| RS752839330 |
LOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital aneurysm of ascending aorta, Acute aortic dissection |
| RS752839367 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS752839497 |
FHL1
|
Health Risk |
Pathogenic |
X-linked myopathy with postural muscle atrophy, X-linked myopathy with postural muscle atrophy |
| RS752839979 |
PUS7
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with abnormal behavior, microcephaly |
| RS752840373 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS752840782 |
CDSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752841251 |
NF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurofibromatosis, type 1 |
| RS752842243 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752842357 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Timothy syndrome |
| RS752843169 |
CUBN
|
Health Risk |
Likely pathogenic |
Imerslund-Grasbeck syndrome, Proteinuria |
| RS752843742 |
SPG7
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS752844520 |
ALPK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752844723 |
SCN3A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752845880 |
SCN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial infantile |
| RS752846043 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Medulloblastoma, Gorlin syndrome |
| RS752846235 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS752846577 |
PDE6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness autosomal dominant 2, Retinitis pigmentosa |
| RS752846614 |
POLE
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS752847512 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS752848213 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS752848452 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752848496 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS752848974 |
PYGM
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type V |
| RS752849270 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS752849283 |
COL17A1
|
Health Risk |
Likely pathogenic |
— |
| RS752850439 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752850582 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS752850609 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Wilson disease |
| RS752850659 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS752850661 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group J, Familial cancer of breast |
| RS752851284 |
PYGM
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type V |
| RS752851745 |
TENM1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752852871 |
TSFM
|
Health Risk |
Likely pathogenic |
Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3, Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3 |
| RS752854030 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 5 with or without anosmia, CHARGE syndrome |
| RS752856716 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS752857170 |
GRIN2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752857771 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS752857820 |
REV3L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752858024 |
MTRR
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylcobalamin deficiency type cblE, Neural tube defects |
| RS752858201 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752858869 |
PRF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Aplastic anemia |
| RS752858908 |
ALG6
|
Health Risk |
Pathogenic |
ALG6-congenital disorder of glycosylation 1C, ALG6-congenital disorder of glycosylation 1C |
| RS752859634 |
ZFYVE26
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 15, Spastic paraplegia |
| RS752860014 |
LAMA3
|
Health Risk |
Pathogenic |
— |
| RS752863502 |
VPS51
|
Health Risk |
Pathogenic |
Pontocerebellar hypoplasia, type 13 |
| RS752864098 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS752864343 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS752864722 |
NDUFAF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, Mitochondrial complex I deficiency |
| RS752865337 |
AXIN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Oligodontia-cancer predisposition syndrome, AXIN2-related disorder |
| RS752865665 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS752866323 |
GLUD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinism-hyperammonemia syndrome, Hyperinsulinism-hyperammonemia syndrome |
| RS752866557 |
MCCC2
|
Health Risk |
Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, 3-methylcrotonyl-CoA carboxylase 2 deficiency |
| RS752866643 |
MMAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblB type |
| RS752866783 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 2 |
| RS752868357 |
DYM
|
Health Risk |
Pathogenic |
Dyggve-Melchior-Clausen syndrome, Dyggve-Melchior-Clausen syndrome |
| RS752868449 |
SEC63
|
Health Risk |
Pathogenic/Likely pathogenic |
Polycystic liver disease 2, Polycystic liver disease 2 |
| RS752869470 |
SLC4A10
|
Health Risk |
Likely pathogenic |
— |
| RS752869602 |
TUBGCP6
|
Health Risk |
Pathogenic |
Microcephaly and chorioretinopathy 1, Microcephaly and chorioretinopathy 1 |
| RS752870879 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS752871814 |
MECR
|
Health Risk |
Pathogenic |
— |
| RS752871893 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS752872595 |
LAMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752873857 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS752874220 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, 6 conditions |
| RS752874408 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS752874782 |
FAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752874974 |
GNPTAB
|
Health Risk |
Pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS752875047 |
RIMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 7, Retinal dystrophy |
| RS752875933 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS752876192 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Breast and/or ovarian cancer |
| RS752877550 |
TUBGCP6
|
Health Risk |
Likely pathogenic |
— |
| RS752878085 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 5 |
| RS752878896 |
NEK1
|
Health Risk |
Likely pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS752879150 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS752879780 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS752880854 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Familial cancer of breast |
| RS752880958 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PIEZO1-related disorder |
| RS752881057 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752881223 |
AXIN2
|
Health Risk |
Pathogenic |
Non-syndromic oligodontia, Non-syndromic oligodontia |
| RS752881264 |
SCN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial infantile |
| RS752881588 |
SLC7A9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystinuria, Cystinuria |
| RS752883472 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS752883545 |
NR2E3
|
Health Risk |
Conflicting classifications of pathogenicity |
Enhanced S-cone syndrome, Enhanced S-cone syndrome |
| RS752884270 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS752886203 |
HNF1A
|
Health Risk |
Pathogenic |
Maturity-onset diabetes of the young type 3, Monogenic diabetes |
| RS752886421 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS752886472 |
CD36
|
Health Risk |
Pathogenic |
— |
| RS752886480 |
PTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS752886993 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS75288720 |
TSEN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontocerebellar hypoplasia type 2B, Pontoneocerebellar hypoplasia |
| RS752887801 |
BLTP1
|
Health Risk |
Pathogenic |
Alkuraya-Kucinskas syndrome, Alkuraya-Kucinskas syndrome |
| RS752887988 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS752889177 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS752889346 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS752890414 |
ADA2
|
Health Risk |
Likely pathogenic |
Deficiency of adenosine deaminase 2, Deficiency of adenosine deaminase 2 |
| RS752891084 |
MED13L
|
Health Risk |
Conflicting classifications of pathogenicity |
Dextro-looped transposition of the great arteries, Cardiac anomalies - developmental delay - facial dysmorphism syndrome |
| RS752891726 |
FBN1
|
Health Risk |
Likely pathogenic |
— |
| RS752892771 |
HPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 1, Hermansky-Pudlak syndrome 1 |
| RS752892850 |
PPP1R12A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752893483 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |