| RS767744034 |
CUBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Imerslund-Grasbeck syndrome type 1, Proteinuria |
| RS767745136 |
CACNA1E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767745816 |
SPATA7
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Autosomal recessive retinitis pigmentosa |
| RS767745850 |
DOK7
|
Health Risk |
Likely pathogenic |
Fetal akinesia deformation sequence 3, Fetal akinesia deformation sequence 3 |
| RS767747027 |
TBCD
|
Health Risk |
Pathogenic |
— |
| RS767747355 |
ERCC2
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group D |
| RS767747378 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS767747402 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS767748011 |
VPS33A
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis-plus syndrome, Mucopolysaccharidosis-plus syndrome |
| RS767748655 |
AARS2
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 8, Combined oxidative phosphorylation defect type 8 |
| RS767748856 |
CEP78
|
Health Risk |
Pathogenic |
— |
| RS767748953 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS767749967 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis syndrome |
| RS767750936 |
CD55
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767751416 |
ALDH3A2
|
Health Risk |
Pathogenic |
Sjögren-Larsson syndrome, Sjögren-Larsson syndrome |
| RS767751622 |
ARSA
|
Health Risk |
Conflicting classifications of pathogenicity |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS767751856 |
WDR35
|
Health Risk |
Pathogenic |
Cranioectodermal dysplasia 2, Short-rib thoracic dysplasia 7 with or without polydactyly |
| RS767752968 |
CYP19A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767753048 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, seizures |
| RS767753360 |
PKHD1L1
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 124, Autosomal recessive nonsyndromic hearing loss 124 |
| RS767754823 |
ABCC2
|
Health Risk |
Pathogenic |
Dubin-Johnson syndrome, Dubin-Johnson syndrome |
| RS767755367 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS767755750 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS767756650 |
ALDH7A1
|
Health Risk |
Pathogenic |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS767757297 |
POT1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS767757416 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS767758073 |
DNAAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 10, Primary ciliary dyskinesia |
| RS767758218 |
DCLRE1C
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe combined immunodeficiency due to DCLRE1C deficiency, Histiocytic medullary reticulosis |
| RS767758713 |
SEPTIN9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767759337 |
TNFRSF13C
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS767760099 |
DBT
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 1A |
| RS767760664 |
LINS1
|
Health Risk |
Likely pathogenic |
— |
| RS767760877 |
CFAP300
|
Health Risk |
Pathogenic |
Ciliary dyskinesia, primary |
| RS767762611 |
ALS2
|
Health Risk |
Likely pathogenic |
ALS2-related disorder, ALS2-related disorder |
| RS767763451 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Hereditary cancer-predisposing syndrome |
| RS767765046 |
HSD17B3
|
Health Risk |
Pathogenic |
— |
| RS767765131 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS767765146 |
ASB10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767766166 |
TCN1
|
Health Risk |
Pathogenic |
Transcobalamin I deficiency, Transcobalamin I deficiency |
| RS767767037 |
DYM
|
Health Risk |
Pathogenic |
Dyggve-Melchior-Clausen syndrome, Dyggve-Melchior-Clausen syndrome |
| RS767767470 |
PROS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombophilia due to protein S deficiency, autosomal dominant |
| RS767767573 |
USH1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 18A, Usher syndrome type 1C |
| RS767767730 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS767768253 |
BUB1B
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS767768313 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Early-onset myopathy with fatal cardiomyopathy |
| RS767768982 |
MAN2B1
|
Health Risk |
Pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS767769233 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS767769359 |
PRUNE1
|
Health Risk |
Pathogenic/Likely pathogenic |
Abnormal brain morphology, Neurodevelopmental disorder with microcephaly |
| RS767770242 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS767771299 |
ROGDI
|
Health Risk |
Conflicting classifications of pathogenicity |
Amelocerebrohypohidrotic syndrome, Amelocerebrohypohidrotic syndrome |
| RS767772613 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS767772838 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy |
| RS767773802 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767774362 |
ACADS
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of butyryl-CoA dehydrogenase, Deficiency of butyryl-CoA dehydrogenase |
| RS767774622 |
KCNV2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone dystrophy with supernormal rod response, Cone dystrophy with supernormal rod response |
| RS767774867 |
PGAP1
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 42 |
| RS767775507 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 5, Spinocerebellar ataxia type 5 |
| RS767776322 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767777113 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, RYR1-related disorder |
| RS767777964 |
AP3D1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767778853 |
NAXD
|
Health Risk |
Conflicting classifications of pathogenicity |
NAD(P)HX dehydratase deficiency, See cases |
| RS767779208 |
CYP4V2
|
Health Risk |
Pathogenic/Likely pathogenic |
Bietti crystalline corneoretinal dystrophy, Retinal dystrophy |
| RS767779749 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS767780913 |
SERAC1
|
Health Risk |
Pathogenic |
3-methylglutaconic aciduria with deafness, encephalopathy |
| RS767781351 |
VARS2
|
Health Risk |
Likely pathogenic |
— |
| RS767782097 |
POLRMT
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation deficiency 55, Combined oxidative phosphorylation deficiency 55 |
| RS767782156 |
CEP135
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS767782379 |
IVD
|
Health Risk |
Pathogenic |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS767782524 |
RASA2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767782578 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS76778263 |
ICOS
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS767783281 |
CC2D2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS767784355 |
LAMA2
|
Health Risk |
Likely pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS767785738 |
RARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RARS2-related disorder |
| RS767785877 |
PIGQ
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, Developmental and epileptic encephalopathy |
| RS767786513 |
OTOA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767787348 |
MRE11
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS767787371 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant cerebellar ataxia, Spinocerebellar ataxia type 15/16 |
| RS767787774 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS767788330 |
WDR35
|
Health Risk |
Pathogenic/Likely pathogenic |
Cranioectodermal dysplasia 2, Short-rib thoracic dysplasia 7 with or without polydactyly |
| RS767788624 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS767789270 |
MTHFR
|
Health Risk |
Pathogenic |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, Homocystinuria due to methylene tetrahydrofolate reductase deficiency |
| RS767790003 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS767790285 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS767790289 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS767790696 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS767790909 |
GALK1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of galactokinase, Deficiency of galactokinase |
| RS767792289 |
NEXN
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Dilated cardiomyopathy 1CC |
| RS767792503 |
CEP85L
|
Health Risk |
Likely pathogenic |
Lissencephaly 10, Lissencephaly 10 |
| RS767792734 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Basal cell carcinoma |
| RS767793133 |
PRPF6
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS767794176 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS767794768 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 5, Cardiovascular phenotype |
| RS767795266 |
ETFDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS767795583 |
ABCD4
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic acidemia with homocystinuria, type cblJ |
| RS767795673 |
PLPBP
|
Health Risk |
Pathogenic |
Epilepsy, early-onset |
| RS767796290 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Genitopatellar syndrome |
| RS767796996 |
RAD51C
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS767797497 |
LAMA2
|
Health Risk |
Pathogenic |
— |
| RS767797828 |
USH2A
|
Health Risk |
Pathogenic |
Deafness, Hearing loss |