| RS1057518719 |
SLC35A2
|
Health Risk |
Pathogenic |
SLC35A2-congenital disorder of glycosylation, SLC35A2-congenital disorder of glycosylation |
| RS1057518721 |
BCAP31
|
Health Risk |
Pathogenic |
Severe motor and intellectual disabilities-sensorineural deafness-dystonia syndrome, Severe motor and intellectual disabilities-sensorineural deafness-dystonia syndrome |
| RS1057518722 |
SLC45A2
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 4, Oculocutaneous albinism type 4 |
| RS1057518723 |
AVPR2
|
Health Risk |
Likely pathogenic |
Diabetes insipidus, nephrogenic |
| RS1057518725 |
IRX5
|
Health Risk |
Pathogenic |
Craniofacial dysplasia - osteopenia syndrome, Craniofacial dysplasia - osteopenia syndrome |
| RS1057518727 |
HDAC8
|
Health Risk |
Likely pathogenic |
Cornelia de Lange syndrome 5, Cornelia de Lange syndrome 5 |
| RS1057518728 |
NEXMIF
|
Health Risk |
Pathogenic |
X-linked intellectual disability, Cantagrel type |
| RS1057518729 |
PHF8
|
Health Risk |
Pathogenic |
Syndromic X-linked intellectual disability Siderius type, Syndromic X-linked intellectual disability Siderius type |
| RS1057518730 |
NEXMIF
|
Health Risk |
Pathogenic |
X-linked intellectual disability, Cantagrel type |
| RS1057518731 |
SMARCD2
|
Health Risk |
Pathogenic |
Specific granule deficiency 2, Specific granule deficiency 1 |
| RS1057518733 |
SMARCD2
|
Health Risk |
Pathogenic |
Specific granule deficiency 1, Autosomal recessive severe congenital neutropenia |
| RS1057518735 |
SSR4
|
Health Risk |
Conflicting classifications of pathogenicity |
SSR4-congenital disorder of glycosylation, Thyroid cancer |
| RS1057518736 |
SSR4
|
Health Risk |
Pathogenic |
SSR4-congenital disorder of glycosylation, SSR4-congenital disorder of glycosylation |
| RS1057518738 |
FOXE3
|
Health Risk |
Pathogenic |
Cataract 34 multiple types, Cataract 34 multiple types |
| RS1057518741 |
MIPEP
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal left ventricular non-compaction-seizures-hypotonia-cataract-developmental delay syndrome, Cardiomyopathy |
| RS1057518742 |
TUFM
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 4, Combined oxidative phosphorylation defect type 4 |
| RS1057518743 |
TUFM
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation defect type 4, Combined oxidative phosphorylation defect type 4 |
| RS1057518744 |
IL17RA
|
Health Risk |
Pathogenic |
Immunodeficiency 51, Immunodeficiency 51 |
| RS1057518745 |
IL17RA
|
Health Risk |
Pathogenic |
Immunodeficiency 51, Immunodeficiency 51 |
| RS1057518746 |
IL17RA
|
Health Risk |
Pathogenic |
Immunodeficiency 51, Immunodeficiency 51 |
| RS1057518747 |
IL17RA
|
Health Risk |
Pathogenic |
Immunodeficiency 51, Immunodeficiency 51 |
| RS1057518748 |
SLC25A46
|
Health Risk |
Pathogenic |
Neuropathy, hereditary motor and sensory |
| RS1057518749 |
SLC25A46
|
Health Risk |
Likely pathogenic |
Pontocerebellar hypoplasia, type 1E |
| RS1057518750 |
SLC25A46
|
Health Risk |
Pathogenic |
Pontocerebellar hypoplasia, type 1E |
| RS1057518751 |
IL17RC
|
Health Risk |
Pathogenic |
Candidiasis, familial |
| RS1057518752 |
ACAD9
|
Health Risk |
Pathogenic |
Acyl-CoA dehydrogenase 9 deficiency, Acyl-CoA dehydrogenase 9 deficiency |
| RS1057518753 |
CEP78
|
Health Risk |
Pathogenic |
Cone-rod dystrophy and hearing loss 1, Cone-rod dystrophy and hearing loss 1 |
| RS1057518754 |
PYROXD1
|
Health Risk |
Pathogenic |
Myofibrillar myopathy 8, Myofibrillar myopathy 8 |
| RS1057518755 |
PYROXD1
|
Health Risk |
Pathogenic |
Myofibrillar myopathy 8, Myofibrillar myopathy 8 |
| RS1057518759 |
CDKL5
|
