| RS761931104 |
NECTIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cleft lip/palate-ectodermal dysplasia syndrome, Cleft lip/palate-ectodermal dysplasia syndrome |
| RS761931995 |
PLOD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761932822 |
SLC26A2
|
Health Risk |
Pathogenic |
Multiple epiphyseal dysplasia type 4, Diastrophic dysplasia |
| RS761932920 |
TOE1
|
Health Risk |
Likely pathogenic |
Pontocerebellar hypoplasia type 7, Pontocerebellar hypoplasia type 7 |
| RS761934676 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonus, Tremor |
| RS761934754 |
DNMT3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Tatton-Brown-Rahman overgrowth syndrome |
| RS761934778 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS761934962 |
FREM2
|
Health Risk |
Pathogenic |
— |
| RS761935210 |
PTH1R
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761935462 |
CAPN3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS761936549 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Familial cancer of breast |
| RS761937276 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, Adenylosuccinate lyase deficiency |
| RS761937596 |
NSUN2
|
Health Risk |
Likely pathogenic |
— |
| RS761937821 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS761937892 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS761939786 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS761940462 |
FAM161A
|
Health Risk |
Pathogenic |
— |
| RS761941770 |
CDH3
|
Health Risk |
Pathogenic |
Congenital hypotrichosis with juvenile macular dystrophy, Congenital hypotrichosis with juvenile macular dystrophy |
| RS761942436 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS761943372 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761943871 |
MAT1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hepatic methionine adenosyltransferase deficiency, Hepatic methionine adenosyltransferase deficiency |
| RS761944491 |
CHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761944958 |
CPT1A
|
Health Risk |
Likely pathogenic |
Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 1A deficiency |
| RS761945003 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS76194641 |
SACS
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS761946846 |
CASK
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761947194 |
RAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS761947230 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 10, Cardiomyopathy |
| RS761947277 |
CNGA1
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS761947899 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperkalemic periodic paralysis, Hyperkalemic periodic paralysis |
| RS761948522 |
MRTFA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761949902 |
ANO5
|
Health Risk |
Conflicting classifications of pathogenicity |
ANO5-Related Muscle Diseases, Autosomal recessive limb-girdle muscular dystrophy type 2L |
| RS761950154 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS761951444 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS761952496 |
ITGB4
|
Health Risk |
Pathogenic/Likely pathogenic |
Junctional epidermolysis bullosa with pyloric atresia, Epidermolysis bullosa |
| RS761952835 |
TBX5
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic valve disease 2, Cardiovascular phenotype |
| RS761952957 |
NPC1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type C1 |
| RS761953142 |
TNNT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy 2 |
| RS761953453 |
AIFM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukodystrophy, Spondyloepimetaphyseal dysplasia |
| RS761954322 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS761954844 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS761955039 |
FUS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761955179 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS761956085 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS761956614 |
PLA2G6
|
Health Risk |
Pathogenic |
PLA2G6-associated neurodegeneration, PLA2G6-associated neurodegeneration |
| RS761956866 |
SDHAF2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary pheochromocytoma and paraganglioma, Pheochromocytoma/paraganglioma syndrome 2 |
| RS761956867 |
LZTR1
|
Health Risk |
Pathogenic/Likely pathogenic |
LZTR1-related schwannomatosis, LZTR1-related schwannomatosis |
| RS761957186 |
SLC19A2
|
Health Risk |
Pathogenic |
Megaloblastic anemia, thiamine-responsive |
| RS761957607 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS761957837 |
GLDC
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS761958762 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS761959231 |
MED17
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly |
| RS761960429 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761960627 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761960690 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS761960824 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS761961392 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS761962371 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761962752 |
GDF5
|
Health Risk |
Pathogenic |
Grebe syndrome, Grebe syndrome |
| RS761962890 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS761963387 |
UBIAD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schnyder crystalline corneal dystrophy, Schnyder crystalline corneal dystrophy |
| RS761964111 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761964238 |
MMAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblA type |
| RS761964375 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS761964407 |
SERAC1
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylglutaconic aciduria with deafness, encephalopathy |
| RS761965591 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS761965693 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS761966966 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Brugada syndrome 3 |
| RS761967383 |
NTRK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS761967944 |
ELAC2
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation defect type 17, Combined oxidative phosphorylation defect type 17 |
| RS761968225 |
CDC73
|
Health Risk |
Conflicting classifications of pathogenicity |
Parathyroid carcinoma, Hereditary cancer-predisposing syndrome |
| RS761969118 |
CNGB3
|
Health Risk |
Pathogenic/Likely pathogenic |
CNGB3-related disorder, Retinal dystrophy |
| RS761969307 |
MFSD8
|
Health Risk |
Likely pathogenic |
Neuronal ceroid lipofuscinosis 7, Thyroid cancer |
| RS761969357 |
BBS1
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 1 |
| RS761969701 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS761970395 |
EPM2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Progressive myoclonic epilepsy |
| RS761971524 |
MPEG1
|
Health Risk |
Pathogenic |
Immunodeficiency 77, Immunodeficiency 77 |
| RS761971773 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS761972717 |
SH3TC2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease |
| RS761974755 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS761974767 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS761974928 |
FBXL4
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS761975620 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761975891 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS761976262 |
P4HB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cole-Carpenter syndrome 1, Inborn genetic diseases |
| RS761977604 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS761977883 |
ARSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Chondrodysplasia punctata, brachytelephalangic |
| RS761978351 |
XPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum group A, Xeroderma pigmentosum group A |
| RS761978559 |
FLNC
|
Health Risk |
Pathogenic |
Distal myopathy with posterior leg and anterior hand involvement, Hypertrophic cardiomyopathy 26 |
| RS761978806 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS761979060 |
DVL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS761979292 |
TRIM37
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Mulibrey nanism syndrome |
| RS761979645 |
DNAH8
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS761981554 |
SPATA7
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 3, Retinal dystrophy |
| RS761981660 |
KDM6B
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities, Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities |
| RS761982169 |
DNAJC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Inborn genetic diseases |
| RS761982475 |
MC4R
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS761982725 |
FANCI
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group I |
| RS761985420 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS761988162 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |