atresia, Epidermolysis bullosa |
| RS565089874 |
FLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS565090080 |
ECHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency, Inborn genetic diseases |
| RS565091566 |
TARDBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 10, FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS |
| RS565096713 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS565096937 |
FIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Amyotrophic lateral sclerosis type 11 |
| RS565098856 |
PHIP
|
Health Risk |
Pathogenic |
Early onset severe obesity, Early onset severe obesity |
| RS565100245 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS565102282 |
YARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, lactic acidosis |
| RS565110158 |
ASXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Shashi-Pena syndrome, Intellectual disability |
| RS565132015 |
LRBA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to LRBA deficiency, Inborn genetic diseases |
| RS565136635 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 11, Cardiomyopathy |
| RS565137573 |
SPEG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS565152814 |
RPGRIP1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS565156541 |
AUTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS565162134 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1B, MYO7A-related disorder |
| RS565173276 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS565184120 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS565203731 |
SACS
|
Health Risk |
Pathogenic/Likely pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS565206764 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS565210312 |
PDYN
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 23, Spinocerebellar ataxia type 23 |
| RS565211544 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS565214018 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS565216093 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS565216977 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS565224393 |
NARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation defect type 24, Combined oxidative phosphorylation defect type 24 |
| RS565227443 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS565229873 |
LAMB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pierson syndrome, LAMB2-related infantile-onset nephrotic syndrome |
| RS565236615 |
LRMDA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS565236668 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS565238806 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS565241553 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS565245995 |
LRP5
|
Health Risk |
Conflicting classifications of pathogenicity |
8 conditions, 8 conditions |
| RS565253666 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Abnormality of the nervous system |
| RS565256491 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Polycystic kidney disease |
| RS565261873 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS565262730 |
ACVRL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Telangiectasia, hereditary hemorrhagic |
| RS565266663 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS565268514 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS565270893 |
ABHD12
|
Health Risk |
Conflicting classifications of pathogenicity |
ABHD12-related disorder, ABHD12-related disorder |
| RS565283604 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS565287436 |
KCNE3
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 6, Cardiovascular phenotype |
| RS565288028 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Arrhythmogenic right ventricular dysplasia 2 |
| RS565288775 |
LBR
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Malignant tumor of urinary bladder |
| RS565291398 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2Q, Epidermolysis bullosa simplex with nail dystrophy |
| RS565294723 |
BOLA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple mitochondrial dysfunctions syndrome 2, Multiple mitochondrial dysfunctions syndrome 2 |
| RS565299079 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS565307908 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, PIEZO1-related disorder |
| RS565314634 |
INS
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal insulin-dependent diabetes mellitus, Neonatal insulin-dependent diabetes mellitus |
| RS565316605 |
SMARCAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schimke immuno-osseous dysplasia, Inborn genetic diseases |
| RS565318742 |
ACAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS565329216 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS565333965 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS565336088 |
IMPG1
|
Health Risk |
Pathogenic |
— |
| RS565345523 |
IL12B
|
Health Risk |
Conflicting classifications of pathogenicity |
Mendelian susceptibility to mycobacterial diseases due to complete IL12B deficiency, Inborn genetic diseases |
| RS565348836 |
MMUT
|
Health Risk |
Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to complete methylmalonyl-CoA mutase deficiency |