| RS564296987 |
TPM3
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy 4B, autosomal recessive |
| RS564306903 |
L2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
L-2-hydroxyglutaric aciduria, L-2-hydroxyglutaric aciduria |
| RS564308785 |
LAMA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa gravis of Herlitz, Laryngo-onycho-cutaneous syndrome |
| RS564309046 |
SHPK
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS564314108 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS564316199 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS564331848 |
FOLR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral folate transport deficiency, Inborn genetic diseases |
| RS564334744 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS564339518 |
SOX9
|
Health Risk |
Conflicting classifications of pathogenicity |
Camptomelic dysplasia, Camptomelic dysplasia |
| RS564352128 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS564353179 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS564358410 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Hypertrophic cardiomyopathy |
| RS564362618 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Cohen syndrome |
| RS564367705 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy 14 |
| RS564395221 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Lymphatic malformation 6, Inborn genetic diseases |
| RS564398642 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS564400636 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS564401238 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS564403550 |
ELMOD3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS564403641 |
SRD5A2
|
Health Risk |
Likely pathogenic |
— |
| RS564408927 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Juvenile polyposis syndrome |
| RS564412855 |
BBS5
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 5 |
| RS564413149 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Cataract 41, Autosomal dominant nonsyndromic hearing loss 6 |
| RS564413710 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS564421091 |
COL9A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS564427867 |
PCSK9
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS564428355 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-IV-B |
| RS564432498 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS564434147 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS564438778 |
CLIC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 103, CLIC5-related disorder |
| RS564439710 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS564448342 |
ANKRD26
|
Health Risk |
Conflicting classifications of pathogenicity |
ANKRD26-related disorder, ANKRD26-related disorder |
| RS564452430 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral arteriopathy, autosomal dominant |
| RS564464466 |
GABRG2
|
Health Risk |
Pathogenic |
EPILEPSY, CHILDHOOD ABSENCE |
| RS564470096 |
FAT2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS564473574 |
PTPRO
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 6 |
| RS564477999 |
TBC1D24
|
Health Risk |
Likely pathogenic |
Rolandic epilepsy-paroxysmal exercise-induced dystonia-writer's cramp syndrome, TBC1D24-related disorder |
| RS564494780 |
SOX11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS564495912 |
RYR1
|
Health Risk |
Likely pathogenic |
RYR1-related disorder, Malignant hyperthermia |
| RS564496088 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hereditary spastic paraplegia 39 |
| RS564501639 |
SPR
|
Health Risk |
Conflicting classifications of pathogenicity |
Dopa-responsive dystonia due to sepiapterin reductase deficiency, Inborn genetic diseases |
| RS564504598 |
CCDC40
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS564510830 |
MED12L
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Inborn genetic diseases |
| RS564514095 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS564526560 |
GALC
|
Health Risk |
Conflicting classifications of pathogenicity |
Galactosylceramide beta-galactosidase deficiency, GALC-related disorder |
| RS564532190 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS564532686 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, CHRNA2-related disorder |
| RS564553038 |
PDGFB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS564554926 |
DOCK6
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, Inborn genetic diseases |
| RS564570407 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant polycystic kidney disease, Autosomal dominant polycystic kidney disease |
| RS564570566 |
SCNN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Liddle syndrome 1, Pseudohypoaldosteronism |
| RS564582352 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 1 |
| RS564588440 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS564593360 |
COQ8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS564595203 |
OTOG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS564605452 |
NPHP1
|
Health Risk |
Likely pathogenic |
Joubert syndrome and related disorders, Joubert syndrome with renal defect |
| RS564605612 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS564606657 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS564622720 |
MYO7A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 2, Usher syndrome type 1 |
| RS564628353 |
FLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS564631426 |
NPC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Niemann-Pick disease |
| RS564632018 |
FKTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Cardiovascular phenotype |
| RS564632841 |
LHCGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Leydig cell agenesis, Gonadotropin-independent familial sexual precocity |
| RS564637804 |
CUBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Imerslund-Grasbeck syndrome, Imerslund-Grasbeck syndrome type 1 |
| RS564645287 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive distal spinal muscular atrophy 1 |
| RS564645548 |
MYO7A
|
Health Risk |
Pathogenic |
— |
| RS564647544 |
SCARB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Inborn genetic diseases |
| RS564647937 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS564652222 |
ATM
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS564657106 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS564667614 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial focal |
| RS564668486 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 7, Familial episodic pain syndrome with predominantly lower limb involvement |
| RS564681878 |
ANKRD26
|
Health Risk |
Conflicting classifications of pathogenicity |
ANKRD26-related disorder, ANKRD26-related disorder |
| RS564687150 |
CENPF
|
Health Risk |
Likely pathogenic |
— |
| RS564701277 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, DYNC2H1-related disorder |
| RS564705275 |
YIF1B
|
Health Risk |
Pathogenic |
Kaya-Barakat-Masson syndrome, Kaya-Barakat-Masson syndrome |
| RS564713154 |
FBN1
|
Health Risk |
Pathogenic |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS564717613 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS564728455 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS564735357 |
ASL
|
Health Risk |
Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS564736113 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS564740435 |
FREM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated cryptophthalmia, Fraser syndrome 2 |
| RS564752140 |
GUCA1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS564754426 |
CRB1
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Stargardt disease |
| RS564759063 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS564764153 |
ABCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS564765063 |
MPI
|
Health Risk |
Conflicting classifications of pathogenicity |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS564767670 |
PLCG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation, Familial cold autoinflammatory syndrome 3 |
| RS564784943 |
MAN1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rafiq syndrome, Inborn genetic diseases |
| RS564786398 |
ADGRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS564787975 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Developmental and epileptic encephalopathy 94 |
| RS564795973 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glomerulopathy with fibronectin deposits 2, Spondylometaphyseal dysplasia - Sutcliffe type |
| RS564799796 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant cerebellar ataxia, Autosomal dominant cerebellar ataxia |
| RS564806219 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS564811653 |
KIF12
|
Health Risk |
Likely pathogenic |
Cholestasis, progressive familial intrahepatic |
| RS564812596 |
GGCX
|
Health Risk |
Pathogenic |
GGCX-related disorder, GGCX-related disorder |
| RS564822776 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS564822781 |
LPIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoglobinuria, acute recurrent |
| RS564847999 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiac arrhythmia |
| RS564855597 |
OBSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |