| RS563142074 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebrooculofacioskeletal syndrome 1, Cockayne syndrome type 2 |
| RS563144239 |
LARGE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy type B6, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS563145604 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS563149622 |
ABCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tangier disease, Hypoalphalipoproteinemia |
| RS563151154 |
LDLRAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS56315337 |
TEX14
|
Health Risk |
Pathogenic |
Non-obstructive azoospermia, Non-obstructive azoospermia |
| RS563156233 |
DOLK
|
Health Risk |
Conflicting classifications of pathogenicity |
DK1-congenital disorder of glycosylation, Cardiovascular phenotype |
| RS563163157 |
COCH
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 9, Autosomal dominant nonsyndromic hearing loss 9 |
| RS563171274 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS56317927 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BRCA2-related disorder |
| RS563189672 |
MRPS34
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation deficiency 32, Ovarian serous cystadenocarcinoma |
| RS563194186 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Cardiovascular phenotype |
| RS563202944 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
ZNF469-related disorder, Cardiovascular phenotype |
| RS563208176 |
GUCY2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Cone-rod dystrophy 6 |
| RS56321129 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS563222200 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Rapadilino syndrome |
| RS563225941 |
FLII
|
Health Risk |
Likely pathogenic |
Primary dilated cardiomyopathy, Cardiomyopathy |
| RS563228953 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Congenital contractural arachnodactyly |
| RS563231684 |
RIT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 8, Noonan syndrome and Noonan-related syndrome |
| RS563232654 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Tetralogy of Fallot |
| RS563233842 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1G |
| RS563236303 |
XPC
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group C |
| RS563237107 |
HRG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS563238934 |
DYRK1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Abdominal obesity-metabolic syndrome 3, DYRK1B-related disorder |
| RS563239 |
KMT2A
|
Health Risk |
Pathogenic |
— |
| RS563241317 |
GBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type IV |
| RS563241895 |
CP
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of ferroxidase, Inborn genetic diseases |
| RS563243550 |
PHIP
|
Health Risk |
Conflicting classifications of pathogenicity |
PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome, Inborn genetic diseases |
| RS563246146 |
CYP11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Corticosterone methyloxidase type 2 deficiency, Glucocorticoid-remediable aldosteronism |
| RS56324666 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS56325023 |
MBL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mannose-binding lectin deficiency, Mannose-binding lectin deficiency |
| RS563259179 |
LRSAM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2P, Charcot-Marie-Tooth disease |
| RS563259198 |
ALG12
|
Health Risk |
Pathogenic |
ALG12-congenital disorder of glycosylation, ALG12-congenital disorder of glycosylation |
| RS563275093 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal recessive form |
| RS563275223 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS56327920 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, MYH9-related disorder |
| RS563280837 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, DNAH11-related disorder |
| RS56328701 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast neoplasm, Hereditary cancer-predisposing syndrome |
| RS563288128 |
NBAS
|
Health Risk |
Pathogenic |
— |
| RS56329598 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS563296138 |
NTRK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary insensitivity to pain with anhidrosis, Inborn genetic diseases |
| RS56329631 |
IKBKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to IKK2 deficiency, Severe combined immunodeficiency due to IKK2 deficiency |
| RS56329646 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS563299553 |
SARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperuricemia, pulmonary hypertension |
| RS56330345 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS563304627 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS563304664 |
CPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital hyperammonemia, type I |
| RS563305936 |
TGM1
|
Health Risk |
Pathogenic |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS56331088 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS563315271 |
RUSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 61 |
| RS563317319 |
ST3GAL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS56332208 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 9, Malignant tumor of esophagus |
| RS563322370 |
TMC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal dominant nonsyndromic hearing loss 36, Autosomal recessive nonsyndromic hearing loss 7 |
| RS563324563 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS563328673 |
RTTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS563331592 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS563333401 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Sick sinus syndrome 2, autosomal dominant |
| RS563333869 |
ATP6V0A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa with osteodystrophy, ALG9 congenital disorder of glycosylation |
| RS563335203 |
CA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS563335387 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS56333627 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS563338043 |
MYOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Angioedema, hereditary |
| RS563342580 |
CASQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 2, Catecholaminergic polymorphic ventricular tachycardia 2 |
| RS563345134 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS563345694 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS563345848 |
PHKB
|
Health Risk |
Pathogenic |
Glycogen storage disease IXb, Glycogen phosphorylase kinase deficiency |
| RS563352149 |
RSPH4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 11, Primary ciliary dyskinesia |
| RS56335342 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 3, Maturity-onset diabetes of the young |
| RS56335406 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS563356062 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS563358516 |
SORL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS563360548 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHD7-related disorder |
| RS56336919 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS563376014 |
ATP5F1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS563376340 |
SLC2A10
|
Health Risk |
Conflicting classifications of pathogenicity |
Arterial tortuosity syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS563377054 |
DGAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS563377499 |
OBSCN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS563378859 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS563382903 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
FLNB-Related Spectrum Disorders, FLNB-Related Spectrum Disorders |
| RS56338790 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS563390335 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS56339365 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy 4 |
| RS563393715 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Cardiovascular phenotype |
| RS56339482 |
CYP1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glaucoma 3A, Irido-corneo-trabecular dysgenesis |
| RS563400584 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS563401372 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Ehlers-Danlos syndrome |
| RS563403703 |
NPHP3
|
Health Risk |
Conflicting classifications of pathogenicity |
NPHP3-related Meckel-like syndrome, Renal-hepatic-pancreatic dysplasia 1 |
| RS563410947 |
MSH2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS56341125 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, RECQL4-related disorder |
| RS563415711 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa 41 |
| RS563417983 |
PCCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Propionic acidemia, PCCA-related disorder |
| RS56341835 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Early-onset myopathy with fatal cardiomyopathy |
| RS563421722 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spinocerebellar ataxia |
| RS56342240 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS563423438 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myotonia, autosomal recessive form |
| RS563430855 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS563433235 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS563440658 |
LAMA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Laryngo-onycho-cutaneous syndrome, Junctional epidermolysis bullosa gravis of Herlitz |
| RS563441026 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive retinitis pigmentosa, Inborn genetic diseases |
| RS563444562 |
LAMC3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |