| RS752895450 |
RECQL4
|
Health Risk |
Likely pathogenic |
Baller-Gerold syndrome, RECQL4-related disorder |
| RS752895938 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752897010 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS752897450 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS752897486 |
ASNS
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752897516 |
ADCY5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752897955 |
TNFRSF13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunoglobulin A deficiency 2, Immunodeficiency |
| RS752898108 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752898811 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic acidemia |
| RS752899698 |
AEBP1
|
Health Risk |
Likely pathogenic |
— |
| RS752900825 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS752901414 |
ITGB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukocyte adhesion deficiency 1, Leukocyte adhesion deficiency 1 |
| RS752901695 |
NCF2
|
Health Risk |
Pathogenic |
Granulomatous disease, chronic |
| RS752902118 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS752902474 |
PNKP
|
Health Risk |
Pathogenic |
Microcephaly, seizures |
| RS752902486 |
ALDOB
|
Health Risk |
Pathogenic |
Hereditary fructosuria, Hereditary fructosuria |
| RS752903377 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Congenital myopathy |
| RS752903521 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS752904598 |
PEX3
|
Health Risk |
Pathogenic/Likely pathogenic |
PEX3-related disorder, Peroxisome biogenesis disorder 10A (Zellweger) |
| RS752905024 |
LPIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoglobinuria, acute recurrent |
| RS752905387 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS752905540 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS752905665 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS752906680 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS752907087 |
F11
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS75290777 |
COL17A1
|
Health Risk |
Pathogenic |
— |
| RS752907815 |
SPEG
|
Health Risk |
Pathogenic |
— |
| RS752908017 |
CSPP1
|
Health Risk |
Pathogenic |
Joubert syndrome 21, Joubert syndrome 21 |
| RS752908663 |
TICAM1
|
Health Risk |
Likely risk allele |
Susceptibility to severe COVID-19, Susceptibility to severe COVID-19 |
| RS752910161 |
CLRN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 61, Retinitis pigmentosa 61 |
| RS752910449 |
NPHP4
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS752910553 |
CASZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752911523 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS752911811 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS752913534 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS752914124 |
SGSH
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS752914246 |
AGA
|
Health Risk |
Conflicting classifications of pathogenicity |
Aspartylglucosaminuria, Aspartylglucosaminuria |
| RS752914914 |
LRPPRC
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type |
| RS752916256 |
CTU2
|
Health Risk |
Likely pathogenic |
— |
| RS752916287 |
ABCB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 3, Cholestasis |
| RS752916728 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Inborn genetic diseases |
| RS752918105 |
SCN1A
|
Health Risk |
Likely pathogenic |
— |
| RS752918613 |
OPHN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752918694 |
ANKRD11
|
Health Risk |
Pathogenic/Likely pathogenic |
KBG syndrome, Inborn genetic diseases |
| RS752919200 |
CTNS
|
Health Risk |
Pathogenic |
Nephropathic cystinosis, Ocular cystinosis |
| RS752919660 |
VMA22
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752919688 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS752919962 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS752919965 |
ABCB11
|
Health Risk |
Pathogenic |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS752920772 |
KMT2E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752920956 |
POLG
|
Health Risk |
Likely pathogenic |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS752921215 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS752921570 |
FKTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS752922461 |
ALG1
|
Health Risk |
Pathogenic |
Congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |
| RS752922900 |
LRRC56
|
Health Risk |
Conflicting classifications of pathogenicity |
LRRC56-related disorder, LRRC56-related disorder |
| RS752923595 |
BEST1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant vitreoretinochoroidopathy, Retinal dystrophy |
| RS752924139 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS752924362 |
DNAI2
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 9 |
| RS752924679 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS752925056 |
DNAH5
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS752926435 |
TBXAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752926571 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS752926638 |
GJA3
|
Health Risk |
Likely pathogenic |
Cataract 14 multiple types, Cataract 14 multiple types |
| RS752927520 |
GOT2
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 82 |
| RS752928106 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS752928207 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS752930400 |
EYS
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 25 |
| RS752931210 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2K |
| RS752931351 |
HPS4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752934195 |
RMRP
|
Health Risk |
Pathogenic |
Metaphyseal chondrodysplasia, McKusick type |
| RS752934825 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS752935094 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS752935686 |
SON
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752935814 |
LDLR
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS752937018 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS752937110 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS752937387 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS752937543 |
NBAS
|
Health Risk |
Likely pathogenic |
— |
| RS752939204 |
HGSNAT
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS752940775 |
CHD2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy 94, History of neurodevelopmental disorder |
| RS752940799 |
DYNC1I2
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with microcephaly and structural brain anomalies, Neurodevelopmental disorder with microcephaly |
| RS752940904 |
TRAPPC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 13 |
| RS752941297 |
SPINK5
|
Health Risk |
Pathogenic/Likely pathogenic |
Increased circulating IgE concentration, Erythroderma |
| RS752941420 |
POMT1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1 |
| RS752941845 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS752942007 |
SAMHD1
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 5, Aicardi-Goutieres syndrome 5 |
| RS752942122 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 14, Meckel syndrome |
| RS752942769 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Hypercholesterolemia |
| RS752946123 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Miyoshi muscular dystrophy 1 |
| RS752947034 |
TXNRD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Cardiovascular phenotype |
| RS752948071 |
MPI
|
Health Risk |
Conflicting classifications of pathogenicity |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS752948085 |
MYO6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 37, Autosomal dominant nonsyndromic hearing loss 22 |
| RS752948913 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS752948922 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS752949191 |
TK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome, myopathic form |
| RS752949328 |
LAMA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, LAMA5-related disorder |
| RS752950532 |
ANGPTL4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752951296 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS752951310 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS752951417 |
BRD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |