| RS1057518856 |
PKD1
|
Health Risk |
Likely pathogenic |
Hepatic cysts, Pancreatic cysts |
| RS1057518862 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Global developmental delay, Single transverse palmar crease |
| RS1057518863 |
COL7A1
|
Health Risk |
Likely pathogenic |
Finger syndactyly, Toe syndactyly |
| RS1057518864 |
TCF4
|
Health Risk |
Pathogenic |
7 conditions, Pitt-Hopkins syndrome |
| RS1057518865 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Myotonia, Handgrip myotonia |
| RS1057518866 |
DMD
|
Health Risk |
Pathogenic |
Myopathy, Duchenne muscular dystrophy |
| RS1057518867 |
ATP7B
|
Health Risk |
Likely pathogenic |
Kayser-Fleischer ring, Hand tremor |
| RS1057518868 |
FOXF1
|
Health Risk |
Likely pathogenic |
Atresia of urethra, Fetal megacystis |
| RS1057518871 |
COL5A1
|
Health Risk |
Likely pathogenic |
10 conditions, 10 conditions |
| RS1057518872 |
GJA1
|
Health Risk |
Pathogenic |
Cutaneous finger syndactyly, Intellectual disability |
| RS1057518873 |
SPAST
|
Health Risk |
Likely pathogenic |
Spastic paraparesis, Spastic paraparesis |
| RS1057518874 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraparesis, Gait disturbance |
| RS1057518878 |
MAF
|
Health Risk |
Likely pathogenic |
Developmental cataract, Developmental cataract |
| RS1057518879 |
PLOD1
|
Health Risk |
Pathogenic |
6 conditions, 8 conditions |
| RS1057518880 |
SPAST
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS1057518881 |
FBN1
|
Health Risk |
Likely pathogenic |
Lens subluxation, Tall stature |
| RS1057518883 |
FBN1
|
Health Risk |
Likely pathogenic |
7 conditions, 7 conditions |
| RS1057518884 |
NF1
|
Health Risk |
Likely pathogenic |
Neurofibromatosis, type 1 |
| RS1057518886 |
HMBS
|
Health Risk |
Pathogenic |
Fever, Vomiting |
| RS1057518887 |
SEPSECS
|
Health Risk |
Likely pathogenic |
7 conditions, Pontocerebellar hypoplasia type 2D |
| RS1057518888 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
9 conditions, Charcot-Marie-Tooth disease axonal type 2O |
| RS1057518890 |
PRRT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic kinesigenic dyskinesia, Inborn genetic diseases |
| RS1057518891 |
CHD7
|
Health Risk |
Pathogenic |
6 conditions, 6 conditions |
| RS1057518895 |
AIFM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Foot dorsiflexor weakness, Pes planus |
| RS1057518896 |
PHEX
|
Health Risk |
Pathogenic |
Hypophosphatemic rickets, Lower limb pain |
| RS1057518897 |
PKD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypertensive disorder, Multiple renal cysts |
| RS1057518898 |
DYNC2H1
|
Health Risk |
Pathogenic |
Fetal growth restriction, Narrow chest |
| RS1057518899 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, Hypertensive disorder |
| RS1057518900 |
SCN9A
|
Health Risk |
Pathogenic |
Pain insensitivity, Generalized epilepsy with febrile seizures plus |
| RS1057518901 |
APC
|
Health Risk |
Pathogenic |
Adenomatous colonic polyposis, Familial adenomatous polyposis 1 |
| RS1057518903 |
MEN1
|
Health Risk |
Pathogenic |
6 conditions, 6 conditions |
| RS1057518904 |
NF1
|
Health Risk |
Pathogenic |
Cafe au lait spots, multiple |
| RS1057518905 |
DPM3
|
Health Risk |
Likely pathogenic |
Myopathy, EMG: myopathic abnormalities |
| RS1057518906 |
PKD2
|
Health Risk |
Pathogenic |
Polycystic kidney disease, Polycystic kidney disease 2 |
| RS1057518907 |
GNAS
|
Health Risk |
Pathogenic |
8 conditions, Pseudohypoparathyroidism type 1B |
