| RS762292061 |
F2
|
Health Risk |
Pathogenic |
Congenital prothrombin deficiency, Congenital prothrombin deficiency |
| RS762292335 |
RSPH9
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS762292619 |
CLCN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Familial hyperaldosteronism type II |
| RS762292772 |
SHANK3
|
Health Risk |
Pathogenic/Likely pathogenic |
Phelan-McDermid syndrome, Inborn genetic diseases |
| RS762294904 |
CACNA1S
|
Health Risk |
Pathogenic |
Hypokalemic periodic paralysis, type 1 |
| RS762297266 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS762297795 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS762297923 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762299598 |
COL6A1
|
Health Risk |
Likely pathogenic |
— |
| RS762299976 |
VCAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopia 25, autosomal dominant |
| RS762301873 |
ZNF469
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Ehlers-Danlos syndrome |
| RS762302341 |
FARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 14, Hereditary spastic paraplegia 77 |
| RS762302707 |
SEC23B
|
Health Risk |
Pathogenic |
Congenital dyserythropoietic anemia, type II |
| RS762302738 |
KAT6A
|
Health Risk |
Conflicting classifications of pathogenicity |
History of neurodevelopmental disorder, History of neurodevelopmental disorder |
| RS762303621 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperparathyroidism, Multiple endocrine neoplasia |
| RS762304556 |
TH
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive DOPA responsive dystonia, Dystonia 5 |
| RS762304847 |
GFI1B
|
Health Risk |
Pathogenic |
Platelet-type bleeding disorder 17, Platelet-type bleeding disorder 17 |
| RS762305947 |
LAMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMP2-related disorder, LAMP2-related disorder |
| RS762306750 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS762307622 |
MUTYH
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS762308378 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS762309206 |
ERCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
Xeroderma pigmentosum, group D |
| RS762310676 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS762311530 |
WNT10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Odonto-onycho-dermal dysplasia, Schöpf-Schulz-Passarge syndrome |
| RS762312642 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stiff skin syndrome, Ectopia lentis 1 |
| RS762313482 |
THBD
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762313648 |
GRHPR
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrolithiasis/nephrocalcinosis, Primary hyperoxaluria |
| RS762313659 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, DNAH5-related disorder |
| RS762314080 |
NBEA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762314534 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS762314651 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 42, Spinocerebellar ataxia type 42 |
| RS762315953 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS762316414 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762317674 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, SCN1A-related disorder |
| RS762320051 |
RPGRIP1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS762320484 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS762321137 |
SERPINA1
|
Health Risk |
Likely pathogenic |
Alpha-1-antitrypsin deficiency, Alpha-1-antitrypsin deficiency |
| RS762321473 |
TBX6
|
Health Risk |
Likely pathogenic |
Spondylocostal dysostosis 5, Spondylocostal dysostosis 5 |
| RS762322213 |
VLDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762322858 |
NPHP1
|
Health Risk |
Likely pathogenic |
Joubert syndrome with renal defect, Joubert syndrome with renal defect |
| RS762323327 |
MRE11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia-like disorder |
| RS762324196 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 6, WFS1-Related Spectrum Disorders |
| RS762324548 |
PEX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Heimler syndrome 1, Peroxisome biogenesis disorder 1A (Zellweger) |
| RS762326108 |
RLBP1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS762327114 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS762327241 |
C6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762327635 |
HPS5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 5, Hermansky-Pudlak syndrome 5 |
| RS762327729 |
MPV17
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 6 (hepatocerebral type), Mitochondrial DNA depletion syndrome 6 (hepatocerebral type) |
| RS762329183 |
VPS13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762330685 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS762331610 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS762332809 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Complement component 3 deficiency, Atypical hemolytic-uremic syndrome with C3 anomaly |
| RS762334108 |
CYP24A1
|
Health Risk |
Pathogenic |
Hypercalcemia, infantile |
| RS762334378 |
TBR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual developmental disorder with autism and speech delay |
| RS762334457 |
DAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A9 |
| RS762334514 |
CPLANE1
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Orofaciodigital syndrome type 6 |
| RS762334954 |
OBSL1
|
Health Risk |
Pathogenic |
3M syndrome 2, 3M syndrome 2 |
| RS762336160 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS762336270 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Adams-Oliver syndrome 5 |
| RS762336297 |
NPHS2
|
Health Risk |
Pathogenic |
Idiopathic nephrotic syndrome, Nephrotic syndrome |
| RS762336338 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS762339011 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Ehlers-Danlos syndrome |
| RS762341335 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS762341786 |
BCHE
|
Health Risk |
Likely pathogenic |
Deficiency of butyrylcholinesterase, Deficiency of butyrylcholinesterase |
| RS762342110 |
LAMA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Merosin deficient congenital muscular dystrophy, Muscular dystrophy |
| RS762342197 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS762342379 |
ARSK
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, type 10 |
| RS762343454 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS762344462 |
CLCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Batten-Turner congenital myopathy, Congenital myotonia |
| RS762345055 |
DOK7
|
Health Risk |
Pathogenic/Likely pathogenic |
Abnormality of the musculature, Congenital myasthenic syndrome 10 |
| RS762346634 |
ABCC2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Dubin-Johnson syndrome |
| RS762347776 |
CYP11B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of steroid 11-beta-monooxygenase, Glucocorticoid-remediable aldosteronism |
| RS762348061 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS762349361 |
ATAD3A
|
Health Risk |
Likely pathogenic |
— |
| RS762351406 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762352013 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spastic paraplegia |
| RS762352115 |
MARVELD2
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 49, Rare genetic deafness |
| RS762352116 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS762352363 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Donnai-Barrow syndrome |
| RS762354041 |
BLM
|
Health Risk |
Pathogenic |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS762354802 |
TRIM24
|
Health Risk |
Likely pathogenic |
Ovarian cancer, Ovarian cancer |
| RS762354873 |
PCCB
|
Health Risk |
Likely pathogenic |
Propionic acidemia, Propionic acidemia |
| RS762355724 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762356801 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS762356843 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 2, KMT2C-related disorder |
| RS762357071 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762358335 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS762358589 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Usher syndrome type 2A |
| RS762359799 |
NYX
|
Health Risk |
Pathogenic |
— |
| RS762361277 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Elliptocytosis 2, Hereditary spherocytosis type 3 |
| RS762361602 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762362960 |
CDK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial melanoma, Melanoma |
| RS762363112 |
WASHC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 8, Incidental Discovery |
| RS762363452 |
ATP8B1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762363654 |
POC1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762365764 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS762366252 |
CPT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine palmitoyl transferase II deficiency, severe infantile form |
| RS762366874 |
CCT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis, Leber congenital amaurosis |
| RS762367899 |
CEACAM16
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |
| RS762368225 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |