RS564427867 PCSK9

Health Risk Chr 1:55039931
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What This Variant Does
"CLNSIG=4
Associated Conditions
Hypercholesterolemia
familial
1
Familial hypercholesterolemia
Homozygous familial hypercholesterolemia
autosomal dominant
3
Cardiovascular phenotype
PCSK9-related disorder
Hypercholesterolemia
familial
1
Familial hypercholesterolemia
Homozygous familial hypercholesterolemia
autosomal dominant
GWAS Studies (3)
Trait Risk Allele OR / Beta P-value Study
LDL cholesterol A OR: 0.43 4E-70 PubMed
Medication use (HMG CoA reductase inhibitors) A OR: 0.77 3E-51 PubMed
Coronary artery disease — OR: 0.27 3E-8 PubMed
Other Variants in PCSK9
rs28942111 rs28942112 rs137852912 rs67608943 rs28362286 rs793888521 rs794728683 rs141502002 rs374603772 rs41297883
Ask Dr. Hemsworth about this variant