| RS1057518908 |
COL2A1
|
Health Risk |
Likely pathogenic |
6 conditions, 6 conditions |
| RS1057518909 |
FBN1
|
Health Risk |
Pathogenic |
Myopia, Tall stature |
| RS1057518910 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cockayne syndrome, Cerebrooculofacioskeletal syndrome 1 |
| RS1057518911 |
COL2A1
|
Health Risk |
Likely pathogenic |
Disproportionate short-limb short stature, Narrow chest |
| RS1057518912 |
FBN1
|
Health Risk |
Pathogenic |
Marfan syndrome, Marfan syndrome |
| RS1057518913 |
EHMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
6 conditions, Kleefstra syndrome 1 |
| RS1057518914 |
RPS6KA3
|
Health Risk |
Likely pathogenic |
14 conditions, 14 conditions |
| RS1057518915 |
PANK2
|
Health Risk |
Pathogenic |
Neurodegeneration, Hypoprebetalipoproteinemia |
| RS1057518916 |
SCN5A
|
Health Risk |
Likely pathogenic |
Syncope, Syncope |
| RS1057518917 |
FAM131B;CLCN1
|
Health Risk |
Pathogenic |
Myotonia, Congenital myotonia |
| RS1057518918 |
ARID1B
|
Health Risk |
Likely pathogenic |
6 conditions, Neoplasm |
| RS1057518919 |
PSEN1
|
Health Risk |
Pathogenic |
Mental deterioration, Dementia |
| RS1057518920 |
DSP
|
Health Risk |
Pathogenic |
Cardiac arrhythmia, Bicuspid aortic valve |
| RS1057518921 |
MED12
|
Health Risk |
Likely pathogenic |
7 conditions, 7 conditions |
| RS1057518922 |
RPE65
|
Health Risk |
Pathogenic |
Abnormality of vision, Abnormal electroretinogram |
| RS1057518923 |
PKD1
|
Health Risk |
Pathogenic |
Dilatation of the cerebral artery, Hepatic cysts |
| RS1057518925 |
COL6A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy, Hyperextensible hand joints |
| RS1057518926 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Anterior creases of earlobe |
| RS1057518927 |
OAT
|
Health Risk |
Likely pathogenic |
Optic atrophy, Abnormal choroid morphology |
| RS1057518928 |
SOX5
|
Health Risk |
Likely pathogenic |
Severe global developmental delay, Generalized hypotonia |
| RS1057518930 |
COL1A1
|
Health Risk |
Pathogenic |
Blue sclerae, Osteopenia |
| RS1057518932 |
EFTUD2
|
Health Risk |
Likely pathogenic |
Global developmental delay, Seizure |
| RS1057518933 |
CASR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypertrophic cardiomyopathy, Hypocalciuria |
| RS1057518934 |
HERC2
|
Health Risk |
Pathogenic |
8 conditions, 8 conditions |
| RS1057518935 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal lower limb muscle weakness, Inborn genetic diseases |
| RS1057518936 |
PNPLA6
|
Health Risk |
Pathogenic |
Hypogonadotropic hypogonadism 7 with or without anosmia, Dysarthria |
| RS1057518938 |
MYH11
|
Health Risk |
Likely pathogenic |
Myopia, Aortic root aneurysm |
| RS1057518939 |
VPS13B
|
Health Risk |
Pathogenic |
9 conditions, Cohen syndrome |
| RS1057518940 |
RYR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Delayed gross motor development, Congenital contracture |
| RS1057518942 |
NPC1
|
Health Risk |
Likely pathogenic |
Dystonic disorder, Dystonic disorder |
| RS1057518943 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lower limb muscle weakness, Difficulty walking |
| RS1057518944 |
NIPBL
|
Health Risk |
Likely pathogenic |
9 conditions, Cornelia de Lange syndrome 1 |
| RS1057518945 |
TSC1
|
Health Risk |
Likely pathogenic |
Cortical tubers, Adenoma sebaceum |
| RS1057518946 |
GJB1
|
Health Risk |
Likely pathogenic |
8 conditions, Charcot-Marie-Tooth Neuropathy X |
| RS1057518949 |