Health Risk |
Likely pathogenic |
Developmental delay, Epileptic encephalopathy |
| RS1057518760 |
KIF1A
|
Health Risk |
Pathogenic |
Spastic paraplegia, Hyperreflexia |
| RS1057518761 |
PAX2
|
Health Risk |
Likely pathogenic |
Renal cyst, Renal cyst |
| RS1057518763 |
TYR
|
Health Risk |
Pathogenic |
Ocular albinism, Oculocutaneous albinism type 1A |
| RS1057518764 |
DLX3
|
Health Risk |
Likely pathogenic |
Amelogenesis imperfecta, Peripheral pulmonary artery stenosis |
| RS1057518765 |
MITF
|
Health Risk |
Likely pathogenic |
Waardenburg syndrome, Waardenburg syndrome |
| RS1057518766 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive neurodegenerative disease, Hereditary glaucoma |
| RS1057518767 |
ABCA4
|
Health Risk |
Pathogenic |
Central scotoma, Macular degeneration |
| RS1057518770 |
UBE3A
|
Health Risk |
Pathogenic |
6 conditions, 6 conditions |
| RS1057518772 |
KCNQ2
|
Health Risk |
Pathogenic |
Intellectual disability, Developmental and epileptic encephalopathy |
| RS1057518773 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, RYR1-related disorder |
| RS1057518775 |
KCNJ11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemia, Atopic eczema |
| RS1057518776 |
DYNC1H1
|
Health Risk |
Likely pathogenic |
Global developmental delay, Hypotonia |
| RS1057518777 |
UBE3A
|
Health Risk |
Likely pathogenic |
Intellectual disability, Developmental delay |
| RS1057518779 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraparesis, Cerebellar ataxia |
| RS1057518780 |
GJB1
|
Health Risk |
Likely pathogenic |
Pes cavus, Hammertoe |
| RS1057518781 |
MCOLN1
|
Health Risk |
Pathogenic |
7 conditions, Mucolipidosis type IV |
| RS1057518782 |
MCOLN1
|
Health Risk |
Likely pathogenic |
7 conditions, 7 conditions |
| RS1057518783 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS1057518786 |
SYNGAP1
|
Health Risk |
Likely pathogenic |
Preauricular skin tag, Delayed speech and language development |
| RS1057518787 |
GPR143
|
Health Risk |
Pathogenic/Likely pathogenic |
Nystagmus, Ocular albinism |
| RS1057518788 |
DSG1
|
Health Risk |
Likely pathogenic |
Hereditary palmoplantar keratoderma, Bicuspid aortic valve |
| RS1057518789 |
CREBBP
|
Health Risk |
Pathogenic |
Scoliosis, Global developmental delay |
| RS1057518791 |
TRPS1
|
Health Risk |
Likely pathogenic |
7 conditions, 7 conditions |
| RS1057518792 |
NF1
|
Health Risk |
Pathogenic |
Cafe au lait spots, multiple |
| RS1057518793 |
NDP
|
Health Risk |
Likely pathogenic |
Atrophia bulborum hereditaria, Retinal dystrophy |
| RS1057518794 |
ARX
|
Health Risk |
Likely pathogenic |
Generalized hypotonia, Generalized hypotonia |
| RS1057518795 |
WWOX
|
Health Risk |
Pathogenic/Likely pathogenic |
Epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS1057518796 |
SYNGAP1
|
Health Risk |
Likely pathogenic |
Cerebellar ataxia, Global developmental delay |
| RS1057518797 |
PKD2
|
Health Risk |
Pathogenic |
Polycystic kidney disease, Hypertensive disorder |
| RS1057518798 |
PPOX
|
Health Risk |
Likely pathogenic |
Abnormal blistering of the skin, Porphyrinuria |
| RS1057518799 |
POGZ
|
Health Risk |
Likely pathogenic |
7 conditions, 7 conditions |
| RS1057518800 |
GRIN2B
|
Health Risk |
Likely pathogenic |
Intellectual disability, Developmental delay |
| RS1057518801 |
SCN3A
|
Health Risk |
Pathogenic |
Polymicrogyria, Developmental delay |
| RS1057518802 |
COL18A1
|
Health Risk |
Pathogenic |
Cataract, High myopia |
| RS1057518805 |
SYT2
|
Health Risk |
Likely pathogenic |
Muscle weakness, Respiratory distress |
| RS1057518806 |
HMBS
|
Health Risk |
Likely pathogenic |
