| RS762051422 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Distal myopathy with posterior leg and anterior hand involvement |
| RS762052051 |
IMPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS762052702 |
RAPSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Fetal akinesia deformation sequence 1, Congenital myasthenic syndrome 11 |
| RS762053925 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS762054841 |
RAG2
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS762055707 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762055797 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 11, Cardiomyopathy |
| RS762056074 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS762058420 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Complement component 3 deficiency, Atypical hemolytic-uremic syndrome with C3 anomaly |
| RS762059806 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS762060470 |
HEXA
|
Health Risk |
Pathogenic/Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS762060755 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS762060817 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS762061869 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS762062043 |
ERBB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Visceral neuropathy, familial |
| RS762062274 |
SLC13A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 25 |
| RS762062705 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Noonan syndrome and Noonan-related syndrome |
| RS762065361 |
CBS
|
Health Risk |
Conflicting classifications of pathogenicity |
HYPERHOMOCYSTEINEMIA, THROMBOTIC |
| RS762065822 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS762065937 |
ABCA12
|
Health Risk |
Likely pathogenic |
Lamellar ichthyosis, Lamellar ichthyosis |
| RS762066700 |
AP5Z1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia |
| RS762066977 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762067222 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS762067290 |
REV3L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762067626 |
MESP2
|
Health Risk |
Likely pathogenic |
Spondylocostal dysostosis 2, autosomal recessive |
| RS762067787 |
SLC25A38
|
Health Risk |
Pathogenic |
Sideroblastic anemia 2, Sideroblastic anemia 2 |
| RS762069191 |
AUTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autism spectrum disorder due to AUTS2 deficiency, Inborn genetic diseases |
| RS762069628 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiomyopathy |
| RS762069884 |
PCDH19
|
Health Risk |
Pathogenic |
Seizure, Seizure |
| RS762070900 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 39 |
| RS762071902 |
TNFRSF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to OX40 deficiency, Combined immunodeficiency due to OX40 deficiency |
| RS762071973 |
GDF5
|
Health Risk |
Pathogenic |
— |
| RS762072069 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS762072595 |
SALL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Townes syndrome, Townes-Brocks syndrome 1 |
| RS762073383 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, RYR1-related disorder |
| RS762073822 |
EXT2
|
Health Risk |
Pathogenic |
— |
| RS762074022 |
ZFP57
|
Health Risk |
Likely pathogenic |
ZFP57-related disorder, Diabetes mellitus |
| RS762075088 |
WFS1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS762076975 |
ALPK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762077987 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762078094 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, LYST-related disorder |
| RS762078182 |
PROM1
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS762078299 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS762079110 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS762079123 |
CLN8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis |
| RS762080553 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS762081081 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS762081490 |
DNAAF11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 19, Primary ciliary dyskinesia 19 |
| RS762081862 |
KIAA0586
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 14 with polydactyly, Joubert syndrome 23 |
| RS762082451 |
KCNV2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone dystrophy with supernormal rod response, Cone dystrophy with supernormal rod response |
| RS762082964 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS762083094 |
COQ4
|
Health Risk |
Likely pathogenic |
Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome, Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome |
| RS762083530 |
ATM
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS762084007 |
BCKDHA
|
Health Risk |
Pathogenic/Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 1A |
| RS762084565 |
COL7A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Epidermolysis bullosa dystrophica, Recessive dystrophic epidermolysis bullosa |
| RS762085901 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica inversa, autosomal recessive |
| RS762087308 |
SLC25A10
|
Health Risk |
Likely pathogenic |
See cases, See cases |
| RS762087385 |
FAM161A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 28, Retinitis pigmentosa |
| RS762088543 |
RHOBTB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762088627 |
MYO3A
|
Health Risk |
Pathogenic |
— |
| RS762088983 |
SPTA1
|
Health Risk |
Pathogenic |
Hereditary spherocytosis type 3, Hereditary spherocytosis type 3 |
| RS762089284 |
PHKG2
|
Health Risk |
Likely pathogenic |
Glycogen storage disease IXc, Glycogen storage disease IXc |
| RS762089407 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS762089425 |
KCNJ11
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Permanent neonatal diabetes mellitus |
| RS762089971 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS762090058 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Intrauterine growth retardation, metaphyseal dysplasia |
| RS762090105 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Atrial septal defect 7 |
| RS762090852 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS762091081 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS762092284 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS762093483 |
PTRH2
|
Health Risk |
Likely pathogenic |
— |
| RS762093523 |
NDUFAF6
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Mitochondrial complex I deficiency |
| RS762094056 |
ADAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 6, Symmetrical dyschromatosis of extremities |
| RS762094907 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762096305 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS762096939 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS762097856 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Inborn genetic diseases |
| RS762098368 |
C6
|
Health Risk |
Pathogenic |
— |
| RS762099392 |
XPC
|
Health Risk |
Likely pathogenic |
Ovarian cancer, Ovarian cancer |
| RS762099920 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS762100304 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS762100538 |
GRID2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762101560 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 2, Usher syndrome type 1 |
| RS762103625 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiac arrhythmia |
| RS762103704 |
PKP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Arrhythmogenic right ventricular dysplasia 9, Cardiovascular phenotype |
| RS762104169 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS762104739 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS762105711 |
VWF
|
Health Risk |
Likely pathogenic |
Hereditary von Willebrand disease, Hereditary von Willebrand disease |
| RS762105733 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS76210637 |
LHCGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Gonadotropin-independent familial sexual precocity, Gonadotropin-independent familial sexual precocity |
| RS762106720 |
GNE
|
Health Risk |
Pathogenic/Likely pathogenic |
GNE myopathy, Sialuria |
| RS762106764 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS762108847 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS762108965 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS762110595 |
ALPK3
|
Health Risk |
Likely pathogenic |
Cardiomyopathy, familial hypertrophic 27 |
| RS762110822 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
MYO15A-related disorder, MYO15A-related disorder |
| RS762111359 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS762111552 |
SPTB
|
Health Risk |
Pathogenic |
— |
| RS762111572 |
IFT140
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 80 |
| RS762112077 |
ADAMTS13
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Inborn genetic diseases |