IMPDH1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Leber congenital amaurosis 11 |
| RS1057518950 |
TPO
|
Health Risk |
Likely pathogenic |
7 conditions, Deficiency of iodide peroxidase |
| RS1057518951 |
ARID1B
|
Health Risk |
Pathogenic |
Corpus callosum, agenesis of |
| RS1057518952 |
PKHD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, Ventricular hypertrophy |
| RS1057518953 |
SLC2A1
|
Health Risk |
Likely pathogenic |
Paroxysmal dystonia, GLUT1 deficiency syndrome 1 |
| RS1057518955 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal disorder, Visual impairment |
| RS1057518956 |
ZEB1
|
Health Risk |
Pathogenic |
Glaucoma, Visual loss |
| RS1057518957 |
CHRND
|
Health Risk |
Likely pathogenic |
Ptosis, Breathing dysregulation |
| RS1057518958 |
CHRND
|
Health Risk |
Likely pathogenic |
Ptosis, Breathing dysregulation |
| RS1057518959 |
PKD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Polycystic kidney disease, Hypertensive disorder |
| RS1057518960 |
GJA1
|
Health Risk |
Likely pathogenic |
7 conditions, Atrioventricular septal defect and common atrioventricular junction |
| RS1057518961 |
DYNC1H1
|
Health Risk |
Pathogenic/Likely pathogenic |
Delayed gross motor development, Delayed speech and language development |
| RS1057518962 |
DMD
|
Health Risk |
Pathogenic |
6 conditions, Dilated cardiomyopathy 3B |
| RS1057518963 |
OPHN1
|
Health Risk |
Likely pathogenic |
6 conditions, 6 conditions |
| RS1057518965 |
ATM
|
Health Risk |
Pathogenic/Likely pathogenic |
Immunodeficiency, Conjunctival telangiectasia |
| RS1057518966 |
MUSK
|
Health Risk |
Conflicting classifications of pathogenicity |
Delayed gross motor development, Bilateral ptosis |
| RS1057518967 |
COL1A2
|
Health Risk |
Pathogenic |
Multiple prenatal fractures, Skeletal dysplasia |
| RS1057518968 |
DTNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Noncompaction cardiomyopathy |
| RS1057518969 |
PKD2
|
Health Risk |
Pathogenic |
Polycystic kidney disease, Elevated systolic blood pressure |
| RS1057518970 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Respiratory insufficiency, Congenital muscular dystrophy |
| RS1057518971 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy, Charcot-Marie-Tooth disease type 2 |
| RS1057518972 |
TRPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Alopecia areata, Brachydactyly |
| RS1057518973 |
FBN1
|
Health Risk |
Pathogenic |
Mitral regurgitation, Ectopia lentis |
| RS1057518974 |
NF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Axillary freckling, Cafe-au-lait spot |
| RS1057518977 |
SMAD3
|
Health Risk |
Pathogenic |
Vascular dilatation, Aneurysm-osteoarthritis syndrome |
| RS1057518978 |
ADNP
|
Health Risk |
Pathogenic |
ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder, ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder |
| RS1057518980 |
KIF11
|
Health Risk |
Likely pathogenic |
Retinal dysplasia, Microcephaly |
| RS1057518981 |
RORA
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe intellectual deficiency, Intellectual developmental disorder with or without epilepsy or cerebellar ataxia |
| RS1057518984 |
ARID1B
|
Health Risk |
Pathogenic |
Coffin-Siris syndrome, Intellectual disability |
| RS1057518985 |
STXBP1
|
Health Risk |
Likely pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057518986 |
AUTS2
|
Health Risk |
Likely pathogenic |
Pierre Robin-like syndrome, Pierre Robin-like syndrome |