Elevated urinary delta-aminolevulinic acid, Acute episodes of neuropathic symptoms |
| RS1057518807 |
NF1
|
Health Risk |
Pathogenic |
Subcutaneous neurofibroma, Cafe au lait spots |
| RS1057518809 |
FBN1
|
Health Risk |
Likely pathogenic |
Aortic dissection, Polycystic liver disease 1 |
| RS1057518810 |
SLC26A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Hearing impairment |
| RS1057518811 |
DEAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
9 conditions, Intellectual disability-epilepsy-extrapyramidal syndrome |
| RS1057518812 |
FBN1
|
Health Risk |
Pathogenic |
7 conditions, 7 conditions |
| RS1057518813 |
ERCC5
|
Health Risk |
Likely pathogenic |
8 conditions, 8 conditions |
| RS1057518816 |
FOLR1
|
Health Risk |
Likely pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057518817 |
NPR2
|
Health Risk |
Likely pathogenic |
Growth delay, Limb undergrowth |
| RS1057518821 |
SLC2A1
|
Health Risk |
Pathogenic |
Cerebellar ataxia, Global developmental delay |
| RS1057518822 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Blindness, Nystagmus |
| RS1057518826 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital sensorineural hearing impairment, Usher syndrome type 2A |
| RS1057518827 |
NLRP3
|
Health Risk |
Likely pathogenic |
Pericardial effusion, Pleural effusion |
| RS1057518828 |
GFAP
|
Health Risk |
Likely pathogenic |
Scoliosis, Scoliosis |
| RS1057518829 |
CACNA1F
|
Health Risk |
Pathogenic |
Amblyopia, Myopia |
| RS1057518830 |
STK11
|
Health Risk |
Likely pathogenic |
Periorbital hyperpigmentation, Intestinal polyposis |
| RS1057518832 |
ACO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodegeneration, Progressive microcephaly |
| RS1057518834 |
DMD
|
Health Risk |
Likely pathogenic |
9 conditions, Dilated cardiomyopathy 3B |
| RS1057518836 |
NDP
|
Health Risk |
Likely pathogenic |
Persistent hyperplastic primary vitreous, High myopia |
| RS1057518837 |
ITGB3
|
Health Risk |
Pathogenic |
Abnormal bleeding, Prolonged bleeding time |
| RS1057518838 |
ITGB3
|
Health Risk |
Likely pathogenic |
Abnormal bleeding, Prolonged bleeding time |
| RS1057518839 |
MPZ
|
Health Risk |
Likely pathogenic |
EMG: neuropathic changes, Limb muscle weakness |
| RS1057518840 |
OTOF
|
Health Risk |
Likely pathogenic |
Hearing impairment, Hearing impairment |
| RS1057518841 |
TYRP1
|
Health Risk |
Likely pathogenic |
Ocular albinism, Ocular albinism |
| RS1057518842 |
NF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cafe-au-lait spot, Inguinal freckling |
| RS1057518843 |
GALC
|
Health Risk |
Likely pathogenic |
19 conditions, Galactosylceramide beta-galactosidase deficiency |
| RS1057518844 |
CREBBP
|
Health Risk |
Pathogenic/Likely pathogenic |
Glaucoma, Thumb deformity |
| RS1057518845 |
SOX5
|
Health Risk |
Likely pathogenic |
Aplasia/Hypoplasia of the nails, Generalized hypotonia |
| RS1057518846 |
AAGAB
|
Health Risk |
Likely pathogenic |
Palmoplantar keratoderma, Palmoplantar keratoderma |
| RS1057518848 |
TCF4
|
Health Risk |
Pathogenic |
Global developmental delay, Cerebral hypoplasia |
| RS1057518849 |
EHMT1
|
Health Risk |
Likely pathogenic |
Difficulty walking, Abnormal facial shape |
| RS1057518850 |
FMR1
|
Health Risk |
Likely pathogenic |
Intellectual disability, Autistic behavior |
| RS1057518851 |
TTN
|
Health Risk |
Pathogenic |
Myopathy, Myopathy |
| RS1057518853 |
RPS6KA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Global developmental delay, Coffin-Lowry syndrome |
| RS1057518855 |
ANO5
|
Health Risk |
Likely pathogenic |
Myopathy, Gnathodiaphyseal dysplasia |