| RS762368526 |
CP
|
Health Risk |
Pathogenic |
Deficiency of ferroxidase, CP-related disorder |
| RS762368691 |
CHRNE
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome, Congenital myasthenic syndrome 4A |
| RS762369288 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS762369653 |
NDUFS1
|
Health Risk |
Pathogenic |
— |
| RS762370059 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS762370783 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS762371581 |
NPHP4
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephronophthisis 4, Senior-Loken syndrome 4 |
| RS762371629 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS762372863 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiomyopathy |
| RS762374961 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS762375074 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, MAN2B1-related disorder |
| RS762376423 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 6, Dilated cardiomyopathy 1HH |
| RS762376719 |
HYDIN
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 5, Primary ciliary dyskinesia 5 |
| RS762377424 |
MKS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS762379051 |
WRN
|
Health Risk |
Pathogenic/Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS762379765 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Neuromuscular disease caused by qualitative or quantitative defects of dystrophin |
| RS762380973 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Retinoblastoma |
| RS762381137 |
CASQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS762381405 |
SPG11
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia 11 |
| RS762382027 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS762382111 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS762382303 |
ANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 1, Spherocytosis |
| RS762382517 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS762382791 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762382800 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 12 |
| RS762383370 |
TF
|
Health Risk |
Conflicting classifications of pathogenicity |
Atransferrinemia, Atransferrinemia |
| RS762383457 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypocalciuric hypercalcemia, Autosomal dominant hypocalcemia 1 |
| RS762383656 |
SERPINF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 6, Osteogenesis imperfecta type 6 |
| RS762384558 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS762384825 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Rapadilino syndrome |
| RS762385137 |
MSH2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Lynch syndrome 1 |
| RS762385362 |
COL6A2
|
Health Risk |
Pathogenic |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS762387250 |
PMS2
|
Health Risk |
Pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Hereditary nonpolyposis colorectal neoplasms |
| RS762387914 |
ASS1
|
Health Risk |
Pathogenic |
Citrullinemia type I, Citrullinemia |
| RS762388072 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 39 |
| RS762388639 |
VAC14
|
Health Risk |
Pathogenic |
Striatonigral degeneration, childhood-onset |
| RS762388937 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinase-positive oculocutaneous albinism, Tyrosinase-positive oculocutaneous albinism |
| RS762389271 |
NALCN
|
Health Risk |
Likely pathogenic |
Arthrogryposis multiplex congenita, Fetal akinesia deformation sequence 1 |
| RS762389933 |
GPR179
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness 1E, GPR179-related disorder |
| RS762390227 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant optic atrophy classic form, Autosomal dominant optic atrophy classic form |
| RS762390488 |
VPS13A
|
Health Risk |
Pathogenic |
— |
| RS762390984 |
FANCI
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group I, Fanconi anemia |
| RS762392183 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Finnish congenital nephrotic syndrome, Congenital nephrotic syndrome |
| RS762393900 |
ARSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Chondrodysplasia punctata, brachytelephalangic |
| RS762394148 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS762394421 |
CACNB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Episodic ataxia type 5 |
| RS762394978 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS762395098 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Inborn genetic diseases |
| RS762395127 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS762396014 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS762396810 |
RBBP8
|
Health Risk |
Likely pathogenic |
Seckel syndrome 2, Seckel syndrome 2 |
| RS762397075 |
ALG12
|
Health Risk |
Pathogenic/Likely pathogenic |
ALG12-congenital disorder of glycosylation, ALG12-congenital disorder of glycosylation |
| RS762397298 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial melanoma |
| RS762398286 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS762398457 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KBG syndrome |
| RS762398743 |
NDUFAF3
|
Health Risk |
Pathogenic |
Mitochondrial complex I deficiency, nuclear type 18 |
| RS762398889 |
DYSF
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Miyoshi muscular dystrophy 1 |
| RS762398929 |
BEST1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS762399773 |
COL4A5
|
Health Risk |
Pathogenic |
— |
| RS762399936 |
IDUA
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis type 1, Hurler syndrome |
| RS762399977 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, CHD7-related disorder |
| RS762400331 |
NEU1
|
Health Risk |
Pathogenic/Likely pathogenic |
Sialidosis, Sialidosis |
| RS762400500 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
6 conditions, Marfan syndrome |
| RS762401591 |
WASHC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 8, Ritscher-Schinzel syndrome |
| RS762401851 |
RYR1
|
Health Risk |
Likely pathogenic |
Malignant hyperthermia, susceptibility to |
| RS762402822 |
TRDN
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS762402992 |
HGSNAT
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS762403277 |
ZBTB18
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762403314 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Alstrom syndrome |
| RS762403631 |
NUP93
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 12 |
| RS762404021 |
EVC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Curry-Hall syndrome |
| RS762404960 |
POMK
|
Health Risk |
Conflicting classifications of pathogenicity |
Limb-girdle muscular dystrophy due to POMK deficiency, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS762405291 |
CERKL
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa 26 |
| RS762406098 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS762406780 |
FMC1;FMC1-LUC7L2;LUC7L2
|
Health Risk |
Likely pathogenic |
Usher syndrome, Usher syndrome |
| RS762406949 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
Otitis media, susceptibility to |
| RS762406982 |
FANCD2
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group D2, Fanconi anemia complementation group D2 |
| RS762407683 |
KIAA1549
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762407803 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Inborn genetic diseases |
| RS762407838 |
RAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Histiocytic medullary reticulosis, Atypical severe combined immunodeficiency due to complete RAG1/2 deficiency |
| RS762408471 |
SBF2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4B2, Charcot-Marie-Tooth disease type 4B2 |
| RS762408726 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS762408736 |
PMM2
|
Health Risk |
Likely pathogenic |
PMM2-congenital disorder of glycosylation, PMM2-congenital disorder of glycosylation |
| RS762409067 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762409753 |
EFEMP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa, autosomal recessive |
| RS762411583 |
IDUA
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-I-S |
| RS762411631 |
TTN
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS762412096 |
FANCI
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS762412447 |
SGCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2E, Autosomal recessive limb-girdle muscular dystrophy type 2E |
| RS762412759 |
CYP11A1
|
Health Risk |
Pathogenic |
Congenital adrenal insufficiency with 46, XY sex reversal OR 46 |
| RS762413841 |
LRPPRC
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762416121 |
MCM8
|
Health Risk |
Pathogenic |
Premature ovarian failure 10, Premature ovarian failure 10 |
| RS762417023 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS762419044 |
BCKDHB
|
Health Risk |
Likely pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 1B |
| RS762419846 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS762420580 |
KMT2E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762421117 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS762422694 |
UBR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762422999 |
ACOX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Acyl-CoA oxidase deficiency, Acyl-CoA oxidase deficiency |
| RS762423563